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Department of Neurology

Houston, Texas

BCM neurologists see patients through the Baylor Clinic and some of the world's leading specialty clinics.
Department of Neurology
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Poster and Platform Presentations

by PDRL Members

Faculty > Neurology >

American Neurological Association (ANA)
134th Annual Meeting in Baltimore, Maryland (Oct. 11-14, 2009)

Novel multifunctional drug D-264 for Parkinson's disease: Evidence of neuroprotective property in PD animal models induced by MPTP and lactacystin.

Li C, Biswas S, Xie WJ, Dutta AK, Le WD

Movement Disorder Society (MDS)
13th International Congress of Parkinson's Disease and Movement Disorders in Paris, France (June 7-11, 2009)

Transcription factor PITX3 in Parkinson's disease.

Le W, Nguyen D, Lin W, Rawal P, Ding Y, Xie W, Deng H, Jankovic J

17-AAG protects against rotenone-induced apoptosis in SHSY5Y cells via HSP70 induction.

Pan T, Xie W, Jankovic J, Le W

Resveratrol, a polyphenol found in red wine, protects against rotenone-induced apoptosis through autophagy induction.

Pan T, Xie W, Le W, Jankovic J

American Academy of Neurology (AAN)
61st Annual Meeting in Seattle, Washington (April 25 - May 2, 2009)

Rapamycin protects against rotenone-induced apoptosis through autophagy induction in SH-SY5Y cells.

Pan T, Xie W, Rawal P, Jankovic J, Le W

American Neurological Association (ANA)
133rd Annual Meeting in Salt Lake City, Utah (Sept. 21-24, 2008)

Short-term and long-term improvement by pramipexole in restless leg syndrome animal model.

Lou FF, Zhu W, Xie W, Ondo W, Le W

Thalamic endogenous opioids are decreased in restless legs syndrome: A post-mortem study.

Walters AS, Ondo W, Zhu W, Le WD

Progressive DA neuron degeneration induced by targeting administration of proteasome inhibitor in SN.

Xie W, Zhu W, Pan T, Jankovic J, Le W

Movement Disorder Society (MDS)
12th International Congress of Parkinson's Disease and Movement Disorders in Chicago, Illinois (June 22-26, 2008)

Expanded study of NURR1 gene expression in patients with Parkinson's disease.

Le WD, Pan T, Xie W, Huang M, Xu P, Zhu W, Zhang X, Deng H, Jankovic J

Rapamycin rescues lactacystin-induced dopaminergic neuron injury in vivo.

Pan T, Xie W, Jankovic J, Le WD

American Academy of Neurology (AAN)
60th Annual Meeting in Chicago, Illinois (April 12-19, 2008)

Role of deferoxamine and autophagy induction in rotenone-induced apoptosis.

Pan T, Li X, Xie W, Jankovic J, Le WD

Movement Disorder Society (MDS)
11th International Congress of Parkinson's Disease and Movement Disorders in Istanbul, Turkey (June 3-7, 2007)

Brain permeable iron chelators M-30 and AK-28 rescue degenerated nigral dopamine neurons in animal model of PD.

Zhu W, Pan T, Xie W, Jankovic J, Zheng H, Youdim M, Le W

American Academy of Neurology (AAN)
59th Annual Meeting in Boston, Massachusetts (April 28 - May 5, 2007)

Three parkin mutations in a family with Parkinson's disease.

Deng H, Le W, Shahed J, Jankovic J

Autophagy induction and its neuroprotection on neurotoxin-induced cell injury relevant to Parkinson's disease.

Pan T, Li X, Zhu W, Xie W, Jankovic J, Le W

Novel brain permeable iron chelators prevent lactacystin induced ubiquitn-proteasome inhibition and degeneration of nigrostrialtal dopamine neurons.

Zhu W, Pan T, Xie W, Xu P, Zheng H, Fridkin M, Jankovic J, Youdim MBH, Le W

Proteasome inhibition in substantial nigra induces sustained dopamine cells degeneration.

Zhu W, Pan T, Zhang X, Xie W, Jankovic J, Le W

8th International Conference on Alzheimer's and Parkinson's Diseases (ADPD)
Salzburg, Austria (March 14-18, 2007)

Comparison of neuroprotective and neurorescue capabilities of rasagiline and selegiline, against lactacystin induced nigrostriatal degeneration.

Zhu W, Pan T, Xie W, Xu P, Jankovic J, Youdim MBH, Le W

Movement Disorder Society (MDS)
10th International Congress of Parkinson's Disease and Movement Disorders in Kyoto, Japan (Oct. 30 - Nov. 2, 2006)

Examination of LRRK2 I2012T, G2019S, and I2020T mutations in patients with essential tremor.

Deng H, Le W, Davidson AL, Xie W, Jankovic J

Enhancement of autophagy and neuroprotection by rapamycin in lactacystin-induced injury of dopaminergic neurons.

Pan T, Kondo S, Zhu W, Xie W, Jankovic J, Le W

Spinal cord dopamine receptor expression and function in mice with 6-OHDA lesion of the A11 nucleus and dietary iron deprivation.

Zhao H, Zhu W, Pan T, Xie W, Ondo W, Le W

American Neurological Association (ANA)
131st Annual Meeting in Chicago, Illinois (Oct. 8-11, 2006)

Examination of LRRK2 I2012T, G2019S, and I2020T mutations in patients with essential tremor.

Deng H, Le W, Guo Y, Hunter CB, Xie W, Huang M, Jankovic J

A Mexican pedigree with Parkinson's disease, essential tremor and bell's palsy associated with parkin but not HS1BP3 gene mutation.

Deng H, Le W, Hunter CB, Xie W, Mejia N, Jankovic J

Genetic analysis of the SLITRK1 gene in caucasian patients with Tourette syndrome.

Deng H, Le W, Xie W, Jankovic J

American Academy of Neurology (AAN)
58th Annual Meeting in San Diego, California (April 1-8, 2006)

Nurrl deficiency predisposes to apoptosis induced by lactacystin in SH-SY5Y cells in vitro.

Pan T, Xie W, Deng H, Zhao H, Jankovic J

American Academy of Neurology (AAN)
57th Annual Meeting in Miami Beach, Florida (April 9-16, 2005)

Genetic analysis of G309D and W4370PA mutations of PINK1 in Parkinson's disease.

Deng H, Le W, Zhang X, Pan T, Jankovic J

HSP70 inducer VPA inhibits rotenone-induced apoptosis in SH-SY5Y cells.

Pan T, Xie W, Jankovic J, Le W

Movement Disorder Society (MDS)
9th International Congress of Parkinson's Disease and Movement Disorders in New Orleans, Louisiana (March 5-8, 2005)

Small interfering RNA (SiRNA) targeting the PINK1 induces apoptosisin human SH-SY5Y cells.

Deng H, Jankovic J, Pan T, Xie W, Le W

Reduced NURR1 gene expression affects expression of dopaminergic phenotypic markers and Parkinson's disease-related genes.

Deng H, Jankovic J, Xie W, Pan T, Le W

Movement Disorder Society (MDS)
8th International Congress of Parkinson's Disease and Movement Disorders in Rome, Italy (June 13-17, 2004)

Nurr1 gene targeting therapy for Parkinson disease.

Le W, Jiang Q, Xie W, Hintermann S, Jankovic J

The pharmacological and biological effects of pramipexole on dopamine neuron associated genes: DAT, VMAT-2, and Nurr1.

Pan T, Xie W, Jankovic J, Le W

American Academy of Neurology (AAN)
56th Annual Meeting in San Francisco, California (April 24 - May 1, 2004)

Effects of ropinirole on progression of parkinsonism in Nurr1-deficient mice and its underlying mechanisms.

Jiang C, Pan T, Jankovic J, Le W

Dopaminergic properties and anti-parkinsonian effects of IPX750 in rodent models of Parkinson's disease.

Jiang C, Wan X, Jankovic J, Christian S, Sundsmo J, Le W

The pharmacological and biological effects of pramipexole on dopamine transporter.

Pan T, Jankovic J, Le W

Decreased Nurr1 mRNA in peripheral blood lymphocytes in Parkinson's disease.

Pan T, Xie W, Jankovic J, Le W

Movement Disorder Society (MDS)
7th International Congress of Parkinson's Disease and Movement Disorders in Miami, Florida (Nov. 10-14, 2002)

Reduced Nurr1 expression increases the susceptibility to dopaminergic toxins via nitric oxide.

Le W, Imam SZ, Xie W, Ali S, Jankovic J

Upregulation of Nurr1 gene expression by dopamine receptor agonist pramipexole in human neuroblastoma SHSY-5Y cells.

Pan TH, Xu PY, Xie WJ, Hunter C, Jankovic J, Le WD