Publications by ADMDC Members

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• Benge JF, Balsis S, Geraci L, Massman PJ, Doody RS. How Well Do the ADAS-cog and its Subscales Measure Cognitive Dysfunction in Alzheimer's Disease? Dement Geriatr Cogn Disord. 2009;28:63-69.
• Doody RS, Ferris SH, Salloway S, Sun Y, Goldman R, Watkins WE, Xu Y, Murthy AK. Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial. Neurology. 2009;72:1555-61.
• Doody RS. Commentary on "a roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Centers of excellence in Alzheimer's disease: it is time to better integrate patient care and clinical research to improve the prevention and treatment of Alzheimer's disease. Alzheimers Dement. 2009;5:133-6.
• Khachaturian ZS, Snyder PJ, Doody R, Aisen P, Comer M, Dwyer J, Frank RA, Holzapfel A, Khachaturian AS, Korczyn AD, Roses A, Simpkins JW, Schneider LS, Albert MS, Egge R, Deves A, Ferris S, Greenberg BD, Johnson C, Kukull WA, et al. A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement. 2009;5:85-92.
• Na HR, Lee SH, Lee JS, Doody RS, Kim SY. Korean Version of the Baylor Profound Mental Status Examination: A Brief Staging Measure for Patients with Severe Alzheimer's Disease. Dement Geriatr Cogn Disord. 2009;27:69-75.
• Snyder PJ, Papp KV, Bartkowiak J, Jackson CE, Doody RS. Commentary on "a roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Recruitment of participants for Alzheimer's disease clinical trials: the role of trust in caregivers, clinical researchers, regulatory authorities, and industry sponsors. Alzheimers Dement. 2009;5:122-4.

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• Doody RS, Corey-Bloom J, Zhang R, Li H, Ieni J, Schindler R. Safety and tolerability of donepezil at doses up to 20 mg/day: results from a pilot study in patients with Alzheimer's disease. Drugs Aging. 2008;25:163-74.
• Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, Seely L, Hung D. Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study. Lancet. 2008;372:207-15.
• Doody RS, Tariot PN, Pfeiffer E, Olin JT, Graham SM. Meta-analysis of six-month memantine trials in Alzheimer’s disease. Alzheimers Dement. 2008;3:7-17.
• Doody RS. Cholinesterase inhibitors and memantine: Best practices. CNS Spectr. 2008;13:34-5.
• Doody RS. We should not distinguish between symptomatic and disease-modifying treatments in Alzheimer's disease drug development. Alzheimers Dement. 2008;4:S21-5.
• Jack CR, Jr., Petersen RC, Grundman M, Jin S, Gamst A, Ward CP, Sencakova D, Doody RS, Thal LJ. Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI. Neurobiol Aging. 2008;29:1285-95.
• Jones RW, Kivipelto M, Feldman H, Sparks L, Doody R, Waters DD, Hey-Hadavi J, Breazna A, Schindler RJ, Ramos H. The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics. Alzheimers Dement. 2008;4:145-53.
• Kelly PA, Dyer CB, Pavlik V, Doody R, Jogerst G. Exploring self-neglect in older adults: preliminary findings of the self-neglect severity scale and next steps. J Am Geriatr Soc. 2008;56 Suppl 2:S253-60.
• O'Bryant SE, Waring SC, Cullum CM, Hall J, Lacritz L, Massman PJ, Lupo PJ, Reisch JS, Doody R. Staging dementia using Clinical Dementia Rating Scale Sum of Boxes scores: a Texas Alzheimer's research consortium study. Arch Neurol. 2008;65:1091-5.
• Sitburana O, Rountree S, Ondo WG. Weight change in Parkinson and Alzheimer patients taking atypical antipsychotic drugs. J Neurol Sci. 2008;272:77-82.
• Yan JH, Rountree S, Massman P, Doody RS, Li H. Alzheimer's disease and mild cognitive impairment deteriorate fine movement control. J Psychiatr Res. 2008;42:1203-12.

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• Atchison TB, Massman PJ, Doody RS. Baseline cognitive function predicts rate of decline in basic-care abilities of individuals with dementia of the Alzheimer's type. Arch Clin Neuropsychol. 2007;22:99-107.
• Black SE, Doody R, Li H, McRae T, Jambor KM, Xu Y, Sun Y, Perdomo CA, Richardson S. Donepezil preserves cognition and global function in patients with severe Alzheimer disease. Neurology. 2007;69:459-69.
• Cummings JL, Doody R, Clark C. Disease-modifying therapies for Alzheimer disease: challenges to early intervention. Neurology. 2007;69:1622-34.
• Park KW, Pavlik VN, Rountree SD, Darby EJ, Doody RS. Is functional decline necessary for a diagnosis of Alzheimer's disease? Dement Geriatr Cogn Disord. 2007;24:375-9.
• Rountree SD, Waring SC, Chan WC, Lupo PJ, Darby EJ, Doody RS. Importance of subtle amnestic and nonamnestic deficits in mild cognitive impairment: prognosis and conversion to dementia. Dement Geriatr Cogn Disord. 2007;24:476-82.

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• Dyer CB, Kelly PA, Pavlik VN, Lee J, Doody RS, Regev T, Pickens S, Burnett J, Smith SM. The making of a self-neglect severity scale. J Elder Abuse Negl. 2006;18:13-23.
• Fillit HM, Doody RS, Binaso K, Crooks GM, Ferris SH, Farlow MR, Leifer B, Mills C, Minkoff N, Orland B, Reichman WE, Salloway S. Recommendations for best practices in the treatment of Alzheimer's disease in managed care. Am J Geriatr Pharmacother. 2006;4 Suppl A:S9-S24; quiz S25-S28.
• Geldmacher DS, Frolich L, Doody RS, Erkinjuntti T, Vellas B, Jones RW, Banerjee S, Lin P, Sano M. Realistic expectations for treatment success in Alzheimer's disease. J Nutr Health Aging. 2006;10:417-29.
• Pavlik VN, Doody RS, Massman PJ, Chan W. Influence of premorbid IQ and education on progression of Alzheimer's disease. Dement Geriatr Cogn Disord. 2006;22:367-77.
• Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ. A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease. Arch Neurol. 2006;63:49-54.
• Schneider LS, Clark CM, Doody R, Ferris SH, Morris JC, Raman R, Reisberg B, Schmitt FA. ADCS Prevention Instrument Project: ADCS-clinicians' global impression of change scales (ADCS-CGIC), self-rated and study partner-rated versions. Alzheimer Dis Assoc Disord. 2006;20:S124-38.

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• Doody R, Pavlik V, Massman P, Kenan M, Yeh S, Powell S, Cooke N, Dyer C, Demirovic J, Waring S, Chan W. Changing patient characteristics and survival experience in an Alzheimer's center patient cohort. Dement Geriatr Cogn Disord. 2005;20:198-208.
• Doody RS. Refining treatment guidelines in Alzheimer's disease. Geriatrics. 2005;Suppl:14-20.
• Graham DP, Kunik ME, Doody R, Snow AL. Self-reported awareness of performance in dementia. Brain Res Cogn Brain Res. 2005;25:144-52.
• Hoyt BD, Massman PJ, Schatschneider C, Cooke N, Doody RS. Individual growth curve analysis of APOE epsilon 4-associated cognitive decline in Alzheimer disease. Arch Neurol. 2005;62:454-9.
• Pavlik VN, Hyman DJ, Doody R. Cardiovascular risk factors and cognitive function in adults 30-59 years of age (NHANES III). Neuroepidemiology. 2005;24:42-50.
• Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352:2379-88.
• Roman GC, Wilkinson DG, Doody RS, Black SE, Salloway SP, Schindler RJ. Donepezil in vascular dementia: combined analysis of two large-scale clinical trials. Dement Geriatr Cogn Disord. 2005;20:338-44.
• Snow AL, Graham DP, Molinari VA, Orengo CA, Doody RS, Norris MP, Kunik ME. Factors affecting deficit awareness in persons with dementia. Dement Geriatr Cogn Disord. 2005;20:133-9.
• Snow AL, Kunik ME, Molinari VA, Orengo CA, Doody R, Graham DP, Norris MP. Accuracy of self-reported depression in persons with dementia. J Am Geriatr Soc. 2005;53:389-96.
• Waring SC, Doody RS, Pavlik VN, Massman PJ, Chan W. Survival among patients with dementia from a large multi-ethnic population. Alzheimer Dis Assoc Disord. 2005;19:178-83.

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• Doody R, Wirth Y, Schmitt F, Mobius HJ. Specific functional effects of memantine treatment in patients with moderate to severe Alzheimer's disease. Dement Geriatr Cogn Disord. 2004;18:227-32.
• Doody RS, Dunn JK, Huang E, Azher S, Kataki M. A method for estimating duration of illness in Alzheimer's disease. Dement Geriatr Cogn Disord. 2004;17:1-4.
• Graham DP, Cully JA, Snow AL, Massman P, Doody R. The Alzheimer's Disease Assessment Scale-Cognitive subscale: normative data for older adult controls. Alzheimer Dis Assoc Disord. 2004;18:236-40.
• Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR, Jr., Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, et al. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol. 2004;61:59-66.
• Snow AL, Norris MP, Doody R, Molinari VA, Orengo CA, Kunik ME. Dementia Deficits Scale. Rating self-awareness of deficits. Alzheimer Dis Assoc Disord. 2004;18:22-31.

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• Clark CM, Xie S, Chittams J, Ewbank D, Peskind E, Galasko D, Morris JC, McKeel DW, Jr., Farlow M, Weitlauf SL, Quinn J, Kaye J, Knopman D, Arai H, Doody RS, DeCarli C, Leight S, Lee VM, Trojanowski JQ. Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol. 2003;60:1696-702.
• Davis RN, Massman PJ, Doody RS. Effects of blood pressure on neuropsychological functioning in Alzheimer's disease. Arch Clin Neuropsychol. 2003;18:19-32.
• Davis RN, Massman PJ, Doody RS. WAIS-R factor structure in Alzheimer's disease patients: a comparison of alternative models and an assessment of their generalizability. Psychol Aging. 2003;18:836-43.
• Doody RS. Current treatments for Alzheimer's disease: cholinesterase inhibitors. J Clin Psychiatry. 2003;64 Suppl 9:11-7.
• Doody RS. Update on Alzheimer drugs (donepezil). Neurologist. 2003;9:225-9.
• Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ. Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med. 2003;348:1333-41.
• Smith RG, Roher AE, Appel SH, Doody RS, Killian JM, Corey-Bloom J, Sabbagh MN. Autonomic sudomotor dysfunction in Alzheimer's disease. Curr Med Chem – Imun Endoc Metab Agents. 2003;3:77-84.
• Wilkinson D, Doody R, Helme R, Taubman K, Mintzer J, Kertesz A, Pratt RD. Donepezil in vascular dementia: a randomized, placebo-controlled study. Neurology. 2003;61:479-86.

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• Quinn J, Moore M, Benson DF, Clark CM, Doody R, Jagust W, Knopman D, Kaye JA. A videotaped CIBIC for dementia patients: validity and reliability in a simulated clinical trial. Neurology. 2002;58:433-7.
• Weiner MF, Doody RS, Sairam R, Foster B, Liao TY. Prevalence and incidence of major depressive disorder in Alzheimer's disease: findings from two databases. Dement Geriatr Cogn Disord. 2002;13:8-12.

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• Davis RN, Massman PJ, Doody RS. Cognitive intervention in Alzheimer disease: a randomized placebo-controlled study. Alzheimer Dis Assoc Disord. 2001;15:1-9.
• Doody RS, Dunn JK, Clark CM, Farlow M, Foster NL, Liao T, Gonzales N, Lai E, Massman P. Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001;12:295-300.
• Doody RS, Geldmacher DS, Gordon B, Perdomo CA, Pratt RD. Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol. 2001;58:427-33.
• Doody RS, Massman P, Dunn JK. A method for estimating progression rates in Alzheimer disease. Arch Neurol. 2001;58:449-54.
• Doody RS, Stevens JC, Beck C, Dubinsky RM, Kaye JA, Gwyther L, Mohs RC, Thal LJ, Whitehouse PJ, DeKosky ST, Cummings JL. Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56:1154-66.
• Mohs RC, Doody RS, Morris JC, Ieni JR, Rogers SL, Perdomo CA, Pratt RD. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology. 2001;57:481-8.
• Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B. Current concepts in mild cognitive impairment. Arch Neurol. 2001;58:1985-92.
• Tangalos E, Doody R, Tariot P. Alzheimer's disease in long-term care: maximizing treatment options. J Am Med Dir Assoc. 2001;2:H17-20.
• Doody RS, Azher SN, Haykal HA, Dunn JK, Liao T, Schneider L. Does APO epsilon4 correlate with MRI changes in Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2000;69:668-71.
• Doody RS. Mortality from pneumonia and hip fractures in patients with advanced dementia. Jama. 2000;284:2447; author reply 2448.
• Doody RS. The issue of representation in brain research. Brain Cogn. 2000;42:26-8.
• Hanna PA, Doody RS. Alien limb sign. Adv Neurol. 2000;82:135-45.
• Mulnard RA, Cotman CW, Kawas C, van Dyck CH, Sano M, Doody R, Koss E, Pfeiffer E, Jin S, Gamst A, Grundman M, Thomas R, Thal LJ. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. Jama. 2000;283:1007-15.
• Rogers SL, Doody RS, Pratt RD, Ieni JR. Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of a US multicentre open-label study. Eur Neuropsychopharmacol. 2000;10:195-203.
• Doody RS, Strehlow SL, Massman PJ, Feher EP, Clark C, Roy JR. Baylor profound mental status examination: a brief staging measure for profoundly demented Alzheimer disease patients. Alzheimer Dis Assoc Disord. 1999;13:53-9.
• Doody RS, Vacca JL, Massman PJ, Liao TY. The influence of handedness on the clinical presentation and neuropsychology of Alzheimer disease. Arch Neurol. 1999;56:1133-7.
• Doody RS. Clinical benefits of a new piperidine-class AChE inhibitor. Eur Neuropsychopharmacol. 1999;9 Suppl 2:S69-77.
• Doody RS. Clinical profile of donepezil in the treatment of Alzheimer's disease. Gerontology. 1999;45 Suppl 1:23-32.
• Doody RS. Therapeutic standards in Alzheimer disease. Alzheimer Dis Assoc Disord. 1999;13 Suppl 2:S20-6.
• Doody R, Whitehouse PJ, Chen Q, Wang L, Wu Q, Rosser M, Xu XH. Alzheimer disease-related activities in China: a report from the International Working Group on the Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1998;12:263-5.
• Doody RS, Massman PJ, Mawad M, Nance M. Cognitive consequences of subcortical magnetic resonance imaging changes in Alzheimer's disease: comparison to small vessel ischemic vascular dementia. Neuropsychiatry Neuropsychol Behav Neurol. 1998;11:191-9.
• Rogers SL, Doody RS, Mohs RC, Friedhoff LT. Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group. Arch Intern Med. 1998;158:1021-31.
• Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Neurology. 1998;50:136-45.
• Amaducci L, Baldereschi M, Doody R, Chandra V, Gaines AD. Cultural issues in the clinical diagnosis of Alzheimer disease. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:19-21.
• Antuono P, Doody R, Gilman S, Huff J, Scheltens P, Ueda K, Khachaturian ZS. Diagnostic criteria for dementia in clinical trials. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:22-5.
• Clark CM, Ewbank D, Lerner A, Doody R, Henderson VW, Panisset M, Morris JC, Fillenbaum GG, Heyman A. The relationship between extrapyramidal signs and cognitive performance in patients with Alzheimer's disease enrolled in the CERAD Study. Consortium to Establish a Registry for Alzheimer's Disease. Neurology. 1997;49:70-5.
• Doody RS. Treatment of Alzheimer's disease. Neurologist. 1997;3:333-43.
• Perkins P, Annegers JF, Doody RS, Cooke N, Aday L, Vernon SW. Incidence and prevalence of dementia in a multiethnic cohort of municipal retirees. Neurology. 1997;49:44-50.
• Reisberg B, Schneider L, Doody R, Anand R, Feldman H, Haraguchi H, Kumar R, Lucca U, Mangone CA, Mohr E, Morris JC, Rogers S, Sawada T. Clinical global measures of dementia. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:8-18.
• Sabbagh MN, Lynn P, Jhingran S, Massman P, Villanueva-Meyer J, Olup J, Doody RS. Correlations between SPECT regional cerebral blood flow and psychometric testing in patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1997;9:68-74.
• Schneider LS, Olin JT, Doody RS, Clark CM, Morris JC, Reisberg B, Schmitt FA, Grundman M, Thomas RG, Ferris SH. Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord. 1997;11 Suppl 2:S22-32.
• Strite D, Massman PJ, Cooke N, Doody RS. Neuropsychological asymmetry in Alzheimer's disease: verbal versus visuoconstructional deficits across stages of dementia. J Int Neuropsychol Soc. 1997;3:420-7.
• Thal LJ, Carta A, Doody R, Leber P, Mohs R, Schneider L, Shimohama S, Silber C. Prevention protocols for Alzheimer disease. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:46-9.
• Kataki M, Winikates J, Kirkpatrick J, Doody RS. Longitudinal study of aphasia in Creutzfeldt-Jakob disease. Neuropsychiatry Neuropsychol Behav Neurol. 1996;9:284-7.
• Massman PJ, Doody RS. Hemispheric asymmetry in Alzheimer's disease is apparent in motor functioning. J Clin Exp Neuropsychol. 1996;18:110-21.
• Massman PJ, Kreiter KT, Jankovic J, Doody RS. Neuropsychological functioning in cortical-basal ganglionic degeneration: Differentiation from Alzheimer's disease. Neurology. 1996;46:720-6.
• Olin JT, Schneider LS, Doody RS, Clark CM, Ferris SH, Morris JC, Reisberg B, Schmitt FA. Clinical evaluation of global change in Alzheimer's disease: identifying consensus. J Geriatr Psychiatry Neurol. 1996;9:176-80.
• Doody RS, Massman P, Mahurin R, Law S. Positive and negative neuropsychiatric features in Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1995;7:54-60.
• Kotrla KJ, Chacko RC, Harper RG, Doody R. Clinical variables associated with psychosis in Alzheimer's disease. Am J Psychiatry. 1995;152:1377-9.
• Kotrla KJ, Chacko RC, Harper RG, Jhingran S, Doody R. SPECT findings on psychosis in Alzheimer's disease. Am J Psychiatry. 1995;152:1470-5.
• Shaibani A, Sabbagh M, Doody RS. Laughter and crying in neurologic disorders. Neuropsychiatry Neuropsychol Behav Neurol. 1994;7:243-50.
• Doody RS. A reappraisal of localization theory with reference to aphasia. Part 1: Historical considerations. Brain Lang. 1993;44:296-326.
• Doody RS. A reappraisal of localization theory with reference to aphasia. Part 2: Language theories from outside neurology. Brain Lang. 1993;44:327-48.
• Davis KL, Thal LJ, Gamzu ER, Davis CS, Woolson RF, Gracon SI, Drachman DA, Schneider LS, Whitehouse PJ, Hoover TM, et al. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group. N Engl J Med. 1992;327:1253-9.
• Doody RS, Hrachovy RA, Feher EP. Recurrent fluent aphasia associated with a seizure focus. Brain Lang. 1992;42:419-30.
• Doody RS, Jankovic J. The alien hand and related signs. J Neurol Neurosurg Psychiatry. 1992;55:806-10.
• Doody RS. Sense and non-sense: dissemination and empiricism in practice. Ethos. 1992;20:220-9.
• Feher EP, Mahurin RK, Doody RS, Cooke N, Sims J, Pirozzolo FJ. Establishing the limits of the Mini-Mental State. Examination of 'subtests'. Arch Neurol. 1992;49:87-92.
• Doody RS. Aphasia as postmodern (anthropological) discourse. J Anthropol Res. 1991;47:285-303.
• Feher EP, Doody RS, Whitehead J, Pirozzolo FJ. Progressive nonfluent aphasia with dementia: a case report. J Geriatr Psychiatry Neurol. 1991;4:236-40.
• Doody RS, Rosenfield DB. Spasmodic dysphonia associated with palatal myoclonus. Ear Nose Throat J. 1990;69:829-32.
• Feher EP, Doody R, Pirozzolo FJ, Appel SH. Mental status assessment of insight and judgment. Clin Geriatr Med. 1989;5:477-98.
• Ornish D, Scherwitz LW, Doody RS, Kesten D, McLanahan SM, Brown SE, DePuey E, Sonnemaker R, Haynes C, Lester J, McAllister GK, Hall RJ, Burdine JA, Gotto AM, Jr. Effects of stress management training and dietary changes in treating ischemic heart disease. Jama. 1983;249:54-9.
• Doody RS, Grose NP. The family medical history: assessing patient understanding of diabetes mellitus. Diabetes Care. 1981;4:285-8.