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Physio - Pautler Lab

Houston, Texas

A BCM research lab.
Pautler Lab
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  1. Pautler, RG, Silva, AC. and Koretsky, AP. “In Vivo Neuronal Tract Tracing Using Manganese Enhanced Magnetic Resonance Imaging” Magn. Res. Med, 40:740-748. 1998.
  2. T. C.-C. Hu, RG Pautler, GA MacGowan and AP Koretsky. “Manganese MRI Enhancement of the Mouse Heart During Dobutamine Inotropy” Magn. Res. Med. 46:884-890. 2000.
  3. Pautler, RG and Koretsky, AP. “Manganese Enhanced MRI (MEMRI) Neuronal Tract Tracing in Response to Odor Stimulation in Mice”Neuroimage, Jun;16(2):441-8, 2002.
  4. Pautler, RG, Mongeau, R and Jacobs, RE. “In Vivo Tract Tracing from the Murine Striatum and Amygdala Utilizing Manganese Enhanced MRI (MEMRI)” Magn Reson Med. 2003 Jul;50(1):33-9.
  5. Ghugre, MR, Martin, M, Scadeng, M, Ruffins, S, Hiltner, T, Pautler, R, Waters, C, Readhead, C, Jacobs, R and Wood, JC. “Superiority of 3D wavelet-packet denoising in MR microscopy”. Magn Reson Imaging. 2003, Oct;21(8); 913-921.
  6. Pautler, RG and Fraser, SE. “The Year(s) of the Contrast Agent – micro-MRI in the new Millennium”, review, Curr Opin Immun, 2003 Aug;15(4):385-92.
  7. Pautler, RG. “Mouse MRI: Concepts and Applications in Physiology”, invited review, Physiology, 2004, 19:168-175.
  8. Pautler, RG. “In Vivo, Trans-synaptic Tract Tracing Utilizing Manganese Enhanced MRI (MEMRI)”, invited review, NMR in Biomedicine, 2004 Dec;17(8):595-601.
  9. Pautler, RG. Biological applications of manganese-enhanced magnetic resonance imaging. Methods Mol Med. 2006;124:365-86.
  10. Tyszka, JM, Readhead, C, Bearer, EL, Pautler, RG and Jacobs, RE. “Statistical Diffusion Tensor Histology Reveals Regional Dysmyelination Effects in the Shiverer Mouse Mutant”, Neuroimage, 2006 Feb 15;29(4):1058-65.
  11. Prince J. Kannankeril, M.D., M.S.C.I, Sanjeewa A. Goonasekera, Ph.D, Brett M. Mitchell, Ph.D., Mihail G. Chelu, M.D., M.S., Wei Zhang, M.D., Debra L. Kearney, M.D., Mariella De Biasi, Ph.D., Robia G. Pautler, Ph.D., Dan M. Roden, M.D., George E. Taffet, M.D., Robert T. Dirksen, Ph.D., Mark E. Anderson, M.D., Ph.D., and Susan L. Hamilton, Ph.D “Mice with the R176Q Cardiac Ryanodine Receptor Mutation Exhibit Catecholamine-Induced Ventricular Tachycardia”. PNAS 2006 Aug 8;103(32):12179-84.
  12. Sano, M, Helenius, K, Asakura, M, Rossi, D, Taffet, G, Hu, L, Pautler, RG, Scaglia, F, Craigen, W, Kralli, A, Mikala, T, and Schneider, M. “Menage-a-trois 1 is indispensable for the transcriptional function of PPARg coactivator 1”. Cell Metab. 2007 Feb;5(2):129-42.
  13. Smith KD, Kallhoff V, Zheng H, and Pautler RG. “In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease”. Neuroimage. 2007 May 1;35(4):1401-8.
  14. Serrano, F, Deshazer, M, Smith, K, Ananta, JS, Wilson, L and Pautler, RG. “Assessing Trans-neuronal Dysfunction Utilizing Manganese Enhanced MRI (MEMRI)”, 60:169–175, Magnetic Resonance in Medicine, 2008.
  15. Kallhoff- Munoz, V, Hu, L, Chen, X, Pautler, RG and Zheng, H “Genetic Dissection of γ-secretase Dependent and Independent Functions of Presenilin Reveals Differential Regulation of Cell Cycle Events and Neuronal Cell Death”, J Neurosci, 2008 Oct 29;28(44):11421-31.
  16. Massaad, C, Pautler, RG*, Klann, E* “Overexpression of SOD-2 Reduces Hippocampal Superoxide and Prevents Memory Deficits in a Mouse Model of Alzheimer’s Disease”. PNAS. * = equal contribution. , PNAS, 2009 Aug 11;106(32):13576-81
  17. Hu, Lingyun, Sun, Y, Villasana, Le, Paylor, RE, Klann, E and Pautler, RG “Early Changes in the Apparent Diffusion Coefficient (ADC) in a Mouse Model of Sandhoff's Disease Occur Prior to Disease Symptoms and Behavioral Deficits” Magnetic Resonance in Medicine, 2009 Nov;62(5):1175-84.
  18. Massaad, C, Pautler, RG and Klann, E. Mitochondrial Superoxide: A Key Player in Alzheimer’s Disease. Aging, 2009 Sep 14;1(9):758-61
  19. Serrano, F, Chang, A, Hernandez, C, Pautler, RG, Sweatt, JD and Klann, E NADPH Oxidase Mediates Beta-Amyloid Peptide-induced Activation of ERK in Hippocampal Organotypic Cultures, Molecular Brain, 2009 Oct 5;2(1):31
  20. Hassaan, A, Chan, B, Hartman, K, Ananta, J, Mackeyev, Y, Hu, L, Pautler, RG, Wilson, LJ, and Lee, AV “Biodistribution of Carbon Nanotubes and Fullerenols – A Novel MRI Contrast Agent” Journal of Contrast Media and Molecular Imaging, 2010 Jan 26;5(1):34-38
  21. Perez, CJ, Massaad, C, Serrano, F, Pautler, RG “MRI Detection of GFP”. Neuroimage. 2010 Apr 1;50(2):375-382
  22. Bardhan, R, Chen, W, Perez-Torres, C, Bartels, M, Huschka, R, Zhao, L, Morosan, E, Pautler, RG, Joshi, A and Halas, N “Nanoshells with Targeted Simultaneous Enhancement of Magnetic and Optical Imaging and Photothermal Therapeutic Response” Advanced Functional Materials, 9(24):3901-3909.
  23. Chen, W, Bardhan, R, Bartels, M, Perez-Torres, C. Pautler, RG, Halas,NJ and Joshi, A A Molecularly Targeted Theranostic Probe for Ovarian Cancer. Molecular Cancer Therapeutics, 2010 Apr;9(4):1028-3
  24. Bitner, BR, Danielle, DC, Matthew, L, Pautler, RG and Robertson, CS “Arginase-/- mice exhibit improved rCBF post TBI” Journal of Cerebral Blood Flow & Metabolism, 2010 Apr 7.
  25. Williams, K, Koyama, T, Schulz, D, Kaluza, G, Pautler, RG, Weisbrodt, N and Conner, M “Use of Fluoroscopy to Study In Vivo Motility in Mouse Pups” accepted, Journal of Pediatric Gastroenterology, Hepatology, and Nutrition,
  26. Masaad C, Klann, E* and Pautler, RG*. “Overexpression of SOD-2 improves axonal transport rates and cerebral blood flow in the Tg2576 Mouse model of Alzheimer’s Disease.” * = equal contribution. 2010 May 10;5(5):e10561. PlosOne
  27. Smith, K, Peetmohungi, E, Zheng, H and Pautler, RG “Tau axonal transport deficits are rescued by APP overexpression” 2010;4:11-18. Magnetic Resonance Insights.
  28. Peethumnongsin, E, Yang, L, Kallhoff-Munoz, V, Hu, L, Takashima, A, Pautler, RG and Zheng, H Convergence of Presenilin- and Tau-mediated Pathways on Axonal Trafficking and Neuronal Function, 2010 Oct 6;30(40):13409-18. J Neurosci, 2010
  29. Sharma, R, Serrano, F, Terashima, T, Chan, L and Pautler, RG “Overexpression of SOD-2 rescues axonal transport deficits in the central nervous system in diabetic mice” 2010 Oct 18;5(10):e13463., PLoS One, 2010.
  30. Smith, K and Pautler, RG “R-flurbiprofen differentially rescues axonal transport deficits in mouse models of Alzheimer’s Disease” in press, Magnetic Resonance in Medicine.
  31. Bardhan R, Chen W, Bartels M, Perez-Torres C, Botero MF, McAninch RW, Schiff R, Pautler RG, Halas NJ, Joshi A. Tracking the delivery, uptake, and distribution of multimodal therapeutic nanocomplexes targeting Breast Cancer, 2010 Nov 22. [Epub ahead of print], Nano Letters.
  32. Massaad CA, Pautler RG. Manganese-enhanced magnetic resonance imaging (MEMRI).Methods Mol Biol 2011;711:145-74.
  33. Bitner, B, Perez-Torres, CJ, Hu, Lingyun, Inoue, T and Pautler RG. Improvements in a Mouse Model of Alzheimer’s Disease through SOD2 Overexpression are Due to Functional and not Structural Alterations.Magnetic Resonance Insights, in press.