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Mind Games
"This may be the first time a physical signature for a personality disorder has been identified," said P. Read Montague, Ph.D., Professor of Neuroscience and Director of the BCM Brown Foundation Human Neuroimaging Laboratory at BCM. In the study, directed by Brooks King-Casas, Ph.D., Assistant Professor of Neuroscience and Psychiatry & Behavioral Sciences, people with borderline personality disorder played a "trust" game with healthy people. The fMRI scans showed that a portion of the brain lights up only when people with borderline personality send money to the other player. However, that same portion lights up in normal people both when they send money and when they receive it. Measuring this kind of activity could result in a diagnostic tool or even a way to measure the effectiveness of treatment some day, said King-Casas. |
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Volume 4, Issue 3, Winter 2008 |
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| Last modified: December 29, 2008 |
Using a functional magnetic resonance imaging (fMRI) machine, a computer game and specialized software, BCM researchers have identified a brain malfunction in people with borderline personality disorder, a serious and common mental illness. These individuals frequently have unstable relationships, fly into rages inappropriately, or become depressed and cannot trust the actions and motives of other people.