From the Labs
Houston, Texas
Volume 12, Issue 10
December 2013

Dr. David Corry discovers Toll-like receptor 4


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Pathway to asthma winds through Toll-like receptor 4

In a report that appears in the journal Science, Dr. David Corry and colleagues at BCM describe an important component of on the road to asthma– a molecule called Toll-like receptor 4 that plays a key role in prompting the innate or immediate response that drives allergic disease and asthma.

Hyperactive platelets may increase risk of heart disease in African-Americans

The road to heart disease and stroke for people of African-American descent may lead down a molecular pathway that activates platelets, the clot-forming cells of the blood, said researchers led by those from Baylor College of Medicine in Houston and Jefferson Medical College of Thomas Jefferson University in Philadelphia.

SRC-2, master molecule, sets stage for embryo implantation

Sperm must penetrate the egg for a pregnancy to result, but an equally important step is the implantation of the developing blastocyst into the endometrium – the lining of the uterus. This requires the input of the master molecule steroid receptor coactivator-2 (SRC-2), said researchers from Baylor College of Medicine in a report that appears online in the open access journal PLoS Genetics.

Fluorescent green plus Gam marks double stranded DNA breaks in bacterial and human genome

A bacterial virus protein called Gam fused to green fluorescent protein "lights up" dangerous double-stranded DNA breaks, giving scientists a new tool with which to quantify a problem that can destabilize the genome, driving both evolution and cancer, said researchers led by those from Baylor College of Medicine.

Three Baylor experts receive endocrine awards

Dr. Bert O'Malley, Ming-Jer Tsai and Sophia Tsai have all received major honors from national and international endocrinology groups.

A matter of health

Dr. Tachi Yamada's recent speech at Baylor College of Medicine defines the elements of applying discoveries to the world's ills.