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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Faculty M-Z

  • Marco Marcelli, Ph.D. – Associate Professor, Medicine-Endocrinology. Androgen receptor, prostate cancer transition to androgen independence.
  • Dario Marchetti, Ph.D. – Professor, Pathology. Molecular determinants of brain invasion, angiogenesis, and metastasis.
  • Martin M. Matzuk, M.D., Ph.D. – Professor, Pathology. Ovarian and testicular function and dysfunction in mammals.
  • Daniel Medina, Ph.D. – Professor, Molecular and Cellular Biology. Mammary premalignant progression, mechanism of hormone-induced protection in breast cancer.
  • Aleksandar Milosavljevic, Ph.D. – Associate Professor, Molecular and Human Genetics. Bioinformatics and comparative genomics.
  • Martha P. Mims, M.D., Ph.D. – Associate Professor, Medicine-Hematology/Oncology. Genetic risk factors for prostate cancer, role of oxidative stress in cancer risk, iron metabolism.
  • William E. Mitch, M.D. – Professor, Medicine-Nephrology. Control of protein metabolism in catabolic conditions.
  • Bhagavatula Moorthy, Ph.D. – Associate Professor, Pediatrics-Neonatology. Role and regulation of cytochrome P450 in chemical carcinogenesis and chemical atherogenesis, mechanisms of lung injury and inflammation by hyperoxia, role of transcription factors in oxidative stress and cancer.
  • Philip Ng, Ph.D. – Assistant Professor, Molecular and Human Genetics. Gene therapies for genetic diseases, liver-directed and lung-directed gene therapies using HDAd, innate and adaptive immune responses to HDAd.
  • Hoang Nguyen, Ph.D. – Assitant Professor, Molecular and Cellular Biology. Skin epithelial stem cell maintenance and lineage determination.
  • Jeffrey L. Noebels, M.D., Ph.D. – Professor, Neurology. Epilepsy, inherited diseases, ion channel genes, neural gene expression, mutational analysis.
  • Steffi Oesterreich, Ph.D. – Associate Professor, Medicine, Breast Center. Function of estrogen receptor corepressors, mechanism of scaffold attachment factor in breast cancer.
  • John S. Oghalai, M.D. – Assistant Professor, Otolaryngology. Biomechanics of auditory function, outer hair cell function, therapeutic intervention for hearing loss.
  • Bert W. O'Malley, M.D. – Professor, Molecular and Cellular Biology. Hormone action, coactivator function, eukaryotic gene expression, gene therapy, nanotechnology.
  • C. Kent Osborne, M.D. – Professor, Medicine. Mechanisms of treatment resistance in breast cancer.
  • Debananda Pati, Ph.D. – Assistant Professor, Pediatrics-Hematology/Onccology. Role of regulatory proteins of chromosome segregation RAD21 and apoptosis, immunotherapy.
  • Mary E. Paul, M.D. – Associate Professor, Pediatrics. HIV disease progression in infants and children, behavioral aspects of HIV in youth including disclosure, transmission risk reduction and adherence to HAART, complications of HIV infection.
  • Robia G. Pautler, Ph.D. – Assistant Professor, Molecular Physiology and Biophysics. MRI, gene expression, axional transport, Alzheimer's disease.
  • Richard E. Paylor, Ph.D. – Professor, Molecular and Human Genetics. Behavioral analysis of mutant mouse models of human disease.
  • Joseph F. Petrosino, Ph.D. – Assistant Professor, Molecular Virology and Microbiology, Human Genome Sequencing Center. Functional genomics of infectious disease.
  • David G. Poplack, M.D. – Professor, Pediatrics-Hematology/Oncology. Childhood leukemia; clincal pharmacology of anticancer agents in children.
  • Aleksandar Rajkovic, M.D., Ph.D. – Associate Professor, Obstetrics and Gynecology. Genomic changes in uterine and ovarian disease, reproductive genetics, biomarkers.
  • Andrew P. Rice, Ph.D. – Professor, Molecular Virology and Microbiology. HIV replication and viral pathogenesis.
  • Mothaffar F. Rimawi, M.D. – Assistant Professor, Medicine-Hematology/Oncology, Breast Center. Targeted therapy and biomarkers in breast cancer.
  • Claudia S. Robertson, M.D. – Professor, Neurosurgery. Cerebral vascular flow, brain injury, imaging, biomarkers.
  • Cliona M. Rooney, Ph.D. – Professor, Pediatrics. Immunotherapy, cytotoxic T cells, gene therapy.
  • Jeffrey M. Rosen, Ph.D. – Professor, Molecular and Cellular Biology. Hormonal regulation of mammary development and cancer, stem cells in mammary development, hormone prevention of breast cancer.
  • Susan M. Rosenberg, Ph.D. – Professor, Molecular and Human Genetics.
  • David R. Rowley, Ph.D. – Professor, Molecular and Cellular Biology. Mechanisms of reactive stroma in cancer progression.
  • Rolando E. Rumbaut, M.D., Ph.D. – Associate Professor, Medicine-Pulmonary, Pediatrics-Leukocyte Biology. Mechanisms of microvascular dysfunction in inflammation.
  • Jorge G. Salazar, M.D. – Associate Professor, Surgery and Pediatrics. Neurological protection during congenital heart surgery; less invasive approaches to congenital heart disease; systems building to maximize outcomes. Myocardial genetics and proteomics and their impact in the setting of congenital heart disease.
  • Rachel Schiff, Ph.D. – Assistant Professor, Breast Center. Breast cancer endocrine and targeted therapies.
  • Paul E. Schulz, M.D. – Associate Professor, Neurology, Neuroscience. Clinical and basic science investigations regarding neurodegenerative disorders.
  • David Sheikh-Hamad, M.D. – Associate Professor, Medicine-Nephrology. Stanniocalcin, adaptation to osmotic stress, inflammation and cardiac failure.
  • H. David Shine, Ph.D. – Associate Professor, Neurosurgery, Center for Cell and Gene Therapy. Gene therapy and nervous system repair.
  • Jason M. Shohet, M.D., Ph.D. – Assistant Professor, Pediatrics-Hematology/Oncology. Molecular biology of tumor cells
  • Richard N. Sifers, Ph.D. – Associate Professor, Pathology. Post-translational checkpoints, ER-associated glycoprotein degradation, pathogenesis.
  • Carolyn L. Smith, Ph.D. – Associate Professor, Molecular and Cellular Biology. Negative regulation of estrogen receptor function and gene expression, molecular pharmacology of steroid receptors, mechanisms of action of coactivators and corepressors, Tamoxifen resistance in breast cancer, estrogen receptor-based therapies for bladder cancer.
  • David M. Spencer, Ph.D. – Associate Professor, Immunology. Prostate cancer progression, immuno-gene therapy, development and application of conditional signaling molecules, especially chemically induced dimerization (CID).
  • John W. Swann, Ph.D. – Professor, Pediatric-Neurology. Molecular mechanisms of hearing deficits, early-life seizures, gene profiling of epilepsy.
  • George E. Taffet, M.D. – Associate Professor, Medicine. Aging and cardiovascular function, arterial rigidity, mouse models.
  • Sundararajah Thevananther, Ph.D. – Associate Professor, Pediatrics-Gastroenterology. Molecular mechanisms of liver regeneration.
  • Qiang Tong, Ph.D. – Assistant Professor, Pediatrics, Medicine, Molecular Physiology and Biophysics. Molecular mechanism of life span extension by caloric restriction, adipose formation and function during obesity and diabetes, muscle, heart and liver metabolism during obesity and diabetes.
  • Francis T.F. Tsai, D.Phil. – Assistant Professor, Biochemistry. Structural and mechanistic basis of human diseases.
  • David J. Tweardy, M.D. – Professor, Medicine-Infectious Disease. Innate immunity, signal transducer and activator of transcription (STAT) protein structure and function focusing on Stat3.
  • Ignatia B. Van den Veyver, M.D. (Co-director) – Associate Professor, Obstetrics and Gynecology, Molecular and Human Genetics. Epigenetics and nutrition in development, imprinting in placenta and hydatidiform moles, developmental genetic disorders (Aicardi syndrome, Goltz syndrome).
  • James Versalovic, M.D., Ph.D. – Associate Professor, Pathology. Probiotics and human microbiome, intestinal inflammation and innate immunity, monocyte-macrophage biology.
  • K. Vinod Vijayan, Ph.D. – Assistant Professor, Medicine-Thrombosis. Serine/Threonine phosphatases in platelet and endothelial cell activation.
  • Lisa L. Wang, M.D. – Assistant Professor, Pediatrics-Hematology/Oncology. Molecular basis of osteosarcoma, RECQL4, Rothmund-Thomson syndrome.
  • Rongfu Wang, Ph.D. – Professor, Pathology, Center for Gene Therapy. Cancer immunology, inflammation, immune regulation.
  • Xander H. T. Wehrens, M.D., Ph.D. – Associate Professor, Molecular Physiology and Biophysics, Medicine-Cardiology. Molecular mechanisms and mouse models of cardiac arrhythmias and heart failure, intracellular calcium homeostasis, new drug development.
  • Nancy L. Weigel, Ph.D. – Professor, Molecular and Cellular Biology. Coactivators and androgen receptors in prostate cancer, vitamin D receptor target genes.
  • Juliet A. Wendt, M.D. – Assistant Professor, Radiology. Multimodality molecular imaging with radionuclides and optical agents.
  • John H. Wilson, Ph.D. – Professor, Biochemistry and Molecular Biology. Stability of triplet repeat sequences and the basis of dynamic mutations in cell and mice, and gene-based therapy of retinitis pigmentosa in mouse models.
  • Matthew H. Wilson, M.D., Ph.D. – Assistant Professor, Medicine-Nephrology. Transposons and gene therapy for renal diseases.
  • Lee-Jun C. Wong, Ph.D. – Professor, Molecular and Human Genetics. Genetics and pathogenic mechanism of mitochondrial disorders.
  • Jianhua Yang, Ph.D. – Assistant Professor, Pediatrics. Functional analysis of molecular targets in cancer.
  • Qitzi (Cathy) Yao, M.D., Ph.D. – Associate Professor, Surgery-Vascular Surgery. HIV vaccine development, pancreatic cancer vaccine and immunotherapy.
  • Li-Yuan Yu-Lee, Ph.D. – Professor, Medicine, Immunology, Allergy and Rheumatology. Immune and inflammatory responses and regulation, motitic kinases in cell cycle regulation, cytokinesis and aneuploidy, cell migration and metastasis.
  • Lynn Zechiedrich, Ph.D. – Associate Professor, Molecular Virology and Microbiology. Drug resistance, genetic alterations, DNA topoisomerase function.
  • Pumin Zhang, Ph.D. – Associate Professor, Molecular Physiology and Biophysics. Cell cycle regulation, myogenesis, lens development, rhabdomyosarcoma.
  • Biao Q. Zheng, M.D., Ph.D. – Associate Professor, Immunology. Molecular biology of immunosenescence, autoimmunity.
  • Hui Zheng, Ph.D. – Professor, Molecular and Human Genetics, Huffington Center on Aging. Mouse model studies of Alzheimer's disease focusing on the amyloid precursor protein and presenilins.
  • Huda Y. Zoghbi, M.D. – Professor, Molecular and Human Genetics. Pathogenesis of neurodegenerative diseases such as ataxias, Rett syndrome, MECP2 duplication disorders, autism, cerebellar and brain stem development, mouse models.

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