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diabetes-endocrinology

Houston, Texas

Anatomy instruction at Baylor College of Medicine
Medicine/Endocrinology
not shown on screen

Jeong Kyung Lee, Ph.D.

Jeong Lee

Instructor of Medicine

One Baylor Plaza (MS: BCM185)
ABBR, Room R650
Houston, TX 77030
Tel: 713-798-6020
Fax: 713-798-4585
E-mail: jklee@bcm.edu

Education

Ph.D.: University of Tokyo, Tokyo, Japan

Postdoctoral training: Baylor College of Medicine, Houston, Texas

Research Interests

  • Islet biology
  • Insulin resistance, type 2 diabetes and the metabolic syndrome
  • Circadian pathophysiology

Recent Publications

  1. Guo B, Chatterjee S, Li L, Kim JM, Lee J, Yechoor VK, Minze LJ, Hsueh W, Ma K. The clock gene, Brain and Muscle Arnt-Like1, regulates adipogenesis via Wnt signal pathway. FASEB 2012 Aug;26(8):3453-63. PMID: 22611086
  2. Poungvarin N, Lee J, Yechoor VK, Li MV, Assavapokee T, Suksaranjit P, Thepsongwajja JJ, Saha PK, Oka K, Chan L. Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity. Diabetologia. 2012 Jun;55(6):1783-96. PMID: 22382520
  3. Lee J, Kim MS, Li R, L YV, Fang Z, Nelson D, Fu L, Moore D, Ma K, Yechoor V. Loss of Bmal1 leads to Uncoupling and Impaired Glucose-stimulated Insulin Secretion in β-cells. Islets. 2011 Nov-Dec;3(6):381-8. PMID: 22045262
  4. Yechoor V, Liu V, Paul A, Lee J, Buras E, Ozer K, Samson S, Chan L. Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. Endocrinology. 2009 Nov;150(11):4863-73. PMID: 19819964
  5. Kim DH*, Lee J*, Lee B, Lee JW. ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity. Mol Endocrinol. 2009 Oct;23(10):1556-62. PMID: 19556342 (* equally contributed)
  6. Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, Roeder RG, Lee JW. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8513-8. PMID: 19433796
  7. Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, Lee SK, Chan L, Roeder RG, Lee JW. Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19229-34. PMID: 19047629
  8. Lee S*, Lee J*, Lee SK, Lee JW. Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors. 2008 Mol Endocrinol. 2008 Jun;22(6):1312-9. PMID: 18372346 (* equally contributed
  9. S, Lee DK, Dou Y, Lee J, Lee B, Kwak E, Kong YY, Lee SK, Roeder RG, Lee JW. Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15392-7. PMID: 17021013

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