|
Selected
Publications:
Rajagopalan L, Pereira FA, Lichtarge O, Brownell WE. Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis. Methods Mol Biol 2009;493:287-97.
Sfondouris J, Rajagopalan L, Pereira FA, Brownell WE. Membrane composition modulates prestin-associated charge movement. J Biol Chem 2008;283:22473-81.
Anvari B, Zhang R, Qian F, Rajagopalan L, Pereira FA, Brownell WE. Effects of prestin on membrane mechanics and electromechanics. Conf Proc IEEE Eng Med Biol Soc 2007;2007:5384-6.
Brownell WE. Poking versus deflection: anistrophy in action. Biophys J 2008;94:415708.
Schumacher RK, Popel As, Anvari B, Brownell WE, Spector AA. Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane. J Biomech Eng 2008;13):031007.
Rajagopalan L, Greeson JN, Xia A, Liu H, Sturm A, Raphael RM, Davidson AL, Oghalai JS, Pereira FA, Brownell WE. Tuning of the outer hair cell motor by membrane cholesterol. J Biol Chem 2007;282:36659-70.
Zhang R, Qian F, Rajagopalan L, Pereira FA, Brownell WE, Anvari B. Prestin modulates mechanics and electromechanical force of the plasma membrane. Biophys J 2007;93:L07-9.
Liao Z, Feng S, Popel AS, Brownell WE, Spector AA. Outer hair cell active force generation in the cochlear environment. J Acoust Soc Am 2007;122:2215-25.
Zhi M, Ratnanather JT, Ceyhan E, Popel AS, Brownell WE. Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hear Res 2007;228:95-104.
Sturm AK, Rajagopalan L, Yoo D, Brownell WE, Pereira FA. Functional expression and microdomain localization of prestin in cultured cells. Otolaryngol Head Neck Surg 2007;136:434-9.
Ermilov SA, Murdock DR, Qian F, Brownell WE, Anvari B. Studies of plasma membrance mechanics and plasma membrane-cytoskeleton interactions using optical tweezers and fluorescence imaging. J Biomech 2007;40:476-80.
Farrell B, Shope CD, Brownell WE. Voltage dependent capacitance of human embryonic kidney (HEK) cells. Phys Rev E Stat Nonlin Soft Matter Phys 2006;73:041930.
Evans MB, Tonini R, Shope CD, Oghalai JS, Jerger JF, INsull W Jr, Brownell WE. Dyslipidemia and auditory function. Otol Neurotol 2007;27:609-14.
de Monvel JB, Brownell WE, Ulfendahl M. Lateral diffusion anisotrophy and membrane lipid/skeleton interaction in outer hair cells. Biophysical J 2006;91:364-81.
Nakagawa T, Oghalai JS, Saggau P, Rabbitt RD, Brownell WE. Photometric recording of transmembrane potential in outer hair cells. J Neural Eng 2006;3:79-86.
Rajagopalan L, Patel N, Madabushi S, Goddard JA, Anjan V, Lin F, Shope C, Farrell B, Lichtarge O, Davidson AL, Brownell WE, Pereira FA. Essential helix interactions in the anion transporter domain of prestin revealed by evolutionary trace analysis. J Neurosci 2006;26:12727-34.
Bliko O, Reddy GD, Anvari B, Brownell WE, Saggau P. Standing wave total internal reflection fluorescence microscopy to measure the size of nanostructures in living cells. J Biol Optics 200611:;064013.
Liao Z, Popel AS, Brownell WE, Spector AA. Effect of voltage-dependent membrance properties on active force generation in cochlear outer hair cell. J Acoust Soci Am 2005;118:3737-46.
Liao Z, Popel AS, Brownell WE, Spector AA. High-frequency force generation in the constrained cochlear outer hair cell: a model study. J Assoc Res Otolaryngol 2005;6:378-89.
Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B. Effects of chlorpromazine on mechanical properties of the outer hair cell plasma mambrane. Biophys J 2005;89:4090-5.
Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Ann Biomed Eng 2005;33:991-1002.
Ermilov SA, Murdock DR, El-Daye D, Brownell WE, Anvari B. Effects of salicylate on plasma membrance mechanics. J Neurophysiol 2005;94:2105-10.
Liao Z, Popel AS, Brownell WE, Spector AA. Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment. J Acoust Soc Am 2005;117:2147-57.
Rabbitt RD, Ayliffe HE, Christensen D, Pamarthy K, Durney C, Clifford S, Brownell WE. Evidence of piezoelectric resonance in isolated outer hair cells. Biophys J 2005;88:2257-65.
Weizel EK, Tasker R, Brownell WE. Outer hair cell piezoelectricity: frequency response enhancement and resonance behavior. J Acoust Soc Am 2003;114:1462-6.
Spector AA, Brownell WE, Popel AS. Effect of outer hair cell piezoelectricity on high-frequency receptor potentials. J Acoust Soc Am 2003;113:453-61.
Wang X, Su H, Copenhagen LD, Vaishnav S, Pieri F, Shope CD, Brownell WE, De Biasi M, Paylor R, Bradley A. Urocortin-deficient mice display normal stress-induced anxiety behavior at autonomic control but an impaired acoustic startle response. Mol Cell Biol 2002;22:6605-10.
Brownell WE. On the origins of outer hair cell electromotility. In Berlin CI, Hood LJ, Ricci AJ, eds. Hair cell micromechanics and otoacoustic emissions. Albany, NY: Delmar-Thomson Learning; 2002. pp. 25-47.
Li Z, Anvari B, Takashima M, Brecht P, Torres JH, Brownell WE. Membrane tether formation from outer hair cells with optical tweezers. Biophys J 2002;82:1386-95.
Morimoto N, Raphael RM, Nygren A, Brownell WE. Excess plasma membrance and effects of ionic amphipaths on the mechanics of the outer hair cell lateral wall. Am J Physiol Cell Physiol 2002;282: C1076-1086.
Brownell WE, Spector AA, Raphael RM, Popel AS. Micro- and nanomechanics of the cochlear outer hair cell. Ann Rev Biomed Eng 299103:169-94.
Lue AJ-C, Zhao H-B, Brownell WE. Chlorpromazine alters outer hair cell electromotility. Otolaryngol Head Neck Surg 2001;125:71-6.
Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Harvesting human hair cells. Ann Otol Rhinol Laryngol 2000;109:9-16.
Oghalai JS, Zhao H-B, Kutz JW, Brownell WE. Voltage- and tension-dependent lipid mobility in the outer hair cell plasma membrane. Science 2000;287:658-61.
Raphael RM, Popel AS, Brownell WE. A membrane bending model of outer hair cell electromotility. Biophys J 2000;78:2844-52.
Ratnanather JT, Popel AS, Brownell WE. An analysis of the hydraulic conductivity of the extracisternal space of the cochlear outer hair cell. J Math Biol 2000;40:372-82.
Brownell WE. How the Ear Works - Nature's Solutions For Listening. Volta Review 1999;99:9-28.
Lue AJ, Brownell WE. Salicylate induced changes in outer hair cell lateral wall stiffness. Hear Res 1999;135:163-8.
Oghalai JS, Tran TD, Raphael RM, Nakagawa T, Brownell WE. Transverse and lateral mobility in outer hair cell lateral wall membranes. Hear Res 1999;135:19-28.
Spector AA, Brownell WE, Popel AS. Nonlinear active force generation by cochlear outer hair cell. J Acoust Soc Am 1999;105:2414-20.
Brownell WE, Popel AS. Electrical and mechanical anatomy of the outer hair cell. In: Palmer AR, Rees A, Summerfield AQ, Meddis R, eds. Psychophysical and Physiological Advances in Hearing. London: Whurr Publishers; 1998. pp. 89-96.
Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Ionic currents and electromotility in human hair cells. J Neurophysiol 1998;79:2235-9.
Oghalai JS, Patel AA, Nakagawa T, Brownell WE. Fluorescence-imaged microdeformation of the outer hair cell lateral wall. J Neurosci 1998;18:48-58.
Halter JA, Kruger RP, Yium MJ, Brownell WE. The influence of the subsurface cisterna on the electrical properties of the outer hair cell. Neuroreport 1997;8:2517-21.
Sit PS, Lue A, Spector AA, Popel AS, Brownell WE. Micropipet aspiration on the outer hair cell lateral wall. Biophys J 1997; 72:2812-9.
Chertoff ME, Brownell WE. Characterization of cochlear outer hair cell turgor. Am J Physiol 1994;266:C467--C479.
Dieler R, Shehata-Dieler WE, Brownell WE. Concomitant salicylate-induced alterations of outer hair cell subsurface cisternae and electromotility. J Neurocytol 1991;20:637653.
Brownell WE. Outer hair cell electromotility and otoacoustic emissions. Ear Hear 1990;11:82-92.
Zidanic M, Brownell WE. The fine structure of the intracochlear potential field. I. The silent current. Biophys J 1990;57:1253-68.
Siegel JH, Brownell WE. Synaptic and golgi membrane recycling in cochlear hair cells. J Neurocytol 1986;15:311-28.
Brownell WE, Bader CR, Bertrand D, de Ribaupierre Y. Evoked mechanical responses of isolated cochlear outer hair cells. Science 1985;227:194-6.
Brownell WE, Manis PB, Zidanic M, Spirou GA. Acoustically evoked radial current densities in scala tympani. J Acoust Soc Am 1983;74:792-800.
Brownell WE. Cochlear transduction: An integrative model and review. Hear Res 1982;6:335-60.
Young ED, Brownell WE. Responses to tones and noise of single cells in dorsal cochlear nucleus of unanesthetized cats. J Neurophysiol 1976;39:282-300.
Brownell WE. Organization of the cat trapezoid body and the discharge characteristics of its fibers. Brain Res 1975; 94:413-33.
Return to Physician Directory | Otolaryngology Home page
BCM Public | BCM Intranet | Privacy Notices | Contact BCM | BCM Site Map |
©2001-2008 Baylor College of Medicine
Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery
Mail: One Baylor Plaza, NA102, Houston, TX 77030
Phone: 713-798-5906
E-mail: oto@bcm.edu
Last modified:Dec. 01, 2008
|
