The Division of Atherosclerosis and Vascular Medicine faculty include physicians, cell biologists, molecular biologists, biochemists, biophysicists, dietitians, and clinical psychologists. Research spans clinical investigation, molecular biology, biochemistry, cell biology, molecular biophysics, genetics, organ systems, and animal models of atherosclerosis. Specific areas of research include receptor biology, angiogenesis, cellular adhesion molecules, intracellular and extracellular lipolytic enzymes, drug design, gene transfer therapy, protein structure, and gene regulation. Achievements range from the initial descriptions of critical proteins and their functions to clinical trials testing the lipid-lowering HMG-CoA reductase inhibitors (statins). These achievements have paralleled the maturation of the field of lipidology.
Today, lipidology and other specialist fields are targeting an integrative approach to atherothrombotic disease. Building on its established strengths, the Section is expanding its research interests to encompass additional risk factors. These risk factors include thrombosis, inflammation, and the posited insulin resistance syndrome.