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A Cocaine Vaccine
The drug is excreted without generating the euphoria or energy cocaine addicts expect. Kosten's study, published in the Archives of Psychiatry, showed that the vaccine blocks the effect in 38 percent of cocaine-users who received it. It's not a panacea, but the study shows the drug can work in addictive disease. He plans a larger study with the current vaccine and a research plan to improve the vaccine itself. "The results of this study represent a promising step toward an effective medical treatment for cocaine addiction," said Dr. Nora Volkow, director of the National Institute on Drug Abuse. "Provided that larger follow-up studies confirm its safety and efficacy, this vaccine would offer a valuable new approach to treating cocaine addiction, for which no FDA-approved medication is currently available." |
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Volume 5, Issue 1, Winter 2009 |
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| Last modified: December 7, 2009 |
A vaccine that calls the body's immune system to arms against invading cocaine molecules may prove an important tool in the fight against addiction. "The concept works," said Dr. Thomas R. Kosten, professor of psychiatry and behavioral sciences at Baylor College of Medicine. "The vaccine provokes the body to make antibodies. The antibodies bind to the cocaine, preventing it from leaving the bloodstream."