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Pathology

Houston, Texas

Department of Pathology
Pathology
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Faculty

Stephanie A. Pangas, Ph.D. Assistant Professor

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Education

  • BA Kent State University, Kent OH

  • MS Northwestern University, Evanston IL

  • PhD Northwestern University, Evanston IL

Post-doctoral Training

  • Department of Pathology, Baylor College of Medicine, Houston, TX 2002-2007

Specialty

  • Reproductive Biology

Area of Interest

  • Germ Cell Development

Current Position

  • Assistant Professor, Department of Pathlology, Baylor College of Medicine

Honors and Awards

  • Ruth L. Kirschstein NRSA Postdoctoral Fellowship (NIH) 2004-2007

  • Burroughs Wellcome Career Award in Biomedical Sciences 2006-2010

Membership on professional organizations

  • Society for the Study of Reproduction

  • American Association for the Advancement of Science

Representative Publications

  1. Pangas, S.A ., Li X., Umans, L., Zwijsen, A., Huylebroeck, D., Gutierrez, C., Wang, D., Martin, J.F., Jamin, S.P., Behringer, R.R., Robertson, E.J., and M.M. Matzuk. (2008) Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastic tumor development in mice , Mol. Cell. Biol. , in press
  2. Pangas , S.A . , Jorgez, C., Tran, M., Agno, J., Li, X., Brown, C.J., Kumar, T.R., and M.M. Matzuk (2007). Intraovarian activins are required for female fertility, Mol. Endocrinol . 21:2458-2471
  3. Pangas , S.A . and M.M. Matzuk (2007). The TGF b family in the Reproductive Tract. In: TGF b , 1st Edition ( Cold Spring Harbor Press). R Derynck and K. Miyazono (Eds)
  4. Pangas , S.A. , Li, X., Robertson, E.J., and M.M. Matzuk (2006). Premature luteinization and ovarian failure in ovary-specific Smad4 conditional knockout mice. Mol. Endocrinol . 20:1406-1422
  5. Pangas, S.A. , Choi, Y, Ballow D., Zhao Y., Westphal H., Matzuk, M.M., and A. Rajkovic (2006) Oogenesis requires germ cell specific transcriptional regulators Sohlh1 and Lhx8 , Proc. Natl. Acad. Sci . 103:8090-8095
  6. Pangas, S.A. , Yan, W., Matzuk, M.M., and A. Rajkovic (2004) Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain containing protein. Gene Expression Patterns 5:257-263
  7. McKenzie, L.J., Pangas , S.A. , Carson , S.A. , Kovanci, E., Cisneros, P., Buster, J.E., and M.M. Matzuk (2004). Human granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing in vitro fertilization. Human Reproduction 19:2869-2874
  8. Rajkovic, A., Pangas , S.A. , N., Ballow, D., Suzumori, N., and M.M. Matzuk (2004). NOBOX regulates oocyte-specific gene expression in early folliculogenesis. Science 305: 1157-1159
  9. Pangas , S.A. , Jorgez, C.J., and M.M. Matzuk (2004) Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist, gremlin. J. Biol. Chem. 279: 32281-32286