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Molecular and Cellular Biology

Houston, Texas

Image 1: Ovulated mouse cumulus cell oocyte complex immunostained for matrix proteins hyaluronan and versican. By JoAnne Richards, Ph.D.; Image 2: By Yi LI, Ph.D.; Image 3: Mouse oocyte at meiosis I immunostained  for tubulin (red) phosphop38MAPK (green) and DNA (blue). By JoAnne Richards,  Ph.D.;  Image 4: Expanded cumulus cell ooctye ocmplex  immunostained for hyaluronan (red), TSG6 (green) and DAN (blue). By JoAnne  Richards, Ph.D.;  Image 5: Epithelial cells taken from a mouse  mammary gland were cultured in a dish and transduced with a retrovirus  expressing two genes. The green staining shows green fluorescent protein and the red  staining shows progesterone receptor expression. The nucleus of each cell is  stained blue. Photomicrograph taken at 200X magnification.  By Sandra L. Grimm,  Ph.D.; Image 6: Ovarian vasculature (red) is excluded from the granulosa cells (blue) within growing follicles (round structures); Image 7:  Ovulated mouse cumulus cell oocyte  complex immunostained for matrix proteins hyaluronan and versican. By JoAnne Richards, Ph.D.
Department of Molecular and Cellular Biology
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Secondary Graduate Faculty

Kjersti Aagaard-Tillery, M.D., Ph.D.
Assistant Professor, Department of Obstetrics and Gynecology and Molecular and Cellular Biology
Benchtop and Translational Research on the Comparative Genomics, Epigenomics, and Metagenomics in Relation to Perinatal Health and the Developmental Origins of Disease

Arthur L. Beaudet, M.D.
Chair, Department of Molecular and Human Genetics;
Professor, Departments of Molecular and Human Genetics, Pediatrics, and Molecular and Cellular Biology
Role of Genomic Imprinting in Evolution and Disease including Prader-Willi and Angelman Syndromes and Autism; Hepatocyte Gene Therapy

Sarah E. Blutt, Ph.D.
Assistant Professor, Departments of Molecular Virology and Microbiology and Molecular and Cellular Biology
Intestinal B Cell Responses To Enteric Pathogens

Juan Botas, Ph.D.
Associate Professor, Departments of Molecular and Human Genetics and Molecular and Cellular Biology
Function of Hox/Homeotic Genes

Keith Syson Chan, Ph.D.
Assistant Professor, Scott Department of Urology
Bladder Cancer Stem Cells in Invasion and Metastasis

Wah Chiu, Ph.D.
Professor, Departments of Biochemistry and Molecular Biology, Molecular and Cellular Biology, Molecular Physiology and Biophysics, and Molecular Virology and Microbiology
Structural Biology of Macromolecular Machines

Mauro Costa-Mattioli, Ph.D.
Assistant Professor, Departments of Neuroscience and Molecular and Cellular Biology
Molecular and Cellular Mechanisms of Memory

Thomas A. Cooper, M.D.
S. Donald Greenberg Professor of Pathology, Departments of Pathology and Molecular and Cellular Biology;
Alternative Splicing Regulation in Development and Disease

Lawrence A. Donehower, Ph.D.
Professor, Departments of Molecular Virology and Microbiology and Molecular and Cellular Biology
Tumor Suppressors and Mouse Cancer and Aging Models

N. Tony Eissa, M.D.
Professor, Departments of Medicine, Immunology and Molecular and Cellular Biology
Signaling Pathways for Atuophagy Associated with Innate Imminity and Cellular Regulation of Misfolded Proteins

Loning Fu, Ph.D.
Assistant Professor, Department of Pediatrics Nutrition Section
The Role of the Circadian Clock in Cancer Development and Therapy

Suzanne A.W. Fuqua, Ph.D.
Professor, Department of Medicine (Lester and Sue Smith Breast Center) and Molecular and Cellular Biology
The Role of Estrogen Receptors and Estrogen-regulated Proteins in Breast Tumor Progression

Darryl L. Hadsell, Ph.D.
Associate Professor, Departments of Pediatrics and Molecular and Cellular Biology
Molecular Pathways in the Regulation of Lactation

Richard Hurwitz, M.D.
Associate Professor, Departments of Pediatrics, Molecular and Cellular Biology, and Ophthalmology
Gene therapy, Adenoviral Transduction, Stem Cell, Retinoblastoma, Retinal Degenerative Diseases, Stargardt’s Disease

Frank Kretzer, Ph.D.
Associate Professor, Departments of Ophthalmology and Molecular and Cellular Biology
Human Neovascularization of the Retina; Pathogenesis of Retinopathy of Prematurity

Dolores J. Lamb, Ph.D.
Professor, Departments of Urology and Molecular and Cellular Biology
Genetic Basis of Male Infertility/ Androgen Receptor Mutations in Advanced Prostate Cancer

Dario Marchetti, Ph.D.
Professor, Departments of Pathology and Immunology and Molecular and Cellular Biology
Mechanisms of Brain Cancer Invasion, Angiogenesis, Metastasis and the Biology and Therapeutic Utility of Circulating Tumor Cells (CTCs)

Martin M. Matzuk, M.D., Ph.D.
Professor, Departments of Pathology, Molecular and Cellular Biology, and Molecular and Human Genetics
Transgenic Mouse Models to Study Reproduction, Oncogenesis, and Development

Nicholas Mitsiades, M.D., Ph.D.
Assistant Professor, Departments of Medicine and Molecular and Cellular Biology
Developing Novel Therapeutics for Endocrine Cancers

C. Kent Osborne, M.D.
Professor, Departments of Medicine and Molecular and Cellular Biology
Director, Lester and Sue Smith Breast Center
Director, Dan L. Duncan Cancer Center at Baylor College of Medicine
Mechanism of Resistance to ER and HER2-targeted Therapies

Stephanie A. Pangas, Ph.D.
Assistant Professor, Departments of Pathology and Immunology and Molecular and Cellular Biology
SMAD Regulation of Ovarian Cancers and Reproductive Function

Shelley Sazer, Ph.D.
Associate Professor, Departments of Biochemistry and Molecular and Cellular Biology
Eukaryotic Cell Cycle Regulation in Fission Yeast

H. David Shine, Ph.D.
Associate Professor, Departments of Neuroscience, Molecular and Cellular Biology, Center for Cell and Gene Therapy
Gene Therapy for Spinal Cord Injury

Richard N. Sifers, Ph.D.
Professor, Departments of Pathology, Molecular and Cellular Biology, and Molecular Physiology and Biophysics
Glycoprotein Folding, Quality Control, Oligosaccharides, Endoplasmic Reticulum, Conformational Disease, alpha1-Antitrypsin Deficiency, Glycobiology

Nikolai A.Timchenko, Ph.D.
Professor, Departments of Pathology and Immunology, Molecular and Cellular Biology and Huffington Center on Aging.
Role of C/EBP Proteins and RNA Binding Proteins in Liver Biology

Francis T.F. Tsai, D.Phil.
Professor, Departments of Biochemistry and Molecular Biology and Molecular and Cellular Biology
Structural Biochemistry of Molecular Chaperones and Transcription Factor Assemblies

Li-yuan Yu-Lee, Ph.D.
Professor, Departments of Medicine, Molecular and Cellular Biology, Immunology, and Program in Cellular and Molecular Biology
Signal Transduction Pathways Regulating Cell Division

Laising Yen, Ph.D.
Assistant Professor, Departments of Pathology and Immunology, Molecular and Cellular Biology
Developing RNA-based Molecular Switches for Gene Regulation and Investigating RNA Mutational Events in Cancer Transcriptome

Jason T. Yustein, M.D., Ph.D.
Assistant Professor, Pediatric Hematology-Oncology and Molecular and Cellular Biology
Insights into Molecular Pathogenesis of Pediatric Sarcomas

Hui Zheng, Ph.D.
Professor, Departments of Molecular and Human Genetics, Molecular and Cellular Biology and Neuroscience
Director, Huffington Center on Aging
Pathophysiology of Alzheimer’s Disease Using Mouse and Cellular Models

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