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Physio - Hamilton Lab

Houston, Texas

A BCM research lab.
MPB - Hamilton Lab
not shown on screen


Corona BT, Hamilton SL, Ingalls CP. Effect of prior exercise on thermal sensitivity of malignant hyperthermia-susceptible muscle. Muscle Nerve. 2010 Aug;42(2):270-2.

Hamilton, S.L. and Serysheva, I. Ryanodine Receptor Structure: Progress and Challenges, invited minireview J Biol Chem. 2009 Feb 13; 284(7):4047-51.

Andronache, Z., Hamilton, S.L., Dirksen, R.T., and Melzer, W. A Retrograde Signal from RyR1 Alters DHP Receptor Inactivation and Limits Window Ca2+ Leak in Muscle Fibers of Y522S RyR1 knock-in Mice, Proc. Natl. Acad. Sci. USA, 2009 March; 106 (11): 4531-6. (PMID: 19246389)

Fallon, J.L., Baker, M., Xiong, L., Loy, R. E., Yang, G., Dirksen, R.T., Hamilton, S.L., and A. Quiocho, F.A., Crystal Structure of Dimeric Cardiac L-Type Calcium Channel Regulatory Domains Bridged by Ca2+•Calmodulin, Proc. Natl. Acad. Sci. USA, 2009; 106(13):5135-40. (PMID: 19279214)

Halling, D.B., Black, D.J., Yang, G., Fallon, J.L., Quiocho, F. A., Pedersen, S. E., and Hamilton S.L. Determinants in CaV1 Channels that Regulate the Ca2+ Sensitivity of Bound Calmodulin, J.Biol. Chem, 2009 July 284 (30): 20041-20051. (PMID: 19473981)

S. Boncompagni, Rossi, A., Micaroni, M., Hamilton,S.L., Dirksen,R.T., Franzini Armstrong,C., and Protasi, F. Characterization and temporal development of cores in a mouse model of malignant hyperthermia, Proc. Natl. Acad. Sci. USA, 2009; 106(51): 21996-2001. (PMID: 19966218)

Corona, B.T., Rouvier, C., Hamilton, S.L., and Ingalls, C.P. Deficiency Reduces Strength Deficits After Eccentric Contraction-Induced Injury, J Appl Physiol, 2008; 105(2):527-37.

Hoeffer, C.A., Tang, W., Santillan, A., Patterson, R.J., Martinez, L. A., Tejada-Simon, M. V., Hamilton, S.L. and Klann, E. Removal of FKBP12 Enhances mTOR-Raptor Interactions LTP, Memory, and Perseverance/Repetitive Behavior, 2008; Neuron 60(5):832-45. (PMID: 19081378)

Corona, B.T., Rouviere, C., Hamilton, S.L., and Ingalls, C.P. Eccentric Contractions Do not induce Rhabdomyolysis in Malignant Hyperthermia Susceptible Mice, J Appl Physiol. 2008 Nov; 105(5):1542-53.

Durham WJ, Aracena-Parks P, Long C, Rossi AE, Goonasekera SA, Boncompagni S, Galvan DL, Gilman CP, Baker MR, Shirokova N, Protasi F, Dirksen R, Hamilton SL. RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice, Cell 133:53-65, 2008.

Huddleston, A.T., Tang, W., Takeshima, H., Hamilton, S. L., and Klann, E. , Superoxide-induced Potentiation in the Hippocampus Requires Activation of Ryanodine Receptor Type 3 and ERK Journal of Neurophysiology, 2008; 99: 1565-1571.

Serysheva, I., Ludke, S.J., Baker, M.L., Cong, Y., Topf, M., Sali, A., Hamilton, S.L. and Chiu, W. Subnanometer Resolution Cryo-EM Based Domain Models for the Cytoplasmic Region of Skeletal Muscle RyR Channel, PNAS, in press

Long, C., Cook, L.G., Hamilton, S.L., Wu, G-Y., and Mitchell, B.M. FK506 Binding Protein 12/12.6 Depletion Increases Endothelial Nitric Oxide Synthase Threonine 495 Phosphorylation and Blood Pressure. Hypertension Jan 2007; 49(3): 569- 576.

Durham, W., Wehrens, X., Sood, S., and Hamilton, S.L. Diseases Associated with Altered Ryanodine Receptor Activity, E. Carafoli and M. Brini (eds.) Calcium Signaling and Disease, Subcell Biochem. 2007;45:273-321