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Pathology

Houston, Texas

Department of Pathology
Pathology
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Faculty

Perumal Thiagarajan, M.D. Professor

Perumal Thiagarajan

Education

  1. M.B.B.S. (Equivalent to M.D. in US), Tirunelveli Medical College, India, July 1967 - Jan 1974

Internship

  1. Internal Medicine,Long Island College Hospital, July 1974 - June 1975

Residency

  1. Internal Medicine, Veterans Administration and Mount Sinai Hospital, July 1975 - June 1976

Fellowship

  1. Clinical Fellow in Hematology/Oncology Veterans Administration and Mount Sinai Hospital, July 1976 - June 1978

  2. Research Fellow in Hemostasis, Cardeza Foundation for Hematological Research, Jefferson Medical College of Philadelphia, July 1978 - June 1980

Specialty

  1. Hematology

Board Certification

  1. Internal Medicine

  2. Hematology

  3. Pathology (hematology)

Area of Interest

  1. Hemostasis

  2. Thrombosis

Current Position

  1. Professor of Medicine and Pathology, Baylor College of Medicine

  2. Director, Transfusion Medicine and Hematology Laboratory Michael E. DeBakey VA Medical Center

Professional Positions Held

  1. Professor of Medicine and Pathology, Baylor College of Medicine, Sep. 2001 - To present

  2. Professor of Medicine, University of Texas Medical School, July 2000 - Sep. 2001

  3. Associate Professor of Medicine, University of Texas Medical School, Nov. 1993 - 2001

  4. Associate Professor of Medicine, University of Washington, July 1989 - Nov. 1993

  5. Assistant Professor of Medicine, University of Washington, Seattle, May 1986 - June 1989

  6. Assistant Professor of Medicine, Member, Cardeza Foundation, Jefferson Medical College, July 1981 - April 1986

  7. Instructor in Medicine Jefferson Medical College, Philadelphia, July 1980 - June 1981

Honors and Awards

  1. Pfizer Foundation Prize in final year MBBS examination, 1974

  2. E. Merck Gold Medal for Best Outgoing Student in Madurai University, 1974

  3. New Investigator Award from National Institute of Health, 1981-1984

  4. Established Investigator Award from American Heart Association, 1984-1989

  5. Deans Award for excellence in Teaching, University of Texas Houston, 2001

Membership on professional organizations

  1. Member, American Society of Clinical Investigation

  2. Member, American Society for Biochemistry and Molecular Biology

  3. Fellow, American College of Physicians

  4. Member, Royal College of Physicians of United Kingdom

  5. Member, American Federation for Medical Research

  6. Member, American Society of Hematology

  7. Fellow, Council on thrombosis, American Heart Association

  8. Association of American Physicians

Representative Publications

  1. Gushiken FC, Le A,. Arnett FC and Thiagarajan P . Polymorphisms of b 2-glycoprotein I: Phospholipid binding and multimeric structure. Thrombosis Research. 108:175-80, 2003

  2. Borthakur B, Cruz MA, Dong JF, McIntire L, Li F, Lopez J and Thiagarajan P. Sulfatides Inhibit Platelet Adhesion to the von Willebrand Factor A1 Domain under in Flowing Blood Conditions. J of Thrombosis and Hemostasis 1: 1288-95, 2003

  3. Merten, Motamedy S, Ramamurthy S, Arnett, F. C. Thiagarajan P. Sulfatides: Targets for Antiphospholipid Antibodies. Circulation 108:2082-7, 2003

  4. Le A, Dasgupta S, Planque S, Paul S, Thiagarajan P. The Kringle 2 Domain of Prothrombin as the Target for Antiprothrombin Antibodies in Lupus: Characterization from a V Gene Phage Display Library. Biochemistry 43: 4047-54, 2004

  5. Karle S, Planque S, Nishiyama Y, Taguchi H, Zhou YX, Salas M, Lake D, Thiagarajan P , Arnett F, Hanson CV, Paul S. Cross-clade HIV-1 neutralization by an antibody fragment from a lupus phage display library. AIDS . 18(2):329-31, 2004

  6. Guchhait P, López JA , and Thiagarajan P. Characterization of Autoantibodies against Sulfatide from a V-Gene Phage-Display Library Derived from Patients with Systemic Lupus Erythematosus. J immunol Methods 295:129-3, 2004

  7. Conde ID, Nabil F; Tonda R, Thiagarajan P , López, JA, Kleiman NS : Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes. Arteriosclerosis, Thrombosis and Vascular Biology 25:1065-70, 2005

  8. Conde ID, Shrimpton, CN, Thiagarajan P, Lopez JA: Tissue factor-bearing microvesicules arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 106:1604-11, 2005

  9. Dasgupta SK, Thiagarajan P : The role of lactadherin in the phagocytosis of phosphatidylserine-expressing sickle red blood cells by macrophages. Haematologica /The Hematology Journal 90: 1267-68, 2005

  10. Dasgupta SK, Guchhait P, Thiaga raja n P : Lactadherin Binding and Phosphatidylserine Expression on Cell Surface - Comparison with Annexin A5. Translation Research: J Lab Clin Med 148(1):19-25, 2006

  11. Vijayan KV, Liu Y, Souza S, Thiagarajan, P , Bray PF. Fibrinogen and prothrombin binding is enhanced to the Pro33 isoform of purified integrin ?IIb?3 . J of Thrombosis and Hemostasis 4:905-6, 2006

  12. Dasgupta SK, Thiagarajan P. Inhibition of thrombin activity by prothrombin activation fragment 1.2. J Thromb Thrombolysis. ;24(2):157-62. 2007

  13. Conde ID, Bharwani LD, Dietzen DJ;, Pendurthi U, Thiagarajan P, José A. López Microvesicle-Associated Tissue Factor and Trousseau's Syndrome. J of Thrombosis and Hemostasis 70-4, 2007

  14. Guchhait P, Dasgupta SK, Le A, Yellapragada S, López, JA, Thiagarajan P. Lactadherin Mediates Sickle Cell Adhesion to Vascular Endothelial Cells in Flowing Blood. Hematologica /The Hematology Journal 92 : 1266-7, 2007