Surgery and Monitoring Laboratories

The DeBakey Heart Center Animal Surgery and Monitoring Laboratories consist of fully equipped surgical suites and laboratories for large and small animals totaling approximately 1,800 square feet enabling a variety of surgical maneuvers including coronary artery occlusion and reperfusion and aortic banding in mice as well as hemodynamic monitoring units for mice.

Vivarium

This core animal facility is operated in the Section of Cardiovascular Sciences of the Department of Medicine of Baylor College of Medicine and the DeBakey Heart Center. All animals are housed in facilities under the direction of the Center for Comparative Medicine comprised of a staff of 6 veterinarians, 5 veterinary technicians, and over 70 animal husbandry personnel.

Equipment

Blood gas apparatuses, surgical tables, gas anesthesia machines and ventilators, complete monitoring equipment for Pulsed Doppler flow devices, Doppler segment-length gauges, and various pressure transducers including Statham, Millar and Konigsberg, and two INDUS Doppler signal processing workstations. The laboratories are equipped with the necessary dissecting instruments and surgical and dissection microscopes, coagulating apparatuses, defibrillating devices, data acquisition and software systems including three personal computers with scanning and imaging capabilities, three personal computers with data acquisition, storage and processing capabilities, a Macintosh IIci computer with 16 channel analog-to-digital interface, digital storage oscilloscopes, an Acuson Sequoia echocardiography unit, gamma camera and nuclear angiography equipment and a multi-isotope gamma counter. As stated above, a VisualSonics Vevo-770 echocardiogram Doppler system is now in place.

Mouse Irradiation

Mouse irradiation equipment is in the laboratory of Dr. Margaret Goodell in the Center for Cell and Gene Therapy.