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Pathology

Houston, Texas

Department of Pathology
Pathology
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Faculty

Yuko Mori-Akiyama, M.D. Assistant Professor

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Education

  1. M.D., Kyoto Prefectural University of Medicine, Kyoto, Japan

Post-doctoral Training

  1. The University of Texas, M. D. Anderson Cancer Center, Department of Molecular Genetics

Area of Interest

  1. Cell fate

  2. Cell differentiation

  3. Intestinal epithelial cell biology

Current Position

  1. Assistant Professor of Pathology

Professional Positions Held

  1. Assistant Professor of Genetics, The University of Texas, M.D. Anderson Cancer Center

Honors and Awards

  1. AACR-AstraZeneca Scholar in Award, American Association for Cancer Research, 2006

  2. Keystone Symposia Scholarship Award 2006, Keystone Symposia, 2006

  3. FASEB summer research conferences GI tract, travel award, 2006

  4. The Texas Digestive Disease Center Pilot / Feasibility Award, 2008

  5. Sara-Jordan Research Scholar Award, American Gastroenterological Association, 2008

Membership on professional organizations

  1. American Gastroenterology Association, member, 2006 - present

  2. Texas Digestive Disease Center , associate member, 2006 - present

Representative Publications

  1. Mori-Akiyama, Y. , van den Born, M. van Es, J. H., Hamilton, S. R., Adams, H. P., Zhang, J., Clevers, H., de Crombrugghe, B. SOX9 is required for the differentiation of Paneth cells in the intestinal epithelium. Gastroenterology, 2007.

  2. Akiyama, H., Kamitani, T., Yang, X., Kandyil, R., Bridgewater , L. C., Fellous, M., Mori-Akiyama, Y., and de Crombrugghe, B. The transcriptional factor Sox9 is degraded by the ubiquitin-proteasome system and stabilized by a mutation in a ubiquitin-target site. Matrix Biol. 23:499-505, 2005.

  3. Akiyama, H., Lyons, J. P, Mori-Akiyama, Y. , Yang, X., Zhang, R., Zhang, Z, Deng, J. M., Taketo M. M., Nakamura, T., Behringer, R. R., McCrea, P. D., de Crombrugghe, B. Interactiuon between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 18:1072-1087, 2004.

  4. Mori-Akiyama, Y ., Akiyama, H., Rowitch, D. H., de Crombrugghe, B. Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Proc. Natl. Acad. Sci. USA, 100:9360-9365, 2003.