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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Faculty A-L

  • Anne E. Anderson, M.D. – Assistant Professor, Pediatrics. Signal transduction mechanisms in epilepsy, potassium channels, MAPK.
  • Nabil M. Ahmed, M.D. – Assistant Professor, Pediatrics-Hematology/Oncology. Immunotherapy for Solid Tumors.
  • Roberto C. Arduino, M.D. – Professor, Internal Medicine-Infectious Disease. HIV treatment strategies and new antiretroviral drugs.
  • Robert L. Atmar, M.D. – Associate Professor, Medicine. Respiratory viruses, enteric viruses, vaccine biology.
  • Ashok Balasubramanyam, M.D. – Associate Professor, Medicine. Diabetes, molecular pathology, mouse models, clinical trials.
  • Christie M. Ballantyne, M.D. – Professor, Medicine. Inflammation, vascular disease, molecular genetics, mouse models, genomics, proteomics.
  • Arthur L. Beaudet, M.D. – Professor, Molecular and Human Genetics. Epigenetics, autism, microarrays, halotype analysis, Prader-Willi syndrome.
  • David H. Berger, M.D. – Professor, Surgery. Colon cancer, molecular mechanisms, TGFb.
  • Susan M. Blaney, M.D. – Professor, Pediatrics-Hematology/Oncology. Novel therapies for pediatric cancer.
  • Catherine M. Bollard, M.B. Ch.B. – Assistant Professor, Pediatrics-Hematology/Oncology. Cell and gene therapy, developing immunotherapies for viral and malignant diseases.
  • Malcolm K. Brenner, M.B., Ch.B., Ph.D. – Professor, Medicine and Pediatrics, Center for Cell and Gene Therapy. Cell and gene therapy of cancer.
  • William Brownell, Ph.D. – Professor, Otolaryngology. Mechanics of hearing, molecular basis of cochlear outer hair cell function.
  • F. Charles Brunicardi, M.D. – Professor, Surgery. Pancreatic islet physiology and transplantation, hormone regulation of blood sugar levels.
  • Douglas G. Burrin, Ph.D. – Associate Professor, Pediatrics. Nutritional and hormonal regulation of neonatal intestinal growth and function.
  • Janet S. Butel, Ph.D. – Professor, Molecular Virology and Microbiology. SV40 and cancer, SV40 pathogenesis, SV40 variants, hamster models.
  • Keith S. Chan, Ph.D. – Assistant Professor, Urology and Molecular and Cellular Biology.
  • Lawrence C. B. Chan, M.B., D.Sc. – Professor, Medicine-Endocrinology. Molecular mechanisms of dyslipidemia and diabetes, RNA editing, apolipoproteins, atherosclerosis.
  • Jenny C. Chang, M.D. – Associate Professor, Medicine, Breast Center. Molecular profiling of therapeutic drug sensitivity, breast cancer stem cells.
  • Johnny (Changyi) Chen, M.D., Ph.D. – Professor, Vascular Surgery. Vascular disease and vascular biology, vascular tissue engineering and stem cells, vascular vaccines, pancreatic cancer.
  • Patricia Chevez-Barrios, M.D. – Assistant Professor, Pathology and Ophthalmology. Retinoblastoma biology and targeted therapies.
  • Murali M. Chintagumpala, M.D. – Professor, Pediatrics. Clinical research in brain tumors, retinoblastoma and wilms tumor.
  • Margaret E. Conner, Ph.D. – Associate Professor, Molecular Virology and Microbiology. Rotovirus pathogenesis, mucosal immunity, animal models.
  • Thomas A. Cooper, M.D. – Professor, Pathology. Pathogenesis of myotonic dystrophy, pre-mRNA splicing and human disease, developmental regulation of alternative splicing, mouse models.
  • David B. Corry, M.D. – Associate Professor, Medicine-Pulmonary. Asthma, cytokine receptors.
  • Farhad R. Danesh, M.D., FASN – Associate Professor, Medicine-Nephrology. RhoA and stem cell regulation in kidney diseases.
  • William J. Craigen, M.D., Ph.D. – Associate Professor, Molecular and Human Genetics. Energy metabolism, mitochondrial function, transgenic models.
  • John A. Dani, Ph.D. – Professor, Neuroscience. Learning/memory dysfunction, addiction, therapeutic drug analysis.
  • Alan R. Davis, Ph.D. – Associate Professor, Pediatrics. Osteoblast stem cell, recruitment, function, differentiation; tissue engineering.
  • Elizabeth A. Davis, Ph.D. – Assistant Professor, Pediatrics. Tissue engineering, gene therapy, BMP2, spinal fusion.
  • Mariella De Biasi, Ph.D. – Associate Professor, Neuroscience. Neurobiology of addiction, mouse models.
  • Francesco J. DeMayo, Ph.D. – Professor, Molecular and Cellular Biology. Molecular regulation of cell differentiation in normal and cancerous lung and uterus, progesterone, mouse models.
  • Mary E. Dickinson, Ph.D. – Assistant Professor, Molecular Physiology and Biophysics. Hemodynamic forces in vascular development and remodeling.
  • Lawrence A. Donehower, Ph.D. – Professor, Molecular Virology and Microbiology. p53 in cancer and aging, genetic alterations in osteosarcomas, Wip1 function and chemotherapy.
  • Jing-Fei Dong, M.D., Ph.D. – Associate Professor, Medicine-Thrombosis. Platelets and ligands in hemostasis and thrombosis.
  • Rachelle S. Doody, M.D., Ph.D. – Professor, Neurology. Alzheimer disease progression, modeling, treatment, methodology.
  • Gianpietro Dotti, M.D. – Assistant Professor, Medicine, Center for Cell and Gene Therapy. Immunotherapy and T cell therapy of human malignancies.
  • N. Tony Eissa, M.D. – Associate Professor, Medicine-Pulmonary. Airway inflammation, iNOS, ubiquitination, mouse models of asthma.
  • Mark L. Entman, M.D. – Professor, Medicine-Cardiovascular Science. Molecular mechanisms of cardiac injury and repair, chemokines, progenitor cells.
  • Mary K. Estes, Ph.D. (Co-Director) – Professor, Molecular Virology and Microbiology. GI virus-host interactions, pathogenesis and immunity, molecular mechanisms.
  • Xin-Hua Feng, Ph.D. – Associate Professor, Surgery. Proteins modifications and signaling mechanisms in cell growth control, tissue differentiation and tumorigenesis, TGFß/SMAD signaling and human diseases, protein phosphatases, ubiquitination, sumoylation and proteasome-dependent degradation.
  • George D. Ferry, M.D. – Professor, Pediatrics. Inflammatory bowel disease.
  • Milton J. Finegold, M.D. – Professor, Pathology. Molecular and genetic basis for liver cancer, host-bacterial interactions in inflammatory bowel disease.
  • Aaron E. Foster, Ph.D. – Assistant Professor, Pediatrics-Hematology/Oncology, Center for Cell and Gene Therapy. Identification and immunotherapeutic targeting of cancer ctem cells.
  • Michael J. Friedlander, Ph.D. – Professor, Neuroscience. Calcium and synaptic transmission.
  • Suzanne A. W. Fuqua, Ph.D. – Professor, Medicine, Breast Center. Hormone receptors, hormone responsiveness, gene expression profiling, mutant ER, metastasis, predictive markers.
  • M. Waleed Gaber, Ph.D. – Associate Professor, Pediatrics. Animal imaging of microvascular changes caused by tumor and radiotherapy.
  • Richard A. Gibbs, Ph.D. – Professor, Molecular and Human Genetics. Genomic sequencing, haplotype maps, physical mapping of genomes.
  • Margaret A. Goodell, Ph.D. – Associate Professor, Pediatrics, STaR Center, Center for Cell and Gene Therapy. Stem cell function and molecular characterization, muscle-derived hematopoeitic stem cells.
  • Stephen M. Gottschalk, M.D. – Associate Professor, Pediatrics, Immunology. Immunotherapy for malignancies and viral associated diseases.
  • Brett H. Graham, M.D., Ph.D. – Assistant Professor, Molecular and Human Genetics. Models of mitochondrial disease in fly and mouse.
  • David Y. Graham, M.D. – Professor, Medicine-Gastroenterology. Acid peptic diseases, gastrointestinal effects of non-steroidal anti-inflammatory drugs (NSAIDs), Helicobacter pylori, viral gastroenteritis.
  • Xinfu Guan, Ph.D. – Assistant Professor, Pediatrics-Nutrition. Cellular action and signaling network of glucagon-like peptide receptors (GLP-1R and GLP-2R).
  • Susan L. Hamilton, Ph.D. – Professor, Molecular Physiology and Biophysics. Molecular mechanisms of ryandoine receptor mutations, malignant hypertheria, congenital arrhythmias.
  • Michael Heggeness, M.D., Ph.D. – Professor, Orthopedic Surgery. Pathophysiology of the spine during degenerative disease states.
  • Helen E. Heslop, M.D., M.B., Ch.B. – Professor, Medicine, Center for Cell and Gene Therapy. Adoptive immunotherapy, lymphoproliferative disorders.
  • Susan G. Hilsenbeck, Ph.D. – Professor, Breast Center, Medicine, Hematology-Oncology. Design and statistical analysis of translational experiments and clinical trials.
  • Karen K. Hirschi, Ph.D. – Associate Professor, Pediatrics. Molecular biology of vascular development, stem cells and neovascularization.
  • Terzah M. Horton, M.D., Ph.D. – Assistant Professor, Pediatrics-Hematology/Oncology. Developing new treatment therapies for childhood leukemias and lymphomas.
  • Richard L. Hurwitz, M.D. – Associate Professor, Pediatrics/Hematology-Oncology. Gene therapy, retinoblastoma, retinal degeneration.
  • Michael M. Ittman, M.D., Ph.D. – Professor, Pathology. Molecular genetics of prostate cancer, fibroblast growth factors, BPH.
  • Joanna L. Jankowsky, Ph.D. – Assistant Professor, Neuroscience. Pathogenesis and treatment of Alzheimer’s disease.
  • Monica Justice, Ph.D. – Associate Professor, Molecular and Human Genetics. Forward genetics, insertional mutagenesis, leukemia genes and susceptibility.
  • Saul J. Karpen, M.D., Ph.D. – Associate Professor, Pediatrics/Liver Center. Molecular mechanisms of cholestasis, nuclear receptors, hepatobiliary transporter genes.
  • Wendy A. Keitel, M.D. – Associate Professor, Molecular Virology and Microbiology. Infectious diseases, prevention of respiratory infections, vaccines, host response.
  • Thomas A. Kent, M.D. – Professor, Neurology. Hyperglycemia in stroke, molecular interactions in synaptic plasticity.
  • Farrah Kheradmand, M.D. – Associate Professor, Medicine-Pulmonary. Immune cells and lung disease, matrix metalloproteinases, cytokine function.
  • Jason T. Kimata, Ph.D. – Assistant Professor, Molecular Virology and Microbiology. HIV replication and pathogenesis; HIV model development.
  • Mark W. Kline, M.D. – Professor and Chief, Pediatrics-Retrovirology. International pediatric HIV/AIDS care and treatment.
  • Thomas R. Kosten, M.D. – Professor, Psychiatry and Neuroscience. Developing medications and vaccines for addictions.
  • Jeanette Kunz, Ph.D. – Assistant Professor, Molecular Physiology and Biophysics. Regulation of cell migration, adhesion and invasion, phosphoinositide signaling.
  • H. Daniel Lacorazza, Ph.D. – Assistant Professor, Pathology. Developmental immunology and hematopoiesis, transcription factor ELF-4, stem cell maintenance.
  • Dolores J. Lamb, Ph.D. – Professor, Urology. Molecular basis of male infertility, mismatch repair, transgenic insertional mutagenesis.
  • Adrian V. Lee, Ph.D. – Associate Professor, Medicine, Breast Center. IGF1 and steroid hormones in mammary gland development and cancer, gene function, specific inhibitors of IGF1.
  • Brendan Lee, M.D., Ph.D. – Professor, Molecular and Human Genetics. Genetic pathways that specify development and homeostasis, translational studies of skeletal development, therapy for metabolic diseases.
  • Ann M. Leen, Ph.D. – Assistant Professor, Pediatrics-Hematology/Oncology. T cell immunotherapy for viruses and cancer.
  • Mimi Leong, M.D. – Assistant Professor, Plastic Surgery Division and Pediatrics-Leukocyte Biology. The role of macrophages in diabetic wound healing.
  • Seth P. Lerner, M.D. – Professor, Urology. Bladder cancer, estrogen receptor targeted therapy.
  • Yi Li, Ph.D., M.S. – Assistant Professor, Molecular and Cellular Biology, Breast Center. Stem cells and breast cancer, Wnt signaling and cell fate.
  • Peter H. Lin, M.D. – Associate Professor, Vascular Surgery. Endovascular treatment outcome and endovascular device development. Vascular disease progression and pathogenesis of venous thrombotic disease.
  • James R. Lupski, M.D., Ph.D. – Professor, Molecular and Human Genetics. Genomic disorders, gene dosage and recombination.

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