S0819: Carboplatin/Paclitaxel With or Without Bevacizumab and/or Cetuximab in Stage IV or Recurrent Non-Small Cell Lung Cancer (H-25596)
S0819: A Randomized Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab With or Without Concurrent Cetuximab in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC):
This study compares the effects of cetuximab on newly diagnosed Stage IV advanced primary NSCLC or recurrent disease after previous surgery and/or irradiation. Patients are randomized to 1 of 4 groups for 6 cycles: chemotherapy and bevacizumab; chemotherapy only; chemotherapy, cetuximab, and bevacizumab; or chemotherapy and cetuximab until disease progression.
For more information:http://www.clinicaltrials.gov/ct2/show/NCT00946712