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Neurology

Houston, Texas

The Cullen Building at Baylor College of Medicine.
Department of Neurology
not shown on screen

Second Neurocritical Care Research Conference

Neurocritical Care Research Conference

May 18 – 20, 2012

Houston Marriott
at the Texas Medical Center
6580 Fannin St.
Houston, Texas 77030

Hotel information

Dear Conference Participants:

We are excited to welcome you to the Second Neurocritical Care Research Conference and to Houston. We hope you will find the next 2½ days as stimulating as it has been for us the planning of this great event. This symposium has been funded by NINDS (1R13NS077610-01, P.I. Jose I. Suarez), St Luke’s Episcopal Hospital in Houston, and the Integra Foundation, and endorsed by the Baylor College of Medicine and the Neurocritical Care Society.

The overall goal of this interdisciplinary scientific gathering is to bring together a diverse group of academic scientists and physicians from diverse fields with a common interest in understanding and advancing research in multimodality monitoring in neurocritical care diseases. The symposium is unique in that it will provide a forum for presenting and discussing the latest advances in clinical trial design, research tools, and research priorities in the field of neuromonitoring. The need for the design of adequate clinical studies to test these monitoring techniques will also be addressed in the context of the recently created Neurocritical Care Research Network (NCRN) to facilitate collaboration and patient enrollment. In addition, this conference will provide a unique opportunity for trainees, junior faculty, and other scientists to interact with investigators in the field of neurocritical care.

At the conclusion of this program, participants will be able to:

  1. Understand the importance and opportunities for research in multimodality monitoring in neurocritical care diseases
  2. Discuss recent scientific advances related to conventional and alternative clinical trial design and research tools that will have an impact on multimodality monitoring research;
  3. Determine the future directions of research of multimodality neuromonitoring;
  4. Initiate collaborations via NCRN and other networks for multimodality neuromonitoring research.

We expect and encourage you to participate actively in the discussions following each session since your thoughts will be extremely important to complement the presentations. Your presence for the entire conference will be required. Session moderators and conference organizers will collate the information discussed throughout the meeting and prepare summary statements for publication in Neurocritical Care. In addition, we will be videotaping the entire event and the formatted videos will be posted at the website of the Neurocritical Care Society for public access.

All activities related to this conference will take place at the Marriott Houston at the Texas Medical Center (6580 Fannin St., Houston, TX 77030). We appreciate and thank you for your participation.

Sincerely,

Jose I. Suarez, M.D.
Peter D. LeRoux, M.D.

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Speakers and Planning Committee

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Organizing Committee

Dr. Jose I. Suarez

Jose I. Suarez, M.D.

Professor of Neurology
Baylor College of Medicine
Houston, TX

Dr. Peter D. LeRoux

Peter D. LeRoux, M.D.

Associate Professor of Neurosurgery
University of Pennsylvania
Philadelphia, PA

Dr. W. Andrew Kofke

W. Andrew Kofke, M.D.

Professor of Neurosurgery, Anesthesiology and Critical Care
University of Pennsylvania
Philadelphia, PA

Photo Not Available

Eusebia Calvillo, R.N.

Research Coordinator
Baylor College of Medicine
Houston, TX

Photo Not Available

Theresa Kukic

Conference Management Solutions
Bethel Park, PA

Speakers

Randall Chestnut, M.D.

Professor of Neurological Surgery, and Orthopaedics & Sports Medicine
University of Washington
Seattle, WA

Giuseppe Citerio, M.D.

Director of Neuroanesthesia and Neuro Intensive Care Unit
San Gerardo Hospital
Monza, Italy

Robert S. B. Clark, M.D.

Professor of Critical Care Medicine and Pediatrics
University of Pittsburgh
Pittsburgh, PA

Michael Diringer, M.D.

Professor of Neurology and Neurosurgery
Washington University
St Louis, MO

Romergryko Geocadin, M.D.

Associate Professor of Anesthesiology/Critical
Care Medicine
Johns Hopkins University
Baltimore, MD

Puneet Gupta, M.D., M.S.E.

Assistant Professor of Neurology and Neurotherapeutics
University of Texas Southwestern
Dallas, TX

Claude Hemphill III, M.D.

Professor of Clinical Neurology and Neurological Surgery
University of California, San Francisco
San Francisco, CA

Peter J. Kirkpatrick

University of Cambridge
Cambridge, United Kingdom

W. Andrew Kofke, M.D.

Professor of Neurosurgery, Anesthesiology
and Critical Care
University of Pennsylvania
Philadelphia, PA

Geoffrey T. Manley, M.D., Ph.D.

Professor of Neurosurgery
University of California, San Francisco
San Francisco, CA

Renee H. Martin, Ph.D.

Assistant Professor of Medicine
Medical University of South Carolina
Charleston, SC

Andrew I. R. Mass, M.D., Ph.D.

University Hospital of Antwerp
Antwerp, Belgium

Richard Moberg

President
Moberg Research
Ambler, PA

Kristine O'Phelan, M.D.

Associate Professor of Clinical Neurology
University of Miami
Miami, FL

DaiWai Olson, Ph.D., R.N.

Assistant Professor of Medicine
Duke University
Durham, NC

Yuko Y. Palesch, Ph.D.

Professor of Biostatistics, Bioinformatics and Epidemiology
Medical University of South Carolina
Charleston, SC

Soojin Park, M.D.

Assistant Professor of Neurology
University of Pennsylvania
Philadelphia, PA

Claudia S. Robertson, M.D.

Professor of Neurosurgery
Baylor College of Medicine
Houston, TX

Stelios Smirnakis, M.D., Ph.D.

Assistant Professor of Neurology and Neuroscience
Baylor College of Medicine
Houston, TX

Michael J. Souter, M.D.

Professor of Anesthesiology and Pain Medicine
University of Washington
Seattle, WA

Jose I. Suarez, M.D.

Professor of Neurology
Baylor College of Medicine
Houston, TX

Gene Sung, M.D., M.P.H.

Associate Professor of Neurology
University of Southern California
Los Angeles, CA

Christine Wijman, M.D., Ph.D.

Associate Professor of Neurology and Neurological Sciences
Stanford University
Palo Alto, CA

Howard Yonas, M.D.

Professor of Neurosurgery
University of New Mexico
Albuquerque, NM

David Zygun, M.D.

Assistant Professor of Clinical Neurosciences
University of Calgary
Alberta, Canada

Conference Schedule

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Friday, May 18, 2012

6:00 p.m.

6:30

9:00

Registration

Welcoming Dinner and Reception
Opening Remarks

Jose I. Suarez, M.D.
NINDS Representative
Baylor College of Medicine and St. Luke's Episcopal Hospital Representative

Session Ends

Saturday, May 19, 2012

7:30 a.m.

8:00

8:30

9:00

9:30

9:45

10:15

10:45

11:15

11:45

12:00 Noon

1:00

1:30

2:00

2:30

3:00

3:15

3:30

4:00

4:30

5:00

5:30

5:45

6:00

7:00

7:15

9:00

Registration

Breakfast

History and Goals of the Meeting

Jose I. Suarez, M.D.

Multifaceted Therapeutic Bundles in Neurocritical Care: A New Approach

W. Andrew Kofke, M.D.

Coffee Break

Global Monitoring in the Neurocritical Care Unit ^

Moderator: Dai Wai Olson, Ph.D., R.N.

Intracranial Pressure Monitoring

Kristine O'Phelan, M.D.

Electrophysiology: EEG and Evoked Potentials

Puneet Gupta, M.D., M.S.E.

MRI Techniques

Stelios Smimakis, M.D., Ph.D.

CT Scanning

Howard Yonas, M.D.

Questions and Comments

Lunch Break

Regional Brain Monitoring in the Neurocrtitical Care Unit ^

Moderator: Christine Wijman, M.D., Ph.D.

Microdialysis

Kristine O'Phelan, M.D.

Brain Tissue Oxygenation

Peter D. LeRoux, M.D.

Regional CBF

Peter J. Kirkpatrick

CBF Monitoring

Michael Diringer, M.D.

Questions and Comments

Coffee Break

Data Collection and Interpretation ^

Moderator: Peter D. Leroux, M.D.

Standardization of Data Acquisition

Giuseppe Citerio, M.D.

Data Display and Visualization

Soojin Park, M.D.

Data Analysis and Interpretation

Geoffrey T. Manley, M.D., Ph.D.

Integrating Multiple Monitors in a User-Friendly Format

Richard Moberg

Questions and Comments

Coffee Break

Integrating Biomarkers and Multimodality Monitoring

Robert S. B. Clark, M.D.

Questions and Comments

Dinner

Session Ends

Sunday, May 20, 2012

7:30 a.m.

8:00

8:30

9:00

9:30

10:00

10:30

10:45

11:00

11:30

11:45

12:15 p.m.

12:45

1:00

1:30

Registration

Continental Breakfast

Conventional Clinical Trial Design of Multimodality Monitoring ^

Moderator: Romergryko Geocadin, M.D.

Sample Size Calculations

Yuko Palesch, Ph.D.

Can We Demonstrate the Efficacy of Monitoring?

David Zygun, M.D.

Efficacy Endpoints

Claude Hemphill III, M.D.

Patient Selection and Recruitment

Claudia S. Robertson, M.D.

Questions and Comments

Coffee Break

Alternative Clinical Trial Design ^

Moderator: Gene Sung, M.D., M.P.H.

Comparative Effectiveness Research

Andrew I. R. Mass, M.D., Ph.D.

Should we use Sliding Dichotomy?

Renee H. Martin, Ph.D.

What Surrogate End-Points are Worth Investigating?

Michael J. Souter, M.D.

What Should We Learn from the Failure of Phase III Clinical Trials in the Neurocritically ill?

Randall Chestnut, M.D.

Questions and Comments

Concluding Remarks

Jose I. Suarez, M.D. and All Attendees

Conference Adjourns

^ Presenters and moderators will have a 1-hour breakout session to refine summary statements
and ideas following their presentation.

Onsite Conference Contact

Jose I. Suarez, M.D.
Phone: 713-319-4454
Email:

Theresa Kukic
Phone: 412-207-9735
Email:

Continuing Medical Education

St. Luke's Episcopal Hospital is accredited by the Texas Medical Association to provide continuing medical education for physicians. St. Luke's designates this educational activity for a maximum of 11.75 AMA PRA Category 1 Credit(s)™. We also have made arrangements to provide an equal number of CE Credits for nurses. Physicians and nurses should only claim credit commensurate with the extent of their participation in the activity.

Sponsors(Click logo for sponsor information)

St. Luke's NeuroScience CenterDepartment of Neurology, Baylor College of Medicine

Integra FoundationNeurocritical Care Society

National Institute of Neurological Disorders and Stroke

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