skip to content »

Molecular and Human Genetics

Houston, Texas

Department of Molecular and Human Genetics
Department of Molecular and Human Genetics
not shown on screen

Primary Faculty Appointments

Huda Zoghbi, M.D., and Hugo Bellen, D.V.M., Ph.D

Huda Zoghbi, M.D., and Hugo Bellen, D.V.M., Ph.D

Erez Aiden, Ph.D.
Assistant Professor
Integrating mathematical and physical theory with the invention of new technologies with a central focus on the study of how genomes fold.

Benjamin Arenkiel, Ph.D.
Assistant Professor
Molecular genetic studies to investigate mechanisms of neural circuit formation, function, and maintenance.

Carlos A. Bacino, M.D.
Professor
Clinical studies in patients with imprinting disorders (Angelman Syndrome), skeletal dysplasias, and genomic disorders.

David Bates, Ph.D.
Assistant Professor
Chromosome dynamics, molecular mechanisms of DNA replication, and cell cycle control in E. coli.

Arthur L. Beaudet, M.D.
Professor, Chair
Neuronal carnitine deficiency as a risk factor for autism; Prader-Willi and Angelman syndrome; genotype-phenotype correlations for CHRNA7; molecular diagnosis in the CLIA lab.

Hugo J. Bellen, D.V.M., Ph.D.
Professor
Genetic and molecular analysis of neurotransmitter release, neural development, and neuronal degeneration in Drosophila.

John W. Belmont, M.D., Ph.D.
Professor
Structural congenital heart defects including abnormalities in laterality and hypoplastic left heart syndrome; functional studies of Zic3; genetics of human immune responses; medical population genetics.

Penelope E. Bonnen, Ph.D.
Assistant Professor
Genomics, population genetics, and genetics of mitochondrial and metabolic disease.

Juan Botas, Ph.D.
Professor
Comparative analysis of pathogenic mechanisms in neurodegenerative disorders. Screens for common 'drugable' targets.

Chester Brown, M.D., Ph.D.
Associate Professor
Genetic and genomic contributions to obesity and nutrient metabolism.

C. Thomas Caskey, M.D.
Professor
The genetic basis of schizophrenia and the discovery of schizophrenia disease genes.

Chester Brown, M.D., Ph.D.

Chester Brown, M.D., Ph.D.

Rui Chen, Ph.D.
Associate Professor
Functional genomics of visual system development and diseases; High throughput technology; Bioinformatics.

Sau Wai Cheung, Ph.D., M.B.A.
Professor
Clinical Cytogenetics; Preimplantation Genetic Screening; Chromosomal Microarray Analysis (Clinical utility of aCGH).

William J. Craigen, M.D., Ph.D.
Professor
Regulation of cellular energy metabolism; mouse models of metabolic diseases.

Wei Wei Dang, Ph.D.
Assistant Professor
Our lab uses yeast replicative aging as a model, together with human primary cell lines and adult stem cells, to study evolutionarily conserved epigenetic mechanisms during aging and development of age-related cancers.

Herman A. Dierick, M.D.
Assistant Professor
Genetic and neurobiological mechanism of Drosophila aggression.

Sarah Elsea, Ph.D.
Associate Professor
Molecular and biochemical mechanisms underlying intellectual disability syndromes complicated by behavioral problems and circadian deficits.

Christine M. Eng, M.D.
Professor
Natural history, molecular genetics, and treatment of lysosomal storage disorders; genetic testing for inherited diseases.

Richard A. Gibbs, Ph.D.
Professor
Genome science, human molecular evolution, and molecular basis of inherited disease.

Brett Graham, M.D., Ph.D.
Assistant Professor
Genetics of inborn errors of metabolism; genetic models of mitochondrial disease in Drosophila and mice.

Andy Groves, Ph.D.
Professor
The development, evolution and regeneration of the inner ear.

Neil Hanchard, M.D., Ph.D.
Assistant Professor
Genetics of complex pediatric disease traits; global health genomics.

Philip J. Hastings, Ph.D.
Professor
Mechanism of amplification and genome instability in Escherichia coli and human.

Jason Heaney, Ph.D.
Assistant Professor
Testicular and colon cancer genetics, stem/progenitor cell maintenance, and mouse models of human diseases.

Christophe Herman, Ph.D.
Associate Professor
Epigenetic inheritance and phenotypic variability.

Gregory Ira, Ph.D.
Associate Professor
DNA repair, recombination and genome instability. Molecular mechanisms of mitotic DNA recombination.

Hamed Jafar-Nejad, M.D.
Assistant Professor
Contribution of protein O-glycosylation to Notch signaling, animal development and human disease.

Milan Jamrich, Ph.D.
Professor
Pattern formation in vertebrate embryos; ocular development; gene therapy.

Graeme Mardon, Ph.D. with students

Graeme Mardon, Ph.D.

Seema Lalani, M.D.
Assistant Professor
Copy number variations and diseases, congenital cardiovascular malformations, genetic causes of language/speech delay.

Suzanne M. Leal, Ph.D.
Professor
Statistical genetics; genetic epidemiology; method development; gene mapping and identification; nonsyndromic hearing loss.

Brendan Lee, M.D., Ph.D.
Professor
Developmental genetics of the skeleton and human skeletal dysplasias; development of helper-dependent adenoviral gene therapy for immune modulation, inborn errors of metabolism, and skeletal diseases; Clinical research into the diagnosis, intervention, and treatment of metabolic and skeletal diseases.

Marilyn M. Li, M.D.
Professor
Clinical application of microarray and next generation sequencing technologies in cancer research and diagnosis; leukemia- and lymphoma-associated genetic aberrations in healthy individuals; microdeletion syndromes.

Olivier Lichtarge, M.D., Ph.D.
Professor
Computational and experimental approaches to the impact of variations on protein function and network perturbations.

James R. Lupski, M.D., Ph.D.
Professor, Vice Chair
Molecular genetics of Charcot-Marie-Tooth disease and related inherited neuropathies; molecular mechanisms for human DNA rearrangements; genomic disorders; copy number variation (CNV) and disease.

Graeme Mardon, Ph.D.
Professor
Retinal cell fate determination, development, and function in Drosophila and vertebrates.

Michael L. Metzker, Ph.D.
Associate Professor
Next-generation sequencing technology development; genetic variation studies associated with ketosis-prone diabetes; methods development in HIV forensics.

Aleksandar Milosavljevic, Ph.D.
Professor
Genomics, cancer genomics, epigenomics, and bioinformatics.

Daisuke Nakada, Ph.D.
Assistant Professor
Molecular and genetic analysis of stem cell function and cancer.

David L. Nelson, Ph.D.
Professor
Human genome and disease gene analysis; fragile X syndrome; incontinentia pigmenti; complex genetics.

Philip Ng, Ph.D.
Associate Professor
Liver and lung gene therapy.

Dongsu Park, Ph.D.
Assistant Professor
Molecular and cellular biology of mesenchymal/skeletal stem cells in tissue regeneration and cancer; Stem cell imaging and tracking in living animals.

Ankita Patel, Ph.D.
Associate Professor
Clinical cytogenetics; development of new diagnostic technologies for cytogenetics.

Richard E. Paylor, Ph.D.
Professor
Behavioral analyses of mutant mouse models of developmental and neurodegenerative disorders.

David L. Nelson, Ph.D. with student

David L. Nelson, Ph.D.

Lorraine Potocki, M.D.
Professor
Clinical characterization of selected genomic disorders; medical education in genetics.

Frank Probst, M.D., Ph.D.
Assistant Professor
Generation and characterization of mouse models of human diseases; mouse models of hearing impairment; detection of small genomic inversions; familial multiple lipomatosis.

Jeffrey Rogers, Ph.D.
Associate Professor
Primate models of human disease, especially psychiatric disorders, comparative primate genomics and evolutionary genetics.

Susan M. Rosenberg, Ph.D.
Professor
Molecular mechanisms of genome instability in evolution, antibiotic resistance, and cancer.

Marco Sardiello, Ph.D.
Assistant Professor
Regulatory networks of cell metabolism and neurological disorders.

Fernando Scaglia, M.D.
Professor
Molecular bases of pediatric mitochondrial encephalomyopathies; stable isotope studies in MELAS syndrome to evaluate nitric oxide flux production and glucose kinetics; EPI-746 clinical trial for Leigh syndrome.

Christian Schaaf, M.D., Ph.D.
Assistant Professor
The genetic basis of neuropsychiatric disease and development of novel therapeutic strategies.

Daryl Scott, M.D., Ph.D.
Assistant Professor
Identifying and characterizing genes responsible for common birth defects.

Kenneth L. Scott, Ph.D.
Assistant Professor
Cancer gene discovery, pathways governing tumor metastasis and animal models for cancer.

Gad Shaulsky, Ph.D.
Professor, Director of Graduate Program
Allorecognition, evolution of sociality and functional genomics in Dictyostelium.

Chad Shaw, Ph.D.
Assistant Professor
Devising new statistical methods for genome scale data using a systems biology approach.

Joshua M. Shulman, M.D., Ph.D.
Assistant Professor
Functional genomics of Alzheimer's disease and Parkinson's disease; integrative genetic analyses in humans and Drosophila.

Pawel Stankiewicz, M.D., Ph.D.
Associate Professor
Molecular mechanisms and clinical consequences of genomic rearrangements.

V. Reid Sutton, M.D.
Associate Professor
Aicardi syndrome, Focal Dermal Hypoplasia (Goltz syndrome), skeletal dysplasias (Osteogenesis Imperfecta), and inborn errors of metabolism.

Meng Wang, Ph.D.
Assistant Professor
Systemic studies of endocrine and metabolic signaling in promoting healthy aging.

Susan M. Rosenberg, Ph.D. with students

Susan M. Rosenberg, Ph.D.

Thomas (Trey) Westbrook, Ph.D.
Associate Professor
RNAi-based strategies to cancer gene discovery; REST tumor suppressor pathway.

Lisa D. White, Ph.D.
Associate Professor
Genomic and RNA profiling using microarray and high throughput sequencing technologies to answer cancer-related questions.

Lee-Jun C. Wong, Ph.D.
Professor
Mitochondrial genetics and function in human diseases, cancer, and aging.

Fuli Yu, Ph.D.
Assistant Professor
High throughput DNA technologies; Next-Generation Sequencing (NGS) data analysis; 1000 Genomes Project

Hui Zheng, Ph.D.
Professor
Pathophysiological studies of Alzheimer’s disease pathways using mouse models.

Huda Y. Zoghbi, M.D.
Professor
Molecular basis of neurodegenerative and neurodevelopmental disorders; nervous system development.

Chenghang (Chuck) Zong, Ph.D.
Assistant Professor
Single cell analyses for tumorigenesis and stem cell differentiation.

E-mail this page to a friend