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Neurology

Houston, Texas

The Cullen Building at Baylor College of Medicine.
Department of Neurology
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Valerie Bomben, Ph.D.

Epilepsy Research Fellow (Year 3)

Graduate School

Ph.D., University of Alabama, Birmingham, Ala.

Contact Information

Valerie Bomben, Ph.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Email:

Journal Publications

  • Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, et al. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 2014;55(2):e6-e12. [View journal article]
  • Holth JK, Bomben VC, Reed JG, Inoue T, Younkin L, Younkin SG, et al. Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. J Neurosci. 2013;33(4):1651-9. [View journal article]
  • Fabian A, Fortmann T, Bulk E, Bomben VC, Sontheimer H, Schwab A. Chemotaxis of MDCK-F cells toward fibroblast growth factor-2 depends on transient receptor potential canonical channel 1. Pflugers Arch. 2011;461(2):295-306. [View journal article]
  • Bomben VC, Sontheimer H. Disruption of transient receptor potential canonical channel 1 causes incomplete cytokinesis and slows the growth of human malignant gliomas. Glia. 2010;58(10):1145-56. [View journal article]
  • Bomben VC, Turner KL, Barclay TT, Sontheimer H. Transient receptor potential canonical channels are essential for chemotactic migration of human malignant gliomas. J Cell Physiol. 2010;226(7):1879-88. [View journal article]
  • Sahawneh MA, Ricart KC, Roberts BR, Bomben VC, Basso M, Ye Y, et al. Cu,Zn-superoxide dismutase increases toxicity of mutant and zinc-deficient superoxide dismutase by enhancing protein stability. J Biol Chem. 2010;285(44):33885-97. [View journal article]
  • Bomben VC, Sontheimer HW. Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif. 2008;41(1):98-121. [View journal article]
  • Roberts BR, Tainer JA, Getzoff ED, Malencik DA, Anderson SR, Bomben VC, et al. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol. 2007;373(4):877-90. [View journal article]
  • Weaver AK, Bomben VC, Sontheimer H. Expression and function of calcium-activated potassium channels in human glioma cells. Glia. 2006;54(3):223-33. [View journal article]

Poster and Platform Presentations (Selected out of 10)

  • Bomben VC, Holth JK, Cramer PE, Landreth GE, Noebels JL. Bexarotene decreases hyperexcitability in two mouse models with epilepsy. Program No. 534.02. 2013 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2013. Online.
  • Bomben V, Holth J, Reed J, Cramer P, Landreth G, Noebels J. Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy. Presented at the Alzheimer's Association, Houston and Southeast Texas Chapter, 7th Annual Research Symposium on Alzheimer's Disease (Sept. 12, 2013). [View poster]
  • Goldman A, Klassen T, Gu W, Zhang F, Bomben V, Chen T, et al. High resolution copy number variation of ion channel genes in epilepsy. Abstract No 2.001, 2010, American Epilepsy Society Annual Meeting, www.aesnet.org.
  • Bomben VC, Sontheimer H. TRPC1 is essential for glioma proliferation: A role for store-operated calcium entry. Program No. 521.30. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online.
  • Bomben VC, Sontheimer H. TRPC1 and store operated calcium entry in human malignant gliomas. Program No. 235.12. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online.
  • Bomben VC, Sontheimer H. Inhibition of transient receptor potential canonical channels arrests cytokinesis in human malignant glioma cells. J Neurochem. 2008;104 Suppl 1:103-4.
  • Bomben VC, Olsen ML, Sontheimer H. Interactions between brain tumors and endothelial cells. Program No. 469.1. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online.
  • Sahawneh MA, Ricart KC, Bomben VC, Estevez AG. The role of zinc-deficient superoxide dismutase in motor neuron apoptosis. Program No. 489.1. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online.
  • Bomben VC, Sontheimer H. Role of transient receptor potential canonical channels in glioma cell physiology. Presented at the Society for Neuroscience (SFN), 36th Annual Meetingin Atlanta, Ga. (Oct. 14-18, 2006).
  • Bomben VC, Sontheimer H. Transient receptor potential canonical channels in glioma cells. J Neurochem. 2006;96 Suppl 1:100.

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