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Section of Atherosclerosis

Houston, Texas

BCM faculty, staff and trainees are the heart of the organization.
Section of Atherosclerosis and Vascular Medicine
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Huaizhu Wu, M.D.

Positions:

Assistant Professor

Contact Information:

Phone: 713-798-4141
Fax: 713-798-4121
E-mail: hwu@bcm.tmc.edu

Basic Research Interests:

My research interest is the role of inflammation associated with dyslipidemia and obesity in the development of atherosclerosis and diabetes. Using CD11/CD18-deficient hyperlipidemic mouse model, along with in vitro or ex vivo studies, we study the involvement of CD11/CD18 integrins in atherosclerosis development, including the role of CD11/CD18 in leukocyte-leukocyte, and leukocyte-endothelial cell interaction, and the potential involvement of CD11/CD18 in modified-LDL uptake by monocytes/macrophages, a critical step in atherosclerosis development. Studies on inflammation in obesity include chemokine expression, leukocyte (T cell, macrophage) accumulation in adipose tissue, systemic leukocyte activation and their roles in obesity-related disease including atherosclerosis and diabetes.

Clinical Research Interests:

I am involved in some research related to inflammation in human obesity with human specimens such as adipose tissue, leukocytes and plasma, in the hope of identifying critical inflammatory markers that link obesity with obesity-related disease including diabetes and cardiovascular disease.

Selected Publications:

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