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Leal Lab

Houston, Texas

The Cullen Building at Baylor College of Medicine.
Molecular and Human Genetics - Center for Statistical Genetics
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Merry-Lynn McDonald

Merry-Lynn McDonald

Contact Information

Research Interests

I am interested in using genetic epidemiology to provide insight into complex disease. Thus far, I have analyzed both case-control and family data for several complex diseases including bipolar disorder, cardiovascular disease traits and non-syndromic hearing impairment. I am also interested in developing methods for analyzing rare-copy number variants.



View a Pubmed listing of Merry-Lynn's publications, (sort in Pubmed by date to view latest publications):

  1. Chishti MS, Lee K, McDonald ML, Hassan MJ, Ansar M, Ahmad W, et al. (2009) Novel autosomal recessive non-syndromic hearing impairment locus (DFNB71) maps to chromosome 8p22-21.3. J Hum Genet, 54 (3), 141-4.
  2. Bhatti A, Lee K, McDonald ML, Hassan MJ, Gutala R, Ansar M, et al.(2008) Mapping of a new autosomal recessive non-syndromic hearing impairment locus (DFNB45) to chromosome 1q43-q44. Clin Genet, 73 (4), 395-8.
  3. Chishti MS, Bhatti A, Tamim S, Lee K, McDonald ML, Leal SM, et al. (2008) Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families. J Hum Genet, 53 (2), 101-5.
  4. Letarte M, McDonald M, Li M, Kathirkamathamby K, Vera S, Pece-Barbara N, Kumar S.(2005) Reduced endothelial secretion and plasma levels of TGF-þ1 in Hemorrhagic patients with Hereditary Telangiectasia type 1. Cardiovascular Research.
  5. Bourdeau A, Faughnan ME, McDonald ML, Paterson AD, Wanless IR and Letarte M. (2001) Potential Role of Modifier Genes Influencing Transforming Growth Factor-B1 Levels in the Development of Vascular Defects in Endoglin Heterozygous Mice with Hereditary Hemorrhagic Telangiectasia. American Journal of Pathology, 158(6):2011-2020.

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