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BCM - Baylor College of Medicine

Giving life to possible

Clinical Trials

Did you know there is both good and bad cholesterol? (H-29111)

Volunteers are needed for a study to see if raising levels of good cholesterol and further lowering levels of bad cholesterol can save more lives and reduce the chance of having a heart attack, stroke, or other heart complications. The REVEAL study is doing this by testing a treatment called anacetrapib, a drug that has been shown to raise levels of good cholesterol and lower levels of bad cholesterol in your blood. It is known from earlier studies that anacetrapib increases levels of good cholesterol in the blood by 138 percent (more than doubling the level) and also reduces levels of bad cholesterol by 40 percent. When anacetrapib is taken along with a statin, the bad cholesterol level is reduced even further than if you just take the statin alone. Doctors hope that this will reduce the number of heart attacks, strokes and deaths.

You may be qualified if you are over 50 years old and have either a history of :

Heart attack or stroke or blockages in the arteries of your neck that required surgery or peripheral arterial disease (blockages in the arteries in your legs), diabetes mellitus with a history of chest pains requiring treatment or hospitalization.

You will receive at no cost: Study-related medication (anacetrapib or placebo), Statin medication (atorvastatin), study-related physical examinations, study-related laboratory tests, physical exams, counseling on a healthy diet and lifestyle.