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Molecular Physiology and Biophysics

2017 Seminar Archive

Master
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December 2017

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Dec. 5
Marcos Simões-Costa, Ph.D., Assistant Professor, Nancy & Peter Meinig Family Investigator in the Life Sciences in the department of Department of Molecular Biology & Genetics at Cornell University. Presenting: Gene Regulatory Control of Neural Crest Identity

Dec. 12
Philipp Gut, M.D., Team Leader in Chemical Biology, Metabolic Health Senior Specialist at Nestlé Institute of Health Science, Switzerland. Presenting: Exercise Biology in Zebrafish.

Dec. 15
John Leach - DISSERTATION - 9 a.m. Room M112 - Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Hippo Pathway Deficiency Reverses Systolic Heart Failure After Infarction. Mentor: James F. Martin, M.D., Ph.D.

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November 2017

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Nov. 2
Brandon August, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Uncharted Territory: Developing Tools to Understand Human Telomerase. Mentor: Ergun Sahin, M.D., Ph.D.

Nov. 2
Alexander Herman, Ph.D., Postdoctoral Fellow, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Unraveling the roles of KRA5" in the pathogenesis of vascular malformations. Mentor: Joshua Wythe, Ph.D.

Nov. 7
Russell DeBose-Boyd, Ph.D., Professor, Department of Biophysics and Molecular Genetics at UT Southwestern. Presenting: Novel Sensing Mechanism Governing Feedback Regulation of HMG CoA Reductase and Cholesterol Synthesis.

Nov. 9
Norman Lapin, Ph.D., Postdoctoral Associate, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Anatomical and Functional Connectomics in Mouse Models: Initial studies in the MdX Mouse. Mentor: Robia Pautler, Ph.D.

Nov. 14
Ross Poché, Ph.D., Assistant Professor, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Transcriptional Regulation of Bioenergetic Pathways Impacting Neurodevelopment

Nov. 16
Larry Scott Jr., Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Investigating the Role of NLRP3 Inflammasome Activation in Obesity-induced AF Development. Mentor: Xander Wehrens, M.D., Ph.D.

Nov. 16
Emuejevoke Olokpa, Ph.D., Postdoctoral Fellow, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Post-translational regulatory mechanisms impacting CELFJ 's role in disease. Mentor: Joel Neilson, Ph.D.

Nov. 21
David Durgan, Ph.D., Assistant Professor, Department of Anesthesiology at Baylor College of Medicine. Presenting: Examining the Role Of Gut Dysbiosis in the Development of Hypertension.

Nov. 28
Timothy McKinsey, Ph.D., Associate Professor and Associate Division Head for Translational Research School of Medicine Division of Cardiology, at University of Colorado - Denver. Presenting: Protein Acetylation in Heart Failure: The Epigenome and Beyond

Nov. 30
Nejla Yosef, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: The Phenotypic And Functional Properties Of Mouse Yolk-Sac-Derived Embryonic Macrophages. Mentor: Mary Dickinson, Ph.D.

Nov. 30
Tanya Cully, Ph.D., Postdoctoral Associate, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Triadic and Lysosomal Micro-domain Signaling in Duchenne Muscular Dystrophy. Mentor: George Rodney, Jr., Ph.D.

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October 2017

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Oct. 3
Jason Fish, Ph.D., Associate Professor, Toronto General Hospital/Research Institute (UHN). Presenting: Micro-Managing Vascular Inflammation

Oct. 10
Pumin Zhang, Ph.D., Professor, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: DNA Damage Repair and Cancer

Oct. 12
Christian Valladolid, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Determining the mode of action of the VWF A2 protein in modulating thrombosis. Mentor: Miguel Cruz, Ph.D.

Oct. 12
Shang Wang, Ph.D., Postdoctoral Associate, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Roles of the oviduct cilia in mouse reproduction Mentor: Irina Larina, Ph.D.

Oct. 17
Philip Gordts, Ph.D., Assistant Researcher, Department of Medicine at University of California, San Diego. Presenting: The Molecular Complexities of apoC-III in Triglyceride-Rich Lipoprotein Clearance that Determine Cardiovascular Risk

Oct. 19
Reem Abo-Zahrah, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Perturbation of the cytoskeletal network contributes to dystrophic muscle pathology. Mentor: George Rodney, Ph.D.

Oct. 19 - Amy Hanna, Ph.D., Postdoctoral Associate, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Mechanisms of skeletal muscle dysfunction in couplon protein myopathies Mentor: Susan L. Hamilton, Ph.D.

Oct. 24
Christine Beeton, Ph.D., Associate Professor, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Targeting Potassium Channels in Rheumatoid Arthritis

Oct. 28
James Loehr - Dissertation - Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: The Role of NADPH Oxidase 2 (NOX2) ROS in Mediating Skeletal Muscle Adaptations. Mentor: George Rodney, Ph.D.

Oct. 31
Joshua Wythe, Ph.D., Assistant Professor, Molecular Physiology & Biophysics and the Cardiovascular Research Institute at Baylor College of Medicine. Presenting: Probing the Genetic and Molecular Basis of Sporadic Brain Arteriovenous Malformations

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September 2017

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Sept. 7
Valerie Jordan, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: The Role of FREM2 and FRAS1 in the Development of Congenital Diaphragmatic Hernia. Mentor: Daryl Scott, M.D., Ph.D.

Sept. 12
Da-Zhi Wang, Ph.D., Associate Professor of Pediatrics, Harvard Medical School at Boston Children's Hospital. Presenting: miRNAs in Cardiac Remodeling and Cardiomyopathy

Sept. 14
Lele Li, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Lack of Pitx2 During Myocardial Regeneration Leads to Ventricular Fat Deposition. Mentor: James F. Martin, M.D., Ph.D.

Sept. 14
Tara Rasmussen, Ph.D., Research Associate, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: The Mouse Gyg1 Gene Disruption Develops a Fetal Cardiomyopathy. Mentor: Mary Dickinson., Ph.D.

Sept. 19
William Lagor, Ph.D., Assistant Professor, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Novel Approaches to Study Lipid and Lipoprotein Physiology

Sept. 21
Tanner Monroe, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Yap reprograms chromatin to promote cardiomyocyte renewal in adult mice. Mentor: James F. Martin, M.D., Ph.D.

Sept. 21
Nanbing (Jade) Li, Ph.D., Postdoctoral Fellow, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Autophagy regulator Tfeb in mouse cardiac development. Mentor: Mary Dickinson, Ph.D.

Sept, 28
Mussie Aray, Graduate Student, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Investigation of hearing mechanics using optical tweezers. Mentor: William Brownell, Ph.D.

Sept. 28
Elda Rueda, Ph.D., Postdoctoral Fellow, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Unlocking the latent regenerative potential of Müller glial cells in the mammalian retina. Mentor: Ross Poché, Ph.D.

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August 2017

Content

Aug. 24
John Leach, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Hippo Pathway Deficiency Reverses Systolic Heart Failure Mentor: James F. Martin, M.D., Ph.D.

Aug. 24
Yocheved Schindler, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: A Role for Hippo Signaling in Zebrafish Cardiac Development and Regeneration Mentor: James F. Martin, M.D., Ph.D.

Aug. 29
Ross Poché, Assistant Professor, Molecular Physiology & Biophysics at Baylor College of Medicine. Presenting: Transcriptional Regulation of Bioenergetic Pathways Impacting Neurodevelopment

Aug. 31 - Nejla Yosef, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: TBA Mentor: Mary Dickinson, Ph.D.

Aug. 31 - Amy Hanna, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: TBA Mentor: Susan L. Hamilton, Ph.D.

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June 2017

Content

June 6
Benoit Bruneau, Ph.D., Professor and Associate Director, Gladstone Institute of Cardiovascular Disease and Senior Investigator at Gladstone Institute. Presenting: Transcriptional Regulation of Heart Development and Chromatin Structure

June 27
Wylie Vale Honorary Lecture at 3 p.m. in Kleberg Auditorium - Ronald Evans, Ph.D., Professor and Director, Gene Expression Laboratory, Howard Hughes Medical Institute Investigator, March of Dimes Chair in Molecular and Developmental Biology at Salk Institute. Presenting: Redesigning Physiology: Can Exercise Mimetics Replace Exercise?

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May 2017

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May 16
Brandon K. Harvey, Ph.D., Tenure Track Investigator & Unit Chief, Molecular Mechanisms of Cellular Stress and Inflammation Unit at National Institutes on Drug Abuse. Presenting: Monitoring and Modulating ER Calcium Homeostasis to Understand and Treat Disease

May 22
Kit Parker, Ph.D., Tarr Family Professor of Bioengineering and Applied Physics, John A. Paulson School of Engineering and Applied Sciences at Harvard University. Presenting: Your Life as Your Lab: What Happens Before Innovation.

May 23
Ken Poss, Ph.D., James B. Duke Professor, Cell Biology at Duke University School of Medicine. Presenting: Heart Regeneration in Zebrafish

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April 2017

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April 6
Rituraj Pal, DVM, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Dynamics of Amino Acid Regulation of mTORC1: Implications for Metabolic Disorders. Mentor George Rodney, Ph.D.

April 11
Evelyn Ralston, Ph.D., Chief of the Light Imaging Section in the NIAMS Office of Science Technology at National Institutes of Health. Presenting: The Beta-Tubulin tubb6: A Novel Actor in the Muscle Microtubule Disorganization that has Been Implicated in Duchenne Muscular Dystrophy.

April 12
Ann Quick - DISSERTATION Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: The Roles of JPH2 and SPEG in the Junctional Membrane Complex in Cardiac Health and Disease Mentor: Xander Wehrens, M.D., Ph.D.

April 18
Stefan Feske, M.D., Associate Professor, Department of Pathology at New York University School of Medicine. Presenting: The Expanding Role of ORAI Channels in Immunity and Beyond

April 25
Lucas Reineke, Ph.D., Assistant Professor, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Regulation of Stress Granule Dynamics and Signaling During the Stress Response.

April 27
Amber Christenson, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Journal Article: "Autophagy maintains stemness by preventing senescence". 1st-year Student

April 27
Huanan (Frederick) Shi, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Journal Article:"Breathing control center neurons that promote arousal in mice". 1st-year Student

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March 2017

Content

March 2
Larry Scott, Jr., Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Investigating the Role of Obesity-induced NLRP3 Inflammasome Activation in AF Development. Mentor: Xander Wehrens, M.D., Ph.D.

March 2
Nanbing Li, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Ascc2 regulates cardiovascular development and proliferation during early post-implantation murine embryogenesis. Mentor: Mary Dickinson, Ph.D.

March 7
Ye Chen-Izu, Ph.D., Associate Professor, Department of Pharmacology Bioengineering and Cardiology at University of California, Davis. Presenting: Mechano-Chemo-Transduction In the Heart

March 21
Zhubo Wei, Ph.D., Assistant Professor, Houston Methodist Cancer Center at Houston Methodist Research Institute. Presenting: Identify Colorectal Cancer Driver Genes Using Mouse Model and Engineered Human Colon

March 23
Tiffany Chern, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Journal Article: "Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice". First-year Student

March 23
John Martin, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Journal Article: "Extremotolerant Tardigrade Genome and Improved Radiotolerance of Human Cultured Cells by Tardigrade-unique Protein". First-year Student

March 30
Shiva Shahrara, Ph.D., Associate Professor, Department of Medicine at University of Illinois College of Medicine at Chicago. Presenting: Developing a novel therapeutic antibody for RA treatment.

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February 2017

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Feb. 2
Alexandria Doerfler, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Targeting the Microtubule-Associated Protein Tau (MAPT) using CRISPR-Cas9. Mentor: Ergun Sahin, M.D.

Feb. 2
Amy Hanna, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Cardiac-Specific FKBP12 Deficiency Causes RyR2 Ca2+ Leak, ER Stress and a Severe Dilated Cardiomyopathy. Mentor: Susan Hamilton, Ph.D.

Feb. 14
Peter Norsk, M.D., dr. med., Senior Research Director at Baylor College of Medicine & Element Scientist at NASA, Biomedical Research & Environmental Science Division, NASA, Johnson Space Center & Center for Space Medicine, Baylor College of Medicine. Presenting: Physiological Health Challenges of Travel into Deep Space

Feb. 16
Hannah Campbell, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: The Role of Striated Muscle Preferentially Expressed Protein Kinase in the Regulation of Ryanodine Receptor 2. Mentor: Xander Wehrens, M.D, Ph.D.

Feb. 16
Yang Xiao, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Single-Cell Profiling Uncovers an Ectopic Intercellular Signaling Center in Hippo Deficient Heart. Mentor: James F. Martin, M.D., Ph.D.

Feb. 21
Robert J. Brown, Ph.D., Associate Professor, Deputy Head, pro tempore, Department of Biochemistry at Memorial University of Newfoundland. Presenting: Lipasin

Feb. 23
Vaibhav Deshmukh, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Angiomotin like 2 as an alternative Yap regulator in mice heart. Mentor: James F. Martin, M.D, Ph.D.

Feb. 23
Elda Rueda, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Mitochondrial Regulation of Retinal Progenitor Cell Proliferation. Mentor: Ross Poché, Ph.D.

Feb. 28
Merry L. Lindsey, Ph.D., Professor, Department of Physiology and Biophysics and Director, Mississippi Center for Heart Research at University of Mississippi Medical Center. Presenting: Extracellular Matrix Roles in Cardiac Wound Healing

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January 2017

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Jan. 10
Sean Wu, M.D., Ph.D., Associate Professor of Medicine (Cardiovascular Medicine) at Stanford School of Medicine. Presenting:"Development-neering” At the Crossroad of Cardiac Development and Tissue Engineering

Jan. 12
Andrew Lopez, III, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Mechanical Regulation of Cardiac Fibroblasts during Embryonic Heart Development Mentor: Irina Larina, Ph.D.

Jan. 12
Shang Wang, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Mouse Reproduction in Vivo: Oviduct, Cilia, and Sperm Mentor: Irina Larina, Ph.D.

Jan. 17 - Rui Chen, M.D., Ph.D., Associate Professor, Molecular and Human Genetics at Baylor College of Medicine. Presenting: Identify Genetic Cause of Human Retina Diseases: Opportunities and Challenges

Jan. 26
Benjamin Hall, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Something Fishy is Going On: What Has Happened to Mammalian Retinal Regeneration? Mentor: Ross Poché, Ph.D.

Jan. 26
Tara Word, Ph.D., Postdoctoral Fellow, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Screening Potential Novel Drugs for Treatment of Heart Arrhythmias in CPVT Mentor: Xander Wehrens, M.D., Ph.D.

Jan. 31
Seth Blackshaw, Ph.D., Professor of Neuroscience at Johns Hopkins. Presenting: The Functional Genomics of Retinal Development

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January 2017

Content

Jan. 10
Sean Wu, M.D., Ph.D., Associate Professor of Medicine (Cardiovascular Medicine) at Stanford School of Medicine. Presenting:"Development-neering” At the Crossroad of Cardiac Development and Tissue Engineering

Jan. 12
Andrew Lopez, III, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Mechanical Regulation of Cardiac Fibroblasts during Embryonic Heart Development Mentor: Irina Larina, Ph.D.

Jan. 12
Shang Wang, Ph.D., Postdoctoral Associate, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Mouse Reproduction in Vivo: Oviduct, Cilia, and Sperm Mentor: Irina Larina, Ph.D.

Jan. 17 - Rui Chen, M.D., Ph.D., Associate Professor, Molecular and Human Genetics at Baylor College of Medicine. Presenting: Identify Genetic Cause of Human Retina Diseases: Opportunities and Challenges

Jan. 26
Benjamin Hall, Graduate Student, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Something Fishy is Going On: What Has Happened to Mammalian Retinal Regeneration? Mentor: Ross Poché, Ph.D.

Jan. 26
Tara Word, Ph.D., Postdoctoral Fellow, Molecular Physiology and Biophysics at Baylor College of Medicine. Presenting: Screening Potential Novel Drugs for Treatment of Heart Arrhythmias in CPVT Mentor: Xander Wehrens, M.D., Ph.D.

Jan. 31
Seth Blackshaw, Ph.D., Professor of Neuroscience at Johns Hopkins. Presenting: The Functional Genomics of Retinal Development