John P. Foreyt, Ph.D.
- Director, Behavioral Medicine Research Center
Clinical Research Interests:
Coronary heart disease, or CHD is the leading cause of death of both American men and women. A healthy lifestyle, including a sensible diet, regular physical activity, and managing stress, can significantly reduce the risk factors associated with the development of CHD. Dr. Foreyt's research focuses on developing strategies for maintaining a healthy lifestyle to reduce the occurrence of CHD and other chronic diseases. Studies at the Behavioral Medicine Research Center include efforts to improve methods to reduce body weight in obese individuals, blood pressure in hypertensive patients, glucose in diabetic patients, and lipid levels in dyslipidemic patients.
Dr. Foreyt's group also works with healthy individuals, exploring strategies for keeping them healthy. Because minority groups are often at especially high risk for certain diseases, the group's work has included a focus on African-American and Mexican-American individuals. Examples of recent grants include "Cuidando el Corazon: Weight Reduction for Mexican Americans," funded by the NHLBI; "Unidos en Salud: Weight Loss for Mexican Americans, "funded by the NIDDK; "Long-Term Outcome of Obesity Treatment in Minority Women: Black American Lifestyle Intervention," funded by the NIDDK and the Office of Minority Health, and "Look Ahead: Action for Health in Diabetes" funded by NIDDK. Because obesity is the number one public health problem in our country, much of Dr. Foreyt's research deals with understanding its etiology and treating its effects. For example, his group is examining the use of very low calorie diets, nutritional supplements, different kinds of physical activity, and pharmacotherapy in the treatment of obesity. They hope that the research will lead to effective behavioral strategies that can easily be incorporated into the lifestyles of Americans, making it easier for Americans to be healthy.
- Poston WS, Foreyt JP. Sibutramine and the management of obesity. Expert Opin Pharmacother. 2004 Mar;5(3):633-42.
- Poston WSC, Reeves RS, Haddock CK, Stormer S, Balasubramanyan A, Satterwhite O, Taylor J, Foreyt JP. Weight loss in obese Mexican-Americans
treated for 1-year with orlistat and lifestyle modification. International Journal of Obesity 2003;27:1486-93.
- Chakraborty BM, Mueller WH, Reeves RS, Poston WSC, Holscher DM, Quill B, Hanis CL, Foreyt JP. Migration history, health behaviors, and cardiovascular disease risk factors in overweight Mexican American women. Ethnicity and Disease 2003;13:94-108.
- Foreyt JP, Poston WSC, McInnis K, Rippe JM (Eds). Lifestyle Obesity Management, Blackwell Publishers, Malden, Massachusetts, 2003, 304 p.
- Miles JM, Leiter L, Hollander P, Wadden T, Anderson J, Doyle M, Foreyt J, Aronne L, Klein S. Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. Diabetes Care 2002;25:1123-8.
- Pendleton VR, Goodrick GK, Poston WSC, Reeves RS, Foreyt JP. Exercise augments the effects of cognitive-behavioral therapy in the treatment of binge eating. International Journal of Eating Disorders 2002;31:172-184.
- St. Jeor ST, Peruman-Chaney S, Sigman-Grant M, Williams C, Foreyt JP. Family-based interventions for the treatment of childhood obesity. Journal of the American Dietetic Association 2002;102:640-644.
- Foreyt J P, Poston WSC. Consensus view on the role of dietary fat and obesity. American Journal of Medicine 2002;113:60S-62S.
- Jakicic JM, Clark K, Coleman E, Donnelly JE, Foreyt JP, Melanson E, Volek J, Volpe S. American College of Sports Medicine Position Stand on appropriate intervention strategies for weight loss and prevention of weight regain for adults. Medicine and Science in Sports and Exercise 2001;33:2145-56.
- Manson JE, Lewis CE, Kotchen JM, Allen C, Johnson KC, Stafanick M, Foreyt JP, Klesges R, Tinker J, Noonan E, Perri MG, Hall WD. Ethnic, socioeconomic, and lifestyle correlates of obesity in U.S. women: The women's health initiative. Clinical Journal of Women's Health 2001;1:225-34.
- Poston WSC, Pavlik VN, Hyman DJ, Ogbonnaya K, Hanis CL, Haddock CK, Hyder ML, Foreyt JP. Genetic bottlenecks, perceived racism, and hypertension risk among African Americans and first generation African immigrants. Journal of Human Hypertension 2001;15:341-51.
- Davidson MH, Hauptman J, DiGirolamo M, Foreyt JP, Halsted CH, Heber D, Heimburger DC, Lucas CP, Robbins DC, Chung J, Heymsfield SB. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomized controlled trial. Journal of the American Medical Association 1999;281:235-42.