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Neurology

Houston, Texas

The Cullen Building at Baylor College of Medicine.
Department of Neurology
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Thomas A. Kent, M.D.

Professor of Neurology

Chief of Neurology, Michael E. DeBakey Veterans Affairs Medical Center

Director of Stroke Research and Education

Member, Translational Biology and Molecular Medicine Graduate Program

Associate Editor, Translational Stroke Research Journal

Clinical Service Area

Neurology

Medical School

M.D., University of Kansas Medical Center, Kan.

Clinical Interests

Acute stroke therapy, diabetes and stroke, interface of psychiatry with neurological illness

Research Interests

Novel anti-thrombotic therapies for acute stroke, mechanisms of interaction between hyperglycemia and the cerebral vasculature, transcriptional events in stroke recovery, development of analytical methods for neuroimaging

Contact Information

Thomas A. Kent, M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Tel: 713-794-7393
Fax: 713-794-7786
Email:

Journal Publications (Selected out of 100)

  • Bitner BR, Marcano DC, Berlin JM, Fabian RH, Cherian L, Culver JC, et al. Antioxidant carbon particles improve cerebrovascular dysfunction following traumatic brain injury. ACS Nano. 2012;6(9):8007-14. [View journal article]
  • Kunte H, Busch MA, Trostdorf K, Vollnberg B, Harms L, Mehta RI, et al. Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas. Ann Neurol. 2012;72(5):799-806. [View journal article]
  • Mandava P, Dalmeida W, Anderson JA, Thiagarajan P, Fabian RH, Weir RU, et al. A pilot trial of low-dose intravenous abciximab and unfractionated heparin for acute ischemic stroke: Translating GP IIb/IIIa receptor inhibition to clinical practice. Transl Stroke Res. 2010;1(3):170-7. [View journal article]
  • Mandava P, Kalkonde YV, Rochat RH, Kent TA. A matching algorithm to address imbalances in study populations: application to the national institute of neurological diseases and stroke recombinant tissue plasminogen activator acute stroke trial. Stroke. 2010;41(4):765-70. [View journal article]
  • Mandava P, Kent TA. A method to determine stroke trial success using multidimensional pooled control functions. Stroke. 2009;40(5):1803-10. [View journal article]
  • Dong JF, Cruz MA, Aboulfatova K, Martin C, Choi H, Bergeron AL, et al. Magnesium maintains endothelial integrity, up-regulates proteolysis of ultra-large von Willebrand factor, and reduces platelet aggregation under flow conditions. Thromb Haemost. 2008;99(3):586-93. [View journal article]
  • Fabian RH, Perez-Polo JR, Kent TA. Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia. Am J Physiol Heart Circ Physiol. 2008;295(4):H1809-14. [View journal article]
  • Mandava P, Kent TA. Intra-arterial therapies for acute ischemic stroke. Neurology. 2007;68(24):2132-9. [View journal article]
  • Martini SR, Kent TA. Hyperglycemia in acute ischemic stroke: a vascular perspective. J Cereb Blood Flow Metab. 2007;27(3):435-51. [View journal article]
  • Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol. 2007;6(3):258-68. [View journal article]

Book Chapters and Other Publications (Selected out of 22)

  • Martini SR, Kent TA. Stroke and TIA. In: Levin GN, editor. Cardiology Secrets. 4th ed. Philadelphia: Elsevier Saunders; 2013. p. 433-443.
  • Mandava P, Krumpelman CS, Murthy SB, Kent TA. A critical review of stroke trial analytical methodology: outcome measures, study design, and correction for imbalances. In: Lapchack PA, Zhang JH, editors. Translational stroke research: From target selection to clinical trials. New York: Springer; 2012. p. 833-862.
  • Martini SR, Kent TA. Stroke and TIA. In: Levin GN, editor. Cardiology Secrets. 3rd ed. Philadelphia: Mosby; 2010. p. 355-362.
  • Mandava P, Kent TA. Metabolic disease and stroke: Fabry's disease. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic579.htm. [View electronic article]
  • Mandava P, Kent TA. Metabolic disease and stroke: homocysteinuria/homocysteinemia. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic578.htm. [View electronic article]
  • Mandava P, Kent TA. Metabolic disease and stroke: hypoglycemia/hyperglycemia. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic581.htm. [View electronic article]
  • Mandava P, Kent TA. Metabolic disease and stroke: MELAS. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic580.htm. [View electronic article]
  • Mandava P, Kent TA. Metabolic disease and stroke: methylmalonic acidemia. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic576.htm. [View electronic article]
  • Mandava P, Kent TA. Metabolic disease and stroke: proprionic acidemia. In: Lorenzo NY, Lutsep H, editors. eMedicine online neurology reference textbook. eMedicine, Inc.; 2003. Available from: http://www.emedicine.com/NEURO/topic577.htm. [View electronic article]
  • Barratt ES, Felthous A, Kent TA, Liebman MJ, Coates D. Criterion measures of aggression: Impulsive versus premediated aggression. In: Fishbein D, editor. The science treatment and prevention of antisocial behaviors: Applications to the criminal justice system. Kingston, NJ: Civic Research Institute, Inc.; 2000. p. 4.1-4.15.

Poster and Platform Presentations (Selected out of 157)

  • Barreto AD, Mandava P, Guerrero W, Shen L, Grotta JC, Kent TA. Combination argatroban and TPA for acute ischemic stroke: A matched case-control analysis. Stroke. 2014;45:AWP52.
  • Mandava P, Shah SD, Sarma AK, Dalmeida D, Kent TA. A pooled analysis indicates the promise and pitfalls of improving upon intravenous rt-PA for ischemic stroke. Stroke. 2014;45:AWP60.
  • Kent TA, Fabian RH, Marcano D, Samuel ELG, Berka V, Tsai A-L, et al. A new class of antioxidant carbon nanoparticles: Superoxide to oxygen generators. Presented at the American Neurological Association (ANA), 138th Annual Meeting in New Orleans, La. (Oct. 13-15, 2013). [View poster]
  • Mandava P, Murthy SB, Dalmeida W, Hannawi Y, Wu EY, Kent TA. Generation of a pooled outcome model for traumatic brain injury to use for prediction of potential trial success. Presented at the Neurocritical Care Society (NCS), 11th Annual Meeting in Philadelphia, Penn. (Oct. 1-4, 2013).
  • Shah S, Mandava P, Sarma AK, Kent TA. A pooled analysis identifies the potential to improve upon intravenous rt-PA. Presented at the American Neurological Association (ANA), 138th Annual Meeting in New Orleans, La. (Oct. 13-15, 2013). [Oral Presentation] [View poster]
  • Pugh MJ, Jaramillo C, Eapen B, Roman G, Kent T. Severity of traumatic brain injury and dementia in veterans from the Afghanistan and Iraq wars. Neurology. 2013;80(Meeting Abstracts 1):P03.099.
  • Pugh MJ, Jaramillo C, Eapen B, Roman G, Kent T. The nexus of traumatic brain injury and mild cognitive impairment. Neurology. 2013;80(Meeting Abstracts 1):P03.102.
  • Fabian RF, Marcano D, Samuel EL, Tour J, Kent TA. Novel carbon-based particle antioxidants in reversible hyperglycemic MCA occlusion. Stroke. 2013;44:ATP271.
  • Fabian RH, Marcano D, Samuel EL, Tour J, Kent TA. Novel carbon-based particle antioxidants in reversible hyperglycemic MCA occlusion. Stroke. 2013;44(2_MeetingAbstracts):ATP271. [View poster]
  • Mandava P, Martini S, Albright KC, Boehme AK, Martin-Schild S, Alexandrov AV, et al. Outcomes after tPA in African American women with explicit consideration of baseline factors. Stroke. 2013;44(2_MeetingAbstracts):ATP62.

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