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Molecular and Cellular Biology

Houston, Texas

Image 1: Ovulated mouse cumulus cell oocyte complex immunostained for matrix proteins hyaluronan and versican. By JoAnne Richards, Ph.D.; Image 2: By Yi LI, Ph.D.; Image 3: Mouse oocyte at meiosis I immunostained  for tubulin (red) phosphop38MAPK (green) and DNA (blue). By JoAnne Richards,  Ph.D.;  Image 4: Expanded cumulus cell ooctye ocmplex  immunostained for hyaluronan (red), TSG6 (green) and DAN (blue). By JoAnne  Richards, Ph.D.;  Image 5: Epithelial cells taken from a mouse  mammary gland were cultured in a dish and transduced with a retrovirus  expressing two genes. The green staining shows green fluorescent protein and the red  staining shows progesterone receptor expression. The nucleus of each cell is  stained blue. Photomicrograph taken at 200X magnification.  By Sandra L. Grimm,  Ph.D.; Image 6: Ovarian vasculature (red) is excluded from the granulosa cells (blue) within growing follicles (round structures); Image 7:  Ovulated mouse cumulus cell oocyte  complex immunostained for matrix proteins hyaluronan and versican. By JoAnne Richards, Ph.D.
Department of Molecular and Cellular Biology
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Primary Graduate Faculty

Bert W. O'Malley, M.D.
Professor and Chair, Department of Molecular and Cellular Biology
Hormone Action and Gene Expression: Coactivators and Corepressors

William (B.R.) Brinkley, Ph.D.
Distinguished Service Professor, Department of Molecular and Cellular Biology,
Dean Emeritus, Graduate School of Biomedical Sciences
Factors in the Nucleus and Mitotic Apparatus Affecting Genomic Instability

Karl-Dimiter Bissig, M.D., Ph.D.
Assistant Professor, Department of Molecular & Cellular Biology and Center for Cell & Gene Therapy
Cell Based Therapy for Liver Disease

Lawrence Chan, M.B., B.S., D.Sc.
Professor, Departments of Molecular and Cellular Biology and Medicine
Diabetes, Gene Therapy, Insulin Resistance, Atherosclerosis, Lipoprotein Metabolism, Obesity

Eric C. Chang, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology (Lester and Sue Smith Breast Center)
Ras GTPase Mediated Signal Transduction and Tumor Formation

Orla M. Conneely, Ph.D.
Professor, Department of Molecular and Cellular Biology
Role of Nuclear Receptors in Transcriptional Regulation of Vertebrate Development

Austin J. Cooney, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology
Nuclear Receptor Regulation of Embryonic Stem Cell Function

Francesco J. DeMayo, Ph.D.
Professor, Department of Molecular and Cellular Biology
Molecular and Developmental Biology of the Uterus and Lung

Dean Edwards, Ph.D.
Professor, Departments of Molecular and Cellular Biology and Pathology and Immunology
Associate Director for Research Infrastructure, Dan L. Duncan Cancer Center
Executive Director, Advanced Technology Cores at BCM
Steroid Receptors in Mammary Glad Development and Breast Cancer

Xin-Hua Feng, Ph.D.
Professor, Departments of Molecular and Cellular Biology and Surgery
Proteins Modifications and Signaling Networks in Cell Growth Control, Tumorigenesis and Development

Milan Jamrich, Ph.D.
Professor, Department of Molecular and Cellular Biology
Molecular Basis of Embryonic Pattern Formation

Daoyun Ji, Ph.D.
Assistant Professor, Department of Molecular and Cellular Biology
Cellular and Systems Neurobiology of Memory Formation, Storage, and Utilization.

Michael T. Lewis, Ph.D.
Assistant Professor, Department Molecular and Cellular Biology (Lester and Sue Smith Breast Center)
Mammary Gland Development and Breast Cancer

Wei Li, Ph.D.
Associate Professor, Dan L. Duncan Cancer Center, Department of Molecular and Cellular Biology
Computational Epigenomics

Yi Li, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology (Lester and Sue Smith Breast Center)
Stem Cells, Wnt, and Breast Cancer

John P. Lydon, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology
Progesterone Signaling in Mammary Gland Development and Tumorigenesis

Michael A. Mancini, Ph.D.
Professor, Department of Molecular and Cellular Biology
High Throughput Systems Biology of Gene Regulation

Shailaja K. Mani, Ph.D.
Associate Professor, Departments of Molecular and Cellular Biology and Psychiatry and Behavioral Sciences
Molecular Mechanisms of Steroid Hormone Action in Brain Function

Sean McGuire, M.D., Ph.D.
Assistant Professor, Department of Molecular and Cellular Biology
Cross-talk between DNA Damage Response and Growth Signaling in the Cell

Daniel Medina, Ph.D.
Professor, Department of Molecular and Cellular Biology
Cellular and Molecular Events Critical for Premalignant Progression

David D. Moore, Ph.D.
Professor, Department of Molecular and Cellular Biology
Nuclear Hormone Receptors Regulate Metabolism and Cancer

Hoang Nguyen, Ph.D.
Assistant Professor, Department of Molecular and Cellular Biology
Transcriptional Regulation of Skin Epithelial Stem Cell Fate

Paul A. Overbeek, Ph.D.
Professor, Department of Molecular and Cellular Biology
Mouse Models for Human Birth Defects

Fred A. Pereira, Ph.D.
Associate Professor, Huffington Center on Aging, Departments of Otolaryngology–Head and Neck Surgery and Molecular and Cellular Biology
Co-Director,Interdepartmental Program in Cell and Molecular Biology
Signaling Pathways in Auditory Development, Aging and Cancer

Jun Qin, Ph.D.
Professor, Department of Molecular and Cellular Biology
Tumor Suppressor Signaling Networks that Maintain the Human Genome

JoAnne S. Richards, Ph.D.
Professor, Department of Molecular and Cellular Biology
Ovarian Cell Differentiation, Ovulation and Cancer

Jeffrey M. Rosen, Ph.D.
C.C. Bell Professor, Department of Molecular and Cellular Biology
Mammary Gland Development and Breast Cancer

David R. Rowley, Ph.D.
Professor, Department of Molecular and Cellular Biology
Reactive Stroma in Cancer Progression

Gayle Slaughter, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology
Training Programs for Scientists

Carolyn L. Smith, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology
Estrogen Receptors and Coregulators Define the Selectivity of Gene Expression by SERMs

Arun Sreekumar, Ph.D.
Associate Professor, Department of Molecular and Cellular Biology
Metabolomic Profiling of Cancer Progression

Robert H. Thalmann, Ph.D.
Professor, Department of Molecular and Cellular Biology and Neuroscience

Ming-Jer Tsai, Ph.D.
C.C. Bell Distinguished Service Professor, Departments of Molecular and Cellular Biology and Medicine and Program of Development
Roles of Nuclear Receptors COUP-TFs and Coregulators, SRC-2/SRC-3, in Development and Diseases

Sophia Y. Tsai, Ph.D.
Professor, Department of Molecular and Cellular Biology
COUP-TFII and Vein Identity, Angiogenesis, Diabetes and Obesity and Kidney Disease

Nancy L. Weigel, Ph.D.
Professor, Department of Molecular and Cellular Biology
Steroid Receptors and Cell signaling in Prostate and Breast Cancer

Li Xin, Ph.D.
Assistant Professor, Department of Molecular and Cellular Biology
Prostate Biology and Prostate Carcinogenesis

Jianming Xu, Ph.D.
Professor Department of Molecular and Cellular Biology
Transcriptional Control of Development and Hormonally Promoted Breast and Prostate Cancers

Xiang (Shawn) Zhang, Ph.D.
Assistant Professor, Molecular & Cellular Biology and Lester and Sue Smith Breast Center
The Role of Microenvironment in Breast Cancer Metastasis

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