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Pathology

Houston, Texas

Department of Pathology
Pathology
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Faculty

Adekunle M. Adesina, M.D., Ph.D. Associate Professor of Pathology

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Education

  • M.B., B.S. (MD equivalent) 1980 – University of Ibadan, Ibadan, Nigeria

  • M.Sc. 1985 – University of Ibadan, Ibadan, Nigeria

  • Ph.D. 1997 – McGill University, Montreal, Quebec, Canada

Internship

  • Rotational Internship - University College Hospital, Ibadan, Nigeria, 1980 – 1981

Residency

  • Anatomic Pathology - University College Hospital, Ibadan, Nigeria, 1982 – 1986

Fellowship

  • Anatomic Pathology and Neuropathology – Medical Center Hospital and The University of Vermont, Burlington, VT, 1986 – 1990

  • Surgical Pathology, Cytopathology and Molecular Pathology, Fox Chase Cancer Center, Philadelphia, PA, 1992 – 1994

Post-doctoral Training

  • Molecular Genetics – Ludwig Institute for Cancer Research and Montreal Neurological Institute, Montreal, Quebec, Canada, 1990 – 1992

Specialty

  • Anatomic Pathology

  • Neuropathology

  • Molecular Pathology

Board Certification

  • Anatomic Pathology and Neuropathology, 1990

  • Molecular Genetic Pathology, 2001

Area of Interest

  • Molecular Neuro-oncology

  • Neuromuscular disease – histologic diagnosis and applications of molecular methods in diagnosis

Current Position

  • Associate Professor of Pathology

  • Chief of Neuropathology Program

  • Director of Neuropathology Fellowship Training Program

  • Director of Molecular Neuropathology Laboratory

Professional Positions Held

  • Associate Professor of Pathology and Director of Neuropathology, Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2001 – 2002

  • Assistant Professor of Pathology Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 1994 – 2001

Honors and Awards

  • Honorable mention Neil Award for the best paper in Experimental Neuropathology by the American Association of Neuropathologists at the International Congress of Neuropathology, San Francisco, September 10 – 16, 2006

  • Unsung Hero award – Given by the Department of Pathology in appreciation of dedication and support of the Department of Pathology teaching programs, 2001

  • Richard W Leech Teaching Award – presented by the Department of Pathology house staff to the faculty member who has best exemplified excellence in teaching, 2001

  • Medical Research Council of Canada Postdoctoral Research Fellowship Award, 1992

  • Departmental prize for best student in Hematology, 1979

  • George Edington prize for best student in Pathology, 1979

  • Distinction in Pathology, College of Medicine, University of Ibadan, 1977

  • Full Medical Education Federal Government Scholarship award, 1975

Membership on professional organizations

  • Member, United States and Canadian Academy of Pathology, 2004

  • Inspector, Anatomic Pathology and Molecular Pathology, College of American Pathologists, 1997 – present

  • Member, Association for Molecular Pathology, 1995 – present

  • Member, American Association for the Advancement of Science, 1995 – present

  • Member, Oklahoma State Association for Pathologists, 1994 – 2002

  • Member, American Association of Neuropathologists, 1991 – present

  • Member, College of American Pathologists, 1991 – present

Representative Publications

  1. Wong, KK, Tsang, YTM, Chang, Y-M, Su, J, Di Francesco, AM, Meco, D, Riccardi, R, Perlaky, L, Dauser, RC, Adesina, A, Bhattacharjee, M, Chintagumpala, M, Lau, C: Genome-wide Allelic Imbalance Analysis of Pediatric Gliomas by Single Nucleotide Polymorphic Allele (SNP) Array Cancer Res, 2006; 66 (23): 11172

  2. Maryam Fouladi, Susan M. Blaney, Tina Young Poussaint, Burgess B. Freeman III, Roger McLendon, Christine Fuller, Adekunle M. Adesina, Michael L. Hancock, Joanna S. Remack, Mary K. Danks, Clinton Stewart, Percy Ivy, James M. Boyett, Larry E. Kun, Amar Gajjar: A Phase II Study of Oxaliplatin in Children with Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumors and Atypical Teratoid Rhabdoid Tumors: A Pediatric Brain Tumor Consortium Study. Cancer. 2006 Oct 3; [Epub ahead of print]

  3. Qin Shu, Bobbie Antalffy, Adekunle Adesina, Jack Su, Ching-Nan Ou, Torsten Pietsch, Susan Blaney, Ching C. Lau, Xiao-Nan Li.: Valproic Acid Prolongs Survival Times of SCID Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts. Clin Cancer Res 2006 Aug 1;12(15):4687-94.

  4. Massimiliano De Bortoli, Robert C. Castellino, Xin-Yan Lu, Jeffrey Deyo, Lisa Marie Sturla, Adekunle M Adesina, Laszlo Perlaky, Scott L. Pomeroy, Ching C. Lau, Tsz-Kwong Man, Pulivarthi H. Rao, John Y.H. Kim: Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. BMC Cancer 2006, 6:223

  5. Xiao-Nan Li, Qin Shu, Jack M. Su, Adekunle M. Adesina, Kwong Kwok Wong, Laszlo Perlaky, Barbara A. Antalffy, Susan Blaney, Ching C. Lau: Differential Expression of Survivin Splice Isoforms in Medulloblastomas. Neuropath Applied Neurobiol In Press

  6. Margaret C Thompson, Christine Fuller, Twala L Hogg, James Dalton, David Finkelstein, Ching C Lau, Murali Chingtagumpala, Adekunle Adesina, David M Ashley, Stewart J Kellie, Michael D Taylor, Tom Curran, Amar Gajjar, and Richard J Gilbertson: Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol. 2006 Apr 20;24(12):1924-31. Epub 2006 Mar 27

  7. Adesina AM: Intraoperative consultation in the diagnosis of pediatric brain tumors. Arch Pathol Lab Med 2005,129 (12):1653 –1660

  8. Wong K-K, Chang Y-M, Tsang YTM, Perlacky L, Su J, Adesina A, Armstrong DL, Bhattacharjee M, Dauser R, Blaney S, Chintagumpala M, Lau CC: Expression analysis of juvenile pilocytic astrocytoma by oligonucleotide microarray reveals two potential subgroups. Cancer Res, 2005, 65:76-84

  9. Adesina AM, Dunn ST, Nalbantoglu J: Expression of p27kip1 and p53 gene in medulloblastoma; relationship with cell proliferation and survival. Path Res & Pract 2000; 196:243-250.

  10. Adesina AM, Dooley N, Nalbantoglu J, Yong VW: Differential role of protein kinase C mediated signaling in the proliferation of medulloblastoma cell lines. Int J Oncol 1998; 12:759-768.

  11. Adesina AM, Nalbantoglu J, Cavenee WK: p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 1994; 54:5649-5651

  12. Verma A, Bradley WG, Adesina AM, Sofferman R, Pendlebury WW: Inclusion body myositis with cricopharyngeus muscle involvement and severe dysphagia. Muscle & Nerve 1991; 14:470-473.

  13. Tandan R, Taylor R, Adesina A, Sharma K, Fries T, Pendlebury : Benign autosomal syndrome of neuronal Charcot-Marie tooth disease, ptosis, parkinsonism and dementia. Neurology 1990; 40:773-779.