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Department of Pharmacology

Houston, Texas

BCM students are involved in research.
Pharmacology
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Ph.D. Graduates of the Pharmacology Department

Anderson, Michael W., Ph.D. (1981) Thesis title: The effects of thioacetamide on preribosomal RNA gene expression and the metabolism of nucleolar chromatin protein A24. Advisor: Dr. Harris Busch

Bennett, Clarence Frank, Ph.D. (1985) Thesis title: Isolation of a DNA-binding nonhistone protein as glutathione-s-transferase. Advisor: Dr. Lynn Yeoman

Bremer, James W., Ph.D. (1985) Thesis title: Isolation and characterization of two nonhistone proteins from Novikoff hepatoma nuclei and their relationship to actin. Advisor: Dr. Lynn Yeoman

Cantrell, Elroy Taylor, Ph.D. (1972) Thesis title: Induction of Benzpyrene hydroxylase in parenchymal and kupffer cells of rat liver. Advisor: Dr. Edward Bresnick

Cassidy, Brandt G., Ph.D. (1987) Thesis title: In vitro analysis of the cis-acting transcriptional elements of the rat ribosomal gene repeat. Advisor: Dr. Lawrence Rothblum

Catino, Joseph J., Ph.D. (1979) Thesis title: Isolation, characterization and localization of a growth related nonhistone protein. Advisor: Dr. Lynn Yeoman

Chang, Jian, Ph.D. (1995) Thesis title: Covalent DNA alterations induced by Ni(ii) and oxidative stress. Analysis by 32P-postlabeling: Possible mechanism of nickel carcinogenesis. Advisor: Dr. Kurt Randerath

Cheng, Yahua, Ph.D. (2000) Thesis title: Studies on the post-transcriptional 3' end adenylation of small RNAs: mechanism of its formation and possible function(s). Advisor: Dr. Ram Reddy

Crooke, Stanley Thomas, M.D., Ph.D. (1973) Advisor: Dr. Harris Busch

Davis, Joseph R., M.D., Ph.D. (1961) Thesis title: Suppression of amino acid incorporation into chromatographically isolated nuclear proteins by 5-bis-2-chloroethyl-aminouracil. Advisor: Dr. Harris Busch

Desjardins, Raoul, Ph.D. (1966) Thesis title: Large scale isolation of nucleoli for studies on effects of anti-tumor agents on nucleolar DNA synthesis. Advisor: Dr. Harris Busch

Dowd, Frank J. Jr., Ph.D. (1975) Thesis title: Functional characteristics of membrane transport. Advisor: Dr. Arnold Schwartz

Duvernay, Virgil H., Ph.D. (1979) Thesis title: Molecular pharmacological characterization of several anthracycline antitumor antibiotics. Advisor: Dr. Stanley Crooke

Epstein, Paul Norman, Ph.D. (1981) Thesis title: U-snRNAs and U-snRNP particles. Advisor: Dr. Ram Reddy

Finch, Rick A., Ph.D. (1995) Thesis title: Nucleoside and nucleotide modulation of nucleophosmin/B23 localization and rRNA synthesis. Advisor: Dr. Pui-Kwong Chan

Gentry, Deborah, Ph.D. (1995) Advisor: Dr. Addison Taylor

Gokuladas, Mullakkara, Ph.D. (1988) Thesis title: Structural characterization and transcriptional analysis of U6 small nuclear RNA genes. Advisor: Dr. Ram Reddy

Gu, Jian, Ph.D. (1999) Thesis title: Post-transcriptional modification and processing of small RNAs: the 3' end processing of human U6 snRNA and signal recognition particle RNA. Advisor: Dr. Ram Reddy

Hicks, Paul B., Ph.D. (1983) Thesis title: A characterization of the blood-brain barrier in aged rats. Advisor: Dr. Joseph Schoolar

Hill, James Milton, Ph.D. (1971) Thesis title: Messenger activity in various RNA fractions from fetal, neonatal and adult rat liver. Advisor: Dr. Edward Bresnick

Hilliard, Julia K., Ph.D. (1975) Thesis title: Studies of DNA methylation. Advisor: Dr. Thomas Sneider

Hong, Eugene Ph.D. (2008) Thesis title: Characterization of teh U2AF65 Family in Both Transcription and Splicing. Advisor: Dr. Susan Berget

Iskander, Karim Ph.D. (2005) Thesis title: quinone Oxidoreductases in Prevention of Myeloproliferation and Chemical Carcinogenesis. Advisor: Dr. Anil Jaiswal

Jain, Abhinav, Ph.D. (2007) Thesis title: NRF2 Signaling in Oxidative Stress. Advisor: Dr. Anil Jaiswal

Johnson, Carol L, Ph.D. (1971) Thesis title: On the molecular action of local anesthetics. Advisor: Dr. Arnold Schwartz

Jones, Cristopher E., Ph.D. (1979) Thesis title: Nuclear and nucleolar nonhistone protein phosphorylation sites. Advisor: Dr. Mark Olson

Lanclos, Kenneth Daniel, Ph.D. (1972) Thesis title: Induction of microsomal drug metabolizing enzymes by polycyclic hydrocarbons: Transcriptional and translational effects. Advisor: Dr. Edward Bresnick

Li, Donghui, Ph.D. (1988) Investigation of I-compounds (newly discovered indigenous DNA modifications) by different approaches. Advisor: Dr. Kurt Randerath

Lindenmayer, George E., Ph.D. (1970) Thesis title: Biochemical responses of the cardiac cell to various stresses. Advisor: Dr. Arnold Schwartz

Liu, Qing-Rong, Ph.D. (1991) Thesis title: Structure and function studies of nucleophosmin/B23: A putative nucleolar ribosome assembly factor. Advisor: Dr. Pui-Kwong Chan

Long, Delvin J., Ph.D. (2002) Thesis title: Studies on the in vivo roles of quinone oxidoreductases. Advisor: Dr. Anil Jaiswal

Lowe,. David W., M.D., Ph.D. (1990) Thesis title: Regulation of rat ribosomal RNA, U3 small nucleolar RNA and human p120 genes. Advisor: Dr. Ram Reddy

Mamrack, Mark Donovan, Ph.D. (1978) Thesis title: Nucleolar nonhistone protein phosphorylation within highly acidic regions. Advisor: Dr. Mark Olson

Merski, Jerome A., Ph.D. (1978) Thesis title: Ultrastructural studies on the effects of adriamycin in vivo. Advisor: Dr. Yarach Daskal

Mirabelli, Cristopher K., Ph.D. (1981) Thesis title: Studies on the molecular pharmacology of the talisomycins- a group of bleomycin-related anti-tumor antibiotics. Advisor: Dr. Stanley Crooke

Mong, Hsien-Tai (Seymour), Ph.D. (1981) Thesis title: Studies on the molecular pharmacology of cos-platinum and analogs. Advisor: Dr. Stanley Crooke

McGregor, Robert F., Ph.D. (1961) Thesis title: Development of methods of analysis for diethylstilbestrol and application to biochemical studies in stilbestrol treated hamsters. Advisor: Dr. Harris Busch

Parker, David A., Ph.D. (1981) Thesis title: Amplified DNA of the Novikoff hepatoma nucleus. Advisor: Dr. Lawrence Rothblum

Perumal, Karthika, Ph.D. (2001) Thesis title: Studies on the post-transcriptional adenylation at the 3' end of small RNAs. Advisor: Dr. Ram Reddy

Ro-Choi, Tae Suk, M.D., Ph.D. (1968) Thesis title: Effects of Act D on nuclear and nucleolar RNA synthesis. Advisor: Dr. Harris Busch

Schurdak, Mark E., Ph.D. (1987) Thesis title: Partial characterization of the genetic toxicity by the environmental carcinogens in mice. Advisor: Dr. Kurt Randerath

Shappel, Scott Barry, M.D., Ph.D. (1991) Thesis title: Molecular mechanisms of neutrophil activation in myocardial ischemia reflow injury. Advisor: Dr. Addison Taylor

Singh, Ravinder, Ph.D. (1990) Thesis title: A novel cap structure in eukaryotic small nuclear RNAs. Advisor: Dr. Ram Reddy

Smith, Steven Joel, Ph.D. (1969) Thesis title: Subfractions of nuclear RNA: effects of Act D on the RNA of the nuclear envelope. Advisor: Dr. Harris Busch

Starbuck, Wesley C., Ph.D. (1962) Thesis title: Effect of hydroxylethylation on the uptake of rat albumin into tissues of tumor-bearing rats. Advisor: Dr. Harris Busch

Suh, Dick Yung, M.D., Ph.D. (1988) Thesis title: Structural characterization and transcriptional analysis of human U3 small nucleolar RNA genes. Advisor: Dr. Ram Reddy

Tate, Dan Frederick, Ph.D. (1976) Thesis title: Chemical identification of two learning-induced brain peptides. Advisor: Dr. George Ungar

Tseng, Wen-Cheng, Ph.D. (1979) Thesis title: Studies of tRNA modification and ribothymidine synthase activity in tissues of mice treated with 5-fluorouracil. Advisor: Dr. Kurt Randerath

Wang, Wei, Ph.D. (2005) Thesis title: Regulation of Quinone Oxidoreductases. Advisor: Dr. Anil Jaiswal

Wen, Juan, Ph.D. (1991) Thesis title: Antigenic structure of the 86 kDa subunit of the Ku autoantigen. Advisor: Dr. Mariana Yaneva

Wong, Sin-Kuen (Angela) Ph.D. (1984) Thesis title: Studies on the mechanisms of action of the cytotoxic effects of acridinylamino methansulfon-m-anisidide. Advisor: Dr. Stanley Crooke

Wu, Shao-Ping, Ph.D. (1992) Thesis title: The autocrine role of TGF-B's in maintaining cellular quiescence and suppression of tumorigenicity. Advisor: Dr. Michael Brattain

Xiong, Jason, Ph.D. (2000) Thesis title: Ionic Regulation of Epileptiform Activity . Advisor: Dr. Janet Stringer

Yang, Hushan, Ph.D. (2005) Thesis title: Functions of RNA Helicase II/GUalpha Protein in Ribosomal RNa Production. Advisor: Dr. Ben Valdez

Yang-Yen, Hsin-Fang (Angela) Ph.D. (1988) Thesis title: Sequence analysis of the nontranscribed spacer of the rat ribosomal RNA gene and characterization of an HMG-like, DNA binding protein that stimulates rRNA synthesis in vitro. Advisor: Dr. Lawrence Rothblum

Yuan, Yan, Ph.D. (1991) Thesis title: Synthesis of 7-2 small nucleolar RNA. Advisor: Dr. Ram Reddy

Yung, Yat-Ming (Benjamin), Ph.D. (1986) Thesis title: Studies on the translocation and characterization of nucleolar phosphoprotein B23. Advisor: Dr. Pui-Kwong Chan

Zhou, Guo-Hao Karl, Ph.D. (1992) Thesis title: Integrins mediate cell adhesion of colon carcinoma cells and are regulated by EGF and TGF-B. Advisor: Dr. Michael Brattain

Ziober, Barry Lee, Ph.D. (1991) Thesis title: Role of TGF-a in a well differentiated colon carcinoma cell line and a poorly differentiated colon carcinoma cell line. Advisor: Dr. Michael Brattain

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