Tom Cooper Laboratory
The recent realization that most human genes generate multiple protein isoforms via alternative splicing has revealed an extensive degree of regulation that remains to be explored.
The Tom Cooper Lab is interested in understanding the mechanisms of this regulation, from how RNA binding proteins regulate splicing of individual pre-mRNAs to the signaling events that coordinate splicing networks during development.
We also study myotonic dystrophy, the most common form of adult onset muscular dystrophy, in which disrupted splicing regulation causes the primary features of the disease.
Tom Cooper, M.D.
S. Donald Greenberg Professor of Pathology
Office Phone: 713-798-3141
Lab Phone: 713-798-5021
Fax: 713-798-5838