KOMP2: The BaSH Consortium
The International Knockout Mouse Consortium (IKMC), which includes the NIH-funded Knockout Mouse Project (KOMP), aims to generate functional information for every mammalian gene to inform human genome disease studies while generating mouse models for human diseases. The BaSH consortium is one of three NIH-funded KOMP2 awardees. The purpose of KOMP2 is to generate mouse strains from previously targeted ES cells (EUCOMM, KOMP) and to characterize these in a high throughput phenotyping pipeline. All phenotyping data are made publically available. ES Cells, frozen sperm and some mouse strains are also available from repositories.
The BaSH consortium is a cooperative effort between Baylor College of Medicine, the Wellcome Trust Sanger Institute (WTSI) and MRC Harwell Mary Lyon Centre. The BaSH consortium is a member of the International Mouse Phenotyping Consortium (IMPC) where the status of KOMP alleles may be found. Interest may also be registered for specific KOMP alleles.