Cardiovascular Sciences Postdocs
- Dimitra Georgiou, Ph.D. My research interest is focused in the area of protein interactions and functions. RyR1 is a membrane protein and works as a nanomachine that integrates cellular signals to effectively release calcium from muscle cell sarcoplasmic reticulum to the cytoplasm. I am using molecular biology, imaging and electrophysiology approaches to shine light at interactions of RyR1 with accessory proteins and other regulating molecules that control the function of the calcium release channel.
- Irina Larina, Ph.D. I am working on visualizing and characterizing cardiodynamics and hemodynamics during early embryonic mammalian development. My research activities involve live embryo culture, confocal and multiphoton microscopy of vital fluorescent markers, advanced optical coherence tomography, image processing, and 4-D reconstruction and analysis. Successful implementation of this project will define the pumping mechanism of the mammalian heart at early stages, will reveal changes in hemodynamics as structural changes in the heart develop, and will establish a valuable tool for phenotyping mutant mice with embryonic cardiovascular defects.