I am interested in using genetic epidemiology to provide insight into complex disease. Thus far, I have analyzed both case-control and family data for several complex diseases including bipolar disorder, cardiovascular disease traits and non-syndromic hearing impairment. I am also interested in developing methods for analyzing rare-copy number variants.
- Ph.D. Candidate, Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine
- MSc, Genetic Epidemiology, University of Saskatchewan
- HBSc, Biochemistry, University of Waterloo
View a Pubmed listing of Merry-Lynn's publications, (sort in Pubmed by date to view latest publications):
- Chishti MS, Lee K, McDonald ML, Hassan MJ, Ansar M, Ahmad W, et al. (2009) Novel autosomal recessive non-syndromic hearing impairment locus (DFNB71) maps to chromosome 8p22-21.3. J Hum Genet, 54 (3), 141-4.
- Bhatti A, Lee K, McDonald ML, Hassan MJ, Gutala R, Ansar M, et al.(2008) Mapping of a new autosomal recessive non-syndromic hearing impairment locus (DFNB45) to chromosome 1q43-q44. Clin Genet, 73 (4), 395-8.
- Chishti MS, Bhatti A, Tamim S, Lee K, McDonald ML, Leal SM, et al. (2008) Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families. J Hum Genet, 53 (2), 101-5.
- Letarte M, McDonald M, Li M, Kathirkamathamby K, Vera S, Pece-Barbara N, Kumar S.(2005) Reduced endothelial secretion and plasma levels of TGF-þ1 in Hemorrhagic patients with Hereditary Telangiectasia type 1. Cardiovascular Research.
- Bourdeau A, Faughnan ME, McDonald ML, Paterson AD, Wanless IR and Letarte M. (2001) Potential Role of Modifier Genes Influencing Transforming Growth Factor-B1 Levels in the Development of Vascular Defects in Endoglin Heterozygous Mice with Hereditary Hemorrhagic Telangiectasia. American Journal of Pathology, 158(6):2011-2020.