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Physio - Dickinson Lab

Houston, Texas

A physician explains an X-ray image.
Mary Dickinson Lab
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In PEER-Reviewed Journals

  1. Van der Meer-de Jong, R., Dickinson, M. E., Woychik, R. P., Hetherington, C. and Hogan, B.L.M. (1990) Location of the gene involving the Small eye mutation on mouse chromosome 2 suggests homology with the human aniridia 2 (AN2) gene. Genomics 7, 270-275.
  2. Woychik, R.P., Generoso, W.M., Russell, L.B., Cain, K.T., Cacheiro, N.L.A, Bultman, S.J., Selby, P.B., Dickinson, M.E., Hogan, B.L.M. and Rutledge, J.C. (1990) Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing new mutations at the limb deformity and agouti loci. Proc. Natl. Acad. Sci. USA 87, 2588-2592.
  3. Pelton, R.W., Dickinson, M.E., Moses, H.L. and Hogan, B.L.M. (1990) In situ hybridization analysis of TGFß3 RNA expression during mouse development: comparaitive studies with TGFß1 and ß2. Development 110, 609-620.
  4. Dickinson, M.E. and McMahon, A.P. (1992) The role of the Wnt genes in vertebrate development. Curr. Opinion Gen. Devel. 2, 562-566.
  5. Frohman, M.A., Dickinson, M.E., Hogan, B.L.M. and Martin, G.R.. (1993) Mapping of Gbx- 1 to mouse chromosome 5 and Gbx- 2 to mouse chromosome 1. Mouse Genome 91, 326-328.
  6. Schrick, J.J., Dickinson, M.E., Hogan, B.L.M., Selby, P.B.and Woychik, R.P. (1995) Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in distal vertebrae of the spine. Genetics 140, 1061-1067.
  7. Dickinson, M.E., Krumlauf, R. and McMahon, A.P. (1994) Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development 120, 1453-1471.
  8. Dickinson, M.E., Selleck, M.A.J., McMahon, A.P. and Bronner-Fraser, M. (1995) Dorsalization of the neural tube by the non-neural ectoderm. Development 121, 2099-2106.
  9. Serbedzija, G.N., Dickinson M. and McMahon, A.P. (1996) Spatially and temporally restricted cell death in the Wnt-1 mutant. J. Neurobiol 31, 275-282.
  10. Jacobs, R., Ahrens, E., Dickinson, M.E. and Laidlaw, D. (1999) Towards a MicroMRI Atlas of Mouse Development, Comput Med Imaging Graph Jan-Feb 23, 15-24.
  11. Longmuir, K.J.*, Haynes, S.M.*, Dickinson, M.E.*, Waring, A.J. and Murphy, J.C. (2001) Optimization of a peptide/non-cationic lipid gene delivery system for effective microinjection into chicken embryos in vivo. (* denotes equal contribution) Mol. Therapy, 4:67-74..
  12. Dickinson, M.E., Bearman, G., Tille, S., Lansford, R. and Fraser, S.E. (2001) Multi-spectral Imaging and Linear Unmixing Adds a Whole New Dimension to Laser Scanning Fluorescence Microscopy. Biotechniques, 31: 1272-1279.
  13. Dickinson, M.E, Murray, B., Haynes, S.M., Waters, C.W. and Longmuir, K.J. (2002) Using electroporation and lipid-mediated transfection of GFP-expressing plasmids to label embryonic avian cells for vital confocal and two-photon microscopy. Differentiation, 70: 172-180.
  14. Jones, E.A.V., Crotty, D., Kulesa, P.M., Waters, C.W., Baron, M.H., Fraser, S.E., Dickinson, M.E. (2002). Dynamic In Vivo Imaging of Post Implantation Mammalian Embryos Using Whole Embryo Culture. Genesis, 34: 228-35.
  15. Dickinson, M.E., Simbuerger, E., Zimmermann, B., Waters, C.W. and Fraser, S.E. (2003) Multiphoton Spectra in Biological Samples. Journal of Biomedical Optics, 8, 329-338.
  16. Hadjantonakis, A-K, Dickinson, M.E, Fraser, S.E., and Papaioannou, V.E. (2003) Technicolour Transgenics: Imaging tools for functional genomics in the mouse. Nature Rev. Genet. 4, 613-625.
  17. Nashmi, R., Dickinson, M.E., McKinney, S., Jareb, M., Labarca, C., Fraser, S.E. and Lester, H.A.(2003) Localization, Trafficking and Resonance Energy Transfer in Functional Fluorescently Labeled alpa-4 beta-2 Nicotinic Acetylcholine Receptors. J. Neuroscience, 23, 11554-11567.
  18. Jones, E.A.V., Baron, M.H., Fraser, S.E. and Dickinson, M.E. (2004) Hemodynamic Changes During the Development of the Mammalian Vasculature, Am J Phys Heart Circ Physiol, 287, 1561-1569.
  19. Fraser, S.T., Hadjantonakis, A-K., Sahr, K.E., Willey, S., Kelly, O.G., Jones, E.A.V., Dickinson, M.E. and Baron, M.H. (2005) Using a Histone Yellow Fluorescent Protein Fusion For Tracking Endothelial Cells in ES cells and Mice, Genesis, 42: 162-171. PMC1850986
  20. Liebling, M., Forouhar, A.S., Gharib, M., Fraser, S.E. and Dickinson, M.E. (2005) 4-Dimensional Cardiac Imaging of Living Embryos via Post-Acquisition Synchronization of Nongated Slice-Sequences. Journal of Biomedical Optics, 10: 054001.
  21. Lucitti, J.L. and Dickinson, M.E. (2006) Moving Towards the Light: Using New Technology to Answer Old Questions, Pediatr Res 60: 1–5. PMC1850985
  22. Dickinson, M.E. (2006) Multimodal Imaging of Mouse Development: Tools for the Postgenomic Era. Developmental Dynamics, 235: 2386-2400.
  23. Wang, J., Hamblet, N.S., Mark, S., Dickinson, M.E., Brinkman, B.C., Segil, N., Fraser, S.E., Chen, P., Wallingford, J.B., Wynshaw-Boris, A. (2006) Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development, 133, 1767-1778.
  24. Forouhar, A.S., Hickerson, A.S., Liebling, M., Moghaddam, A., Lu, J., Tsai, H-J., Hove, J.R. Fraser, S.E., Dickinson, M.E, and Gharib, M. (2006) The embryonic vertebrate heart tube is a dynamic suction pump. Science, 312: 751-753.
  25. Liebling, M., Forouhar, A.S., Wolleschensky, R., Ankerhold, R., Zimmermann, B., Fraser, S.E., Gharib, M. and Dickinson, M.E., (2006) Rapid three-dimensional imaging and analysis of the beating embryonic heart reveals functional changes during development, Developmental Dynamics, 235: 2940-2948.
  26. Lucitti, J.L., Jones, E.A.V., Huang, C., Chen, J., Fraser, S.E. and Dickinson, M.E. (2007) Vascular Remodeling of the Yolk Sac Requires Hemodynamic Force, Development, 134: 3317-3326.
  27. Haeberle, H., Bryan, L.A., Vadakkan, T., Dickinson, M.E. and Lumpkin, E.A. (2008) Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells, PloS One, 3: e1750.
  28. Larina, I.V., Carbajal, E.F., Tuchin, V.V., Dickinson, M.E., and Larin, K.V. (2008) Enhanced OCT imaging of embryonic tissue with optical clearing, Laser Physics Letters, 5: 476-481.
  29. Goldie, L.C., Lucitti, J.L., Dickinson, M.E., and Hirschi, K.K. (2008) Retinoic acid signaling regulates the specification and function of hemogenic endothelium. Blood, 112, 3194-3204 [PMID: 18684862].
  30. Larina, I.V., Sudheendran, N., Ghosn, M., Jiang, J., Cable, A., Larin, K.V., and Dickinson, M.E. (2008) Live Imaging of Blood Flow in Mammalian Embryos using Doppler Swept Source Optical Coherence Tomography, JBO letters, 13: 060506
  31. Larina, I.V., Shen, W., Kelly, O.G., Hadjantonakis, A-K., Baron, M.H. and Dickinson, M.E. (2009) A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development, The Anatomical Record, 292: 333-341. PMC2901876
  32. Larina, I.V., Ivers, S., Syed, S., Dickinson, M.E. and Larin, K.V. (2009) Hemodynamic measurements from individual blood cells in early mammalian embryos with Doppler Swept Source OCT, Optics Letters, 34, 986-988. PMC2874199
  33. Nel-Themaat, L., Vadakkan, T.J., Wang, Y., Dickinson, M.E., Akiyama, H. and Behringer, R.R. (2009) Morphometric analysis of testis cord formation in Sox9-EGFP mice. Developmental Dynamics, 238, 1100-10. PMC2838451
  34. Poché, R.A., Larina, I.V., Scott, M.L, Saik, J.E., West, J.L. and Dickinson, M.E. (2009) The Flk1-myr::mCherry mouse as a useful reporter to characterize multiple aspects of ocular blood vessel development and disease. Developmental Dynamics, 238, 2318-26. PMC2901875
  35. Vadakkan, T.J., Culver, J., Gao, L., Anhut, T. and Dickinson, M.E. (2009) Peak multiphoton excitation of mCherry using an optical parametric oscillator (OPO). J. Fluorescence, 238, 1103-9.
  36. Larin, K.V., Larina, I.V., Liebling, M. and Dickinson, M.E. (2009) Live Imaging of Early Developmental Processes in Mammalian Embryos with Optical Coherence Tomography, J Innovative Optical Health Sciences, 2: 253-259. PMC2891056
  37. Larina, I.V., Furushima, K., Dickinson, M.E., Behringer, R.R. and Larin, K.V. (2009) Live Imaging of Rat Embryos with Doppler Swept Source Optical Coherence Tomography. J Biomed Opt 14, 050506.
  38. Fouletier Dilling, C., Wada, A., Merched-Savage, M., Lazard, Z.W., Gannon, F.H., Vadakkan, T. J., Gao, L., Hirschi, K.K., Dickinson, M.E., Davis, A.R., and Olmsted-Davis, E.A. (2009) Vessel formation is induced prior to the appearance of cartilage in BMP2-mediated heterotopic ossification. Journal of Bone and Mineral Research, 25; 1147-56.
  39. Bhat, S., Larina, I.V., Larin, K.V., Dickinson, M.E. and Liebling, M. (2009) Multiple-cardiac-cycle noise reduction in dynamic optical coherence tomography of the embryonic heart and vasculature. Optics Letters 34, 3704-6. PMC2893546
  40. Jang, C-W., Gao, L., Dickinson, M.E. and Behringer, R.R. (2010) Bmp4 expression pattern in developing hair follicles observed with a nuclear cyan fluorescent protein knock-in allele in the mouse. Int J Dev Biol., 54, 931-8.
  41. Moon J.J., Saik J.E., Poché R.A., Barbick J.L., Lee, S-H., Smith, A., Dickinson M.E., West J.L. (2010) Biomimetic hydrogels with pro-angiogenic properties. Biomaterials, 31, 3840-7.
  42. Poché, R.A., Saik, J.E., West, J.L. and Dickinson, M.E. (2010) The mouse cornea as a transplantation site for live imaging of engineered tissue constructs. Cold Spring Harbor Laboratory Protocols, Apr;2010(4):pdb.prot5416.
  43. Culver, J.C. and Dickinson, M.E. (2010) The effects of hemodynamic force on embryonic development. Microcirculation, 17, 164-78. PMC2927969
  44. Armstrong, J.J., Larina, I.V., Dickinson, M.E., Zimmer, W.E. and Hirschi, K.K. (2010) Characterization of Bacterial Artificial Chromosome Transgenic Mice Expressing Red Fluorescent Protein Substituted for the Murine Smooth Muscle Alpha Actin Gene. Genesis, 48, 457-63.
  45. Kazanis, I., Lathia, J.D., Vadakkan, T.J., Raborn, E., Wan, R., Mughal, M.R., Eckley, D.M., Sasaki, T., Patton, B., Mattson, M.P., Hirschi, K.K., Dickinson, M.E., and ffrench-Constant, C. (2010) Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals. J. Neuroscience, 30, 9771-81.
  46. Chao, W-T., Ashcroft, F., Daquinag, A.C., Vadakkan, T., Wei, Z., Zhang, P., Dickinson, M.E., and Kunz, J. (2010) Type I PIP kinase beta regulates focal adhesion disassembly by promoting beta1 integrin endocytosis. Mol. Cell. Biology, 30, 4463-79.
  47. Cabrera, R., Sha, Z., Vadakkan, T.J., Otero, J., Kriegenburg,F., Hartmann-Petersen, R., Dickinson, M.E. and Chang, E.C. (2010) Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe. Mol. Biol. Cell 21:3125-36. [EPub 2010 Jul 28]
  48. Udan, R.S. and Dickinson, M.E. (2010) Imaging Mouse Embryonic Development. In, Methods in Enzymology. P. Soriano and P. Wasserman, Eds. 476, 329-349.
  49. Saik, J.E., Gould, D.J., Watkins, E.M., Dickinson, M.E. and West, J.L. (2011) Covalently Immobilized Platelet Derived Growth Factor-BB Promotes Angiogenesis in Biomimetic Poly(ethylene glycol) Hydrogels, Acta. Biomat. 7,133-43.
  50. Gould, D.J., Vadakkan, T.J., Poché, R.A. and Dickinson, M.E. (2011) Multifractal and lacunarity analysis of microvascular morphology and remodeling. Microcirculation 18:136-151.
  51. Sudheendran, N., Syed, S.H., Dickinson, M.E., Larina, I.V. and Larin, K.V. (2011) Speckle variance OCT imaging of the vasculature in live mammalian embryos. Laser Physics Letters, 8, 247-252
  52. Syed, S.H., Larin, K.V., Dickinson, M.E. and Larina, I.V. (2011) Optical coherence tomography for high-resolution imaging of mouse development in utero. J. Biomed. Opt., 16, 046004.
  53. Asprer, J.S.T., Lee, B., Wu, C-S, Vadakkan, T.J., Dickinson, M.E., Lu, H-C and Lee, S-K. (2011) LMO4 functions as a coactivator of Neurogenin2 in the developing cortex. Development, 138, 2823-32.
  54. Garcia, M.D., Udan, R.S, Hadjantonakis, A.K. and Dickinson, M.E. (2011) Live imaging of mouse embryos. Cold Spring Harbor Laboratory Protocols, Apr 1;2011:pdb.top104.
  55. Garcia, M.D., Udan, R.S, Hadjantonakis, A.K. and Dickinson, M.E. (2011) Time-lapse imaging of post-implantation mouse embryos. Cold Spring Harbor Laboratory Protocols, Apr 1;2011: prot5595.
  56. Garcia, M.D., Udan, R.S, Hadjantonakis, A.K. and Dickinson, M.E. (2011) Preparation of post-implantation mouse embryos for imaging. Cold Spring Harbor Laboratory Protocols, Apr 1;2011: prot5594.
  57. Garcia, M.D., Udan, R.S, Hadjantonakis, A.K. and Dickinson, M.E. (2011) Preparation of rat serum for culturing mouse embryos. Cold Spring Harbor Laboratory Protocols, Apr 1;2011: prot5593.
  58. Leslie-Barbick, J.E., Saik, J.E., Gould, D.J., Dickinson, M.E. and West, J.L. (2011) The promotion of microvasculature formation in poly(ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide. Biomaterials, 32, 5782-9.
  59. Saik, J.E., Gould, D.J., Keswani, A.K., Dickinson, M.E. and West, J.L. (2011) Biomimetic Hydrogels with Immobilized EphrinA1 for Therapeutic Angiogenesis. Biomacromolecules, 12, 2615-22.
  60. Salisbury, E., Rodenberg, E., Sonnet, C., Hipp, J., Gannon, F., Vadakkan, T.J., Dickinson, M.E., Olmsted-Davis, E.A. and Davis, A.R. (2011) Sensory Nerve Induced Inflammation Contributes to Heterotopic Ossification. J. Cell Biochem. 112, 2748-58.
  61. Yoo, J., Larina, I.V., Larin, K.V., Dickinson, M.E., and Liebling, M. (2011) Increasing the field-of-view of dynamic cardiac OCT via post-acquisition mosaicism without affecting frame-rate or spatial resolution. Biomedical Optics Express, 2, 2614-2622.
  62. Zhu, Y., Li, F., Vadakkan, T.J., Zhang, M., Landua, J., Wei, W., Cridebring, D., Ma, J., Dickinson, M.E., Rosen, J.M., Lewis, M.T. and Wong, S.T.C. (2011) Coupling Oriented Hidden Markov Random Field Model with Local Clustering for Segmenting Blood Vessels and Measuring Spatial Structures in Images of Cancer Stem Cells and Tumor Microenvironment, IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2011, 352-357.
  63. Larina, I.V, Larin, K.V., Justice, M.J. and Dickinson, M.E. (2011) Optical Coherence Tomography for live imaging of mammalian development. Curr. Opin. Genet. Dev. 21, 579-84.
  64. Poché, R.A., Sharma, R., Garcia, M.D., Wada, A.M., Nolte, M.J., Udan, R.S., Paik, J.H., DePinho, R.A., Bartlett, J.D. and Dickinson, M.E. (2012) Transcription Factor FoxO1 Is Essential for Enamel Biomineralization.. PlosONE, 7,e30357.
  65. Larina, I.V., Larin, K.V., Dickinson, M.E., Liebling, M. (2012) Sequential Turning Acquisition and Reconstruction (STAR) method for four-dimensional imaging of cyclically moving structures, Biomedical Optics Express, 3, 650-660.
  66. Culver, J.C., Hoffman, J.C., Poché, R.A., Slater, J.H., West, J.L. and Dickinson, M.E. (2012) Three-Dimensional Biomimetic Patterning in Hydrogels to Guide Cellular Organization. Advanced Materials, 24,2343-8. Featured Article Frontispiece, Advanced Materials, 24, 2343.
  67. Larina, I.V., Syed, S.H., Sudheendran, S.N, Overbeek, P.A, Dickinson, M.E., Larin, K.V. (2012) Optical Coherence tomography for live phenotypic analysis of embryonic ocular structures in mouse models. Journal of Biomedical Optics, 17, 081410-4.
  68. Cuchiara, M.P., Gould, D.J., Dickinson, M.E., and West, J.L. (2012) Integration of Self-Assembled Microvascular Networks with Microfabricated Poly(ethylene glycol) Hydrogels, Advanced Functional Materials, In Press.
  69. Wat, M.J., Yu, Z., Veenma, D., Garcia, M.D., Hernandez, A., Holder, A.M., Wat, J.J., Chen, Y., Dickinson, M.E., Tibboel. D., Klein, A., Lee, B., Scott, D.A. (2012) Mouse model demonstrates that SOX7 contributes to the development of congenital diaphragmatic hernias in individuals with recurrent deletions of 8p23.1. Human Molecular Genetics, In Press.
  70. Larina, I.V., Dickinson, M.E. (2012) In vivo Imaging of the developing mouse embryonic vasculature. Meth. Mol. Biol. 872, 205-15.
  71. Bitner, B.R., Marcano, D.C., Berlin, J.M., Fabian, R.H., Cherian, L., Culver, J.C., Dickinson, M.E., Robertson, C.S., Pautler, R.G., Kent, T.A. and Tour, J.M. (2012) Carbon Particles Improve Cerebrovascular Dysfunction Following Traumatic Brain Injury. ACS Nano, In Press.
  72. Udan, R.S., Culver, J.C., and Dickinson, M.E. Advances in vasculogenesis and angiogenesis. (2012) WIREs Dev Biol , In Press.

In PEER-Reviewed Journals: