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Head and Neck Cancer Research Lab

Projects

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Lab members working together to conduct research.
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Collaboration

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Lab members working together to conduct research

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Dr. Fredrick and team
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Lab Leadership

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Dr. Mitchell Frederick and lab members. 

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The following are our key focus areas of research:

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Human Papillomavirus (HPV)-Associated Head and Neck Cancer

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Cancers of the throat (known as the “oropharynx”) caused by HPV have sharply increased over the past decade, and HPV-related oropharyngeal cancers are projected to exceed cervical cancers in the United States by the year 2020. We study the unique immunobiology of HPV-related cancer in mouse models and human clinical trials in order to develop new diagnostic and therapeutic approaches for this rapidly increasing cancer.

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Mechanisms of Cancer-Mediated Immune Suppression

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The focus of this research is understanding interactions of radiotherapy and chemotherapy with the immune system. Radiation has both immunosuppressive and immune stimulating effects. We have developed strategies for modeling the tumor immune microenvironment in order to unleash the beneficial immune stimulating effects of radiation-based therapies.

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Head and Neck Cancer Research Lab

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Contact: Research Administration Associate, Mariana Villanueva, M.S.
Phone: (713) 798-4529
Email: mariana.villanueva@bcm.edu

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Clinical Trials

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Clinical trials are conducted to test whether a new drug, prevention strategy, or screening test is safe and effective in people.