Jianhua Yang, Ph.D.
Assistant Professor of Pediatrics-Hematology/Oncology
Baylor College of Medicine
Texas Children's Cancer Center
One Baylor Plaza - BCM320
6621 Fannin St., MC 3-3320
Houston, Texas 77030
Phone: 832-824-4572
Fax: 832-824-4539
E-mail: jianhuay@bcm.edu
Education
- B.S, Xinjiang University, Urumgi, China
- M.S., Harbin Medical University, Harbin, China
- Ph.D, University of Texas-Houston, Houston, Texas
- Post-Doc Fellow, Baylor College of Medicine, Houston, Texas
Research Interests
- Functional analysis of molecular targets in cancer
Selected Publications
- Huang Q, Yang J, Lin Y, Walker C, Cheng J, Liu ZG and Su B. (2004). Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nature Immunology 5:98-103.
- Yang J, Hu G, Wang S, Li Y, Martin R, Li K and Yao Z. (2003). Calcineurin/nuclear factors of activated T cells (NFAT)-activating and Immunoreceptor tyrosine-based activation motif (ITAM)-containing protein that activates calcineurin/NFAT signaling pathway. J Biol Chem 278:16797-801.
- Yang J, Lin Y, Guo Z, Cheng J, Huang J, Deng L, Liao W, Chen Z, Liu Z and Su B. (2001). The essential role of MEKK3 in TNF-induced NF-kB activation. Nature Immunology 2:620-4.
- Su B, Cheng J, Yang J and Guo Z. (2001). MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. J Biol Chem 276:14784-90.
- Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhang Y and Su B. (2000). Mekk3 is essential for early embryonic cardiovascular development. Nature Genetics 24:309-13.
- Yang J, Cheng J, Xia Y, Karin M and Su B. (2000). Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol 20:2334-42.
- Lee L, Jiang F, Nicosia SV, Yang J, Su B and Bai W. (2000). MEKK1 activating human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydoxytamoxifen in endometrial and ovarian cancer cells. Mol Endocrinol 14:1882-96.