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Pathology

Houston, Texas

Department of Pathology
Pathology
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Faculty

Xin Ma, M.D., Ph.D. Assistant Professor

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Education

  • M.D., Shandong University, School of Medicine, Jinan, Shandong, China, 1993

  • Ph.D., Department of Medicine, Division of Gastroenterology, Peking Union Medical College (PUMC), Chinese Academy of Medical Sciences, Beijing, China
    Joint degree program training at: Karolinska Institute, Stockholm, Sweden, 2000

Internship

  • Qilu Hospital, School of Medicine, Shandong University, Jinan, 1992-1993

Residency

  • Resident and Chief Resident, Departments of Radiology and Medicine, Peking Union Medical College Hospital (PUMCH), Beijing, China, 1993-1996
    Rotation training at Radiology Department for: X-rays, GI contrast, CT scan, MRI, Ultrasonography, Catheter lab; and Department of Medicine for: Emergency medicine, ICU, CCU, Cardiology, Pulmonary and Critical Care Medicine, Gastroenterology, Oncology/Hematology, Nephrology, Endocrinology, Infectious Disease, Rheumatology

Fellowship

  • Clinical Fellow, Division of Gastroenterology, Department of Medicine, Peking Union Medical College Hospital, Beijing, China, 1996-1998
    Training for endoscope, ERCP, and pancreatic cancer diagnosis

  • Research Fellow, Center for Nutrition and Toxicology, Department of Bioscience at Novum, Karolinska Institute, Sweden, 1998-2000
    Training for molecular epidemiology of Cancer

Specialty

  • Molecular Epidemiology

Board Certification

  • Certifications of Radiology and Medicine by Chinese Ministry of Health, Beijing, China, 1993

Area of Interest

  • Human genetic susceptibility to tuberculosis

  • Molecular epidemiology of Mycobacterium tuberculosis

Current Position

  • Assistant Professor of Department of Pathology, Baylor College of Medicine

Professional Positions Held

  • Assistant Professor, Department of Pathology, Baylor College of Medicine, 2006-Present

  • Postdoctoral Associate and Lab Supervisor, Department of Pathology, Baylor College of Medicine, 2000-2006
    Training for population-based molecular epidemiology on human genetic susceptibility to tuberculosis. FDA Clinical Trials: T-spot (Oxford Immunotech, Inc.); QuantiFERON-TB (Cellestis, Inc.)

  • Scientific Director (volunteer), Katharine Hsu International Research Center of Human Infectious Diseases (KICID), Shandong Provincial Department of Health, China, 2004-Present. Supervising the international collaborative projects (BCM-China) on tuberculosis control, and molecular epidemiology of tuberculosis

Honors and Awards

  • The Award of Excellent Medical Resident, Peking Union Medical College Hospital, 1995

  • Scholarship of Zhou Zi-Zhuan Foundation, Graduate School of PUMC, Chinese Academy of Medical Sciences, 1996

  • Research Fellowship, Karolinska Institute, Sweden, 1997

  • Member of Shandong Council of Tuberculosis Control, 2004

  • Travel Scholarship, Chinese Ministry of Education, 2004

  • Member of Board of Directors, Katharine Hsu Foundation, 2004

  • Founder, Hopson Medical Education and Development System, 2005

  • Featured TV Presentation on Chinese National Education Channel, 2006

Representative Publications

  1. Moran A, Ma X, Graviss E (2006). No Evidence of Association between the +874T/A Single Nucleotide Polymorphism in the First Intron of the Interferon-gamma Gene and Human Susceptibility to Tuberculosis. (in press)
  2. Ma X, Wang H, Deng Y, Liu Z, Pan X, Musser J, Graviss E (2006). RpoB gene Mutations and Molecular Characterization of Rifampin-Resistant Mycobacterium tuberculosis in Shandong Province, China. J Clin Microbiol 44:3409-3412
  3. Qiu L, Teeter L, Liu Z, Ma X, Musser J, and Graviss E (2006), Diagnostic Associations between Pleural and Pulmonary Tuberculosis. J Infect 53:377-386
  4. Porsa E, Cheng L, Seale M, Delclos G, Ma X, Reich R, Musser J, Graviss E (2006). Comparing a new interferon-gamma assay to tuberculin skin test for detection of latent tuberculosis infection in a moderate risk population Clin Vaccine Immunol 13:53-58
  5. Graviss, E, Ma X, Fu Y (2004). Reply to interleukin-8 polymorphism is not associated with pulmonary tuberculosis in The Gambia. J nfect Dis 189:1546
  6. Ma X, Reich R, Wright J, Tooker H, Teeter L, Musser J, Graviss E (2003). No evidence for association between the polymorphism in the 3' untranslated region of interleukin-12B and human susceptibility to tuberculosis. J Infect Dis 188:1116-1118
  7. Ma X, Reich R, Wright J, Tooker H, Teeter L, Musser J, and Graviss E (2003). Association between IL-8 gene and human tuberculosis susceptibility. J Infect Dis 188:349-355
  8. Hemminki K, Jiang Y, Ma X, Yang K, Egevad L, Lindblad P (2002). Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: relation to dietary and other factors. Carcinogenesis 2 23:809-815
  9. Smeds J, Berggren P, Ma X, Xu Z, Hemminki K and Kumar R (2002). Genetic status of cell cycle regulators in squamous cell carcinoma of the esophagus: the CDKN2A (p16INK4a and p14ARF) and p53 genes are major targets for inactivation. Carcinogenesis 23:645-655
  10. Ma X, Wright J, Dou SJ, Olsen P, Teeter L, Adams G, Graviss E (2002). Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility. J Hum Genet 47:140-145
  11. Ma X, Dou S, Wright J, Reich R, Teeter L, El Sahly H, Musser J and Graviss E (2001). 5'Dinucleotide Repeat Polymorphism of NRAMP1 and susceptibility to tuberculosis among caucasian patients in Houston, Texas. Int J Tuberc Lung Dis 6(9):818-823
  12. Ma X, Yang K, Lindblad P, Egevad L, Hemminki K (2001). VHL gene alterations in renal cell carcinoma patients: novel hotspot mutations and linkage disequilibrium. Oncogene 20:5393-5400
  13. Ma X, Jin Q, Forsi A, Hemminki K, and Kummar R (2000). Single nucleotide polymorphism analyses of the human proliferating cell nuclear antigen (PCNA) and FLAP endonuclease (FEN1) genes. Int J Cancer 88:938-942
  14. Chen Z, Ma X, and Yan H (1996). CT evaluation in diagnosis of the pulmonary metastasis of malignant trophoblastic tumors. Chin J Radiol 30:682-685
  15. Chen Z, Ma X, and Yan H. X-ray diagnosis and embryologic basis of the bronchogenic cyst (1995). J Clin Radiol 14:154-157