Eroboghene E. Ubogu, M.D.

Assistant Professor of Neurology

Director, Neuromuscular Immunopathology
Research Laboratory

Clinical Service Area

Neurology

Specialty

General Neurology
Neuromuscular Disease
Electrodiagnostic Medicine
Neuromuscular Immunology / Inflammation

Board Certification

American Board of Psychiatry and Neurology, Neurology
American Board of Psychiatry and Neurology, Clinical Neurophysiology
American Board of Psychiatry and Neurology, Neuromuscular Medicine

Clinic Appointments

713-798-5975

Consult

713-798-5975

Medical School

M.D., Imperial College School of Medicine, University of London, United Kingdom

Internship

Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH

Residency

Neurology, University Hospitals of Cleveland/Case Western Reserve University, Cleveland, OH

Fellowship

Clinical Neurophysiology and Neuromuscular Disorders, Emory University School of Medicine, Atlanta, GA
Neuroscience, Cleveland Clinic Foundation, Cleveland, OH

Clinical Interests

Neuromuscular disorders: Peripheral neuropathies (acquired and inherited), Myopathies (acquired and inherited) and Disorders of Neuromuscular Junction. Special interest in autoimmune neuromuscular disorders: inflammatory neuropathies (such as Guillain-Barré Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathies) and idiopathic inflammatory myopathies, Neuromuscular pathology, Electrodiagnostic Medicine (routine nerve conduction and needle electromyographic studies, repetitive nerve stimulation, single fiber electromyographic studies and other special techniques)

Clinic Location

General Neurology and Neuromuscular Medicine:
Baylor Neurology
Smith Tower
6550 Fannin, Suite 1801
Houston, Texas 77030

Electrodiagnostic Medicine:
Baylor Neurology
Neurosensory Building
6501 Fannin, NB336
Houston, Texas 77030

Research Interests

Neuromuscular Inflammation: Mechanisms of leukocyte entry into peripheral nerve and muscle in autoimmune disease and during immune surveillance using human in vitro transmigration and in vivo animal models.

Journal Publications
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DeBrosse S, Ubogu EE, Yaniglos S, Hassan MO, Leigh RJ. Dynamic properties of eye movements in mitochondrial chronic progressive external ophthalmoplegia. Eye. 2009;23:382-8.

Man S, Ubogu EE, Williams KA, Tucky B, Callahan MK, Ransohoff RM. Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration. Clin Dev Immunol. 2008;2008:384982.

Lai WW, Ubogu EE. Chronic inflammatory demyelinating polyradiculoneuropathy presenting as cauda equina syndrome in a diabetic. J Neurol Sci. 2007;260:267-70.

Man S, Ubogu EE, Ransohoff RM. Inflammatory cell migration into the central nervous system: a few new twists on an old tale. Brain Pathol. 2007;17:243-50.

Ransohoff RM, Man S, Ubogu EE. Doing the locomotion with the multistep paradigm. Blood. 2007;109:1342-1343.

Mahad D, Callahan MK, Williams KA, Ubogu EE, Kivisakk P, Tucky B, Kidd G, Kingsbury GA, Chang A, Fox RJ, Mack M, Sniderman MB, Ravid R, Staugaitis SM, Stins MF, Ransohoff RM. Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis. Brain. 2006;129:212-23.

Ubogu EE, Benatar M. Electrodiagnostic criteria for carpal tunnel syndrome in axonal polyneuropathy. Muscle Nerve. 2006;33:747-52.

Ubogu EE, Callahan MK, Tucky BH, Ransohoff RM. CCR5 expression on monocytes and T cells: modulation by transmigration across the blood-brain barrier in vitro. Cell Immunol. 2006;243:19-29.

Ubogu EE, Callahan MK, Tucky BH, Ransohoff RM. Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation. J Neuroimmunol. 2006;179:132-44.

Ubogu EE, Cossoy MB, Ransohoff RM. The expression and function of chemokines involved in CNS inflammation. Trends Pharmacol Sci. 2006;27:48-55.

Ubogu EE. Complete innervation of extensor digitorum brevis by accessory peroneal nerve. Neuromuscul Disord. 2005;15:562-4.

Ubogu EE, Hong ST, Akman HO, Dimauro S, Katirji B, Preston DC, Shapiro BE. Adult polyglucosan body disease: a case report of a manifesting heterozygote. Muscle Nerve. 2005;32:675-81.

Ubogu EE, Zaidat OO. Intracranial arterial dolichoectasia is associated with enlarged descending thoracic aorta. Neurology. 2005;65:1681-2; author reply 1681-2.

Ubogu EE, Verrees MA, Sunshine JL, Zaidat OO. Clinical and radiological features of symptomatic cerebral perfusion failure due to carotid artery occlusion surgically corrected by extracranialintracranial bypass surgery. J Neurol. 2004;251:613-6.

Ubogu EE, Zaidat OO. Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study. J Neurol Neurosurg Psychiatry. 2004;75:22-6.

Zaidat OO, Zahuranec DB, Ubogu EE, Fernandes-Filho JA, Suarez JI, Sunshine JL, Tarr RW, Mirarchi S, Nour SG, Selman WR, Landis DM. Asymptomatic middle cerebral artery stenosis diagnosed by magnetic resonance angiography. Neuroradiology. 2004;46:49-53.

Ubogu EE, Katirji B. Mirtazapine-induced serotonin syndrome. Clin Neuropharmacol. 2003;26:54-7.

Ubogu EE, Lindenberg JR, Werz MA. Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infection. Reg Anesth Pain Med. 2003;28:470-4.

Ubogu EE, Sagar SM, Lerner AJ, Maddux BN, Suarez JI, Werz MA. Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity. Epilepsy Behav. 2003;4:70-5.

Ubogu EE, Chase CM, Verrees MA, Metzger AK, Zaidat OO. Cervicomedullary junction compression caused by vertebral artery dolichoectasia and requiring surgical treatment. Case report. J Neurosurg. 2002;96:140-3.

Ubogu EE, Zaidat OO. Rectus sheath hematoma complicating percutaneous endoscopic gastrostomy. Surg Laparosc Endosc Percutan Tech. 2002;12:430-2.

Zaidat OO, Ubogu EE. Otalgia as the sole presenting manifestation of subdural hematoma. Am J Otolaryngol. 2002;23:177-80.

Zaidat OO, Ubogu EE, Lerner AJ. Recurrent transient ischemic attacks as the initial presenting manifestation of type A aortic dissection. Ann Vasc Surg. 2002;16:676-8.

Ubogu E. Amaurosis fugax associated with phencyclidine inhalation. Eur Neurol. 2001;46:98-9.

Ubogu EE, Kaminski HJ. The preferential involvement of extraocular muscles by myasthenia gravis. Neuro-Ophthalmology. 2001;25:219 - 228.

Ubogu EE, Zaidat OO, Suarez JI. Acute motor-sensory axonal neuropathy associated with active systemic lupus erythematosus and anticardiolipin antibodies. J Clin Rheumatol. 2001;7:326-31.

Books and Volumes
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Ubogu EE. Neurology oral boards review: a concise and systematic approach to clinical practice. Totowa (NJ): Humana Press; 2005.

Book Chapters and Other Publications
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Benatar MG, Ubogu EE. Lambert Eaton myasthenic syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 10th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2008. p. 493.

Benatar MG, Ubogu EE. Guillain-barré syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 10th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2008. p. 369-370.

Ubogu EE. Friedreich’s ataxia. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 10th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2008. p. 139-141.

Ubogu EE. Tabes dorsalis. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 10th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2008. p. 879.

Ubogu EE, Benatar MG. Neuroleptic malignant syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 10th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2008. p. 609.

Ubogu EE, Ruff RL. Neuromuscular junction physiology and pathophysiology. In: Kaminski HJ, editor. Current clinical neurology: myasthenia gravis and related disorders. 2nd ed. Totowa (NJ): Humana Press; 2008. (in press). p. 127-144.

Ubogu EE. Lambert Eaton myasthenic syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 9th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 491.

Ubogu EE. Guillain-barré syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 9th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 367-368.

Ubogu EE. Friedreich’s ataxia. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 9th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 337.

Ubogu EE. Neuroleptic malignant syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 9th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 603.

Ubogu EE. Guillain-barré syndrome. In: Wachtel TJ, editor. Geriatric clinical advisor: instant diagnosis and treatment. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 88-89.

Ubogu EE. Tabes dorsalis. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 9th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 870.

Ubogu EE, Ransohoff RM. Chemokines in central nervous system inflammation: relevance to multiple sclerosis. In: Cohen JA, Rudick RA, editors. Multiple sclerosis therapeutics. 3rd ed. London: Martin Dunitz (Taylor & Francis Group); 2007. p. 629-644.

Wachtel TJ, Ubogu EE. Guillain-barré syndrome. In: Wachtel TJ, Fretwell M, editors. Practical guide to the care of the geriatric patient. 3rd ed. Philadelphia: Mosby Inc. (Elsevier Science); 2007. p. 88-89.

Ubogu EE. Lambert Eaton myasthenic syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 8th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2006. p. 471.

Ubogu EE. Neuroleptic malignant syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 8th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2006. p. 572.

Ubogu EE. Tabes dorsalis. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 8th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2006. p. 821.

Ubogu EE. Friedreich’s ataxia. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 8th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2006. p. 327.

Ubogu EE. Guillain-barré syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 8th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2006. p. 355-356.

Ubogu EE. Tabes dorsalis. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 7th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2005. p. 800.

Ubogu EE. Neuroleptic malignant syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 7th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2005. p. 561.

Ubogu EE. Lambert Eaton myasthenic syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 7th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2005. p. 463.

Ubogu EE. Guillain-barré syndrome. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 7th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2005. p. 349-350.

Ubogu EE. Friedreich’s ataxia. In: Ferri FF, editor. Ferri’s clinical advisor: instant diagnosis and treatment. 7th ed. Philadelphia: Mosby Inc. (Elsevier Science); 2005. p. 319.

Ubogu EE, Kaminski HJ, Ruff RL. Endocrine myopathy (hyper and hypofunction of adrenal, thyroid, pituitary and parathyroid glands and Iatrogenic steroid myopathy). In: Engel A, Franzini-Amstrong C, editors. Myology. 3rd ed. New York: McGraw-Hill; 2004. p. 1713-1738.

Ubogu EE, Leigh RJ. Neuro-ophthalmological evaluation of the ICU patient. In: Suarez JI, editor. Critical care neurology and neurosurgery. Totowa (NJ): Humana Press; 2004. p. 533-540.

Ubogu EE. Epilepsy. In: Lerner A, Zaidat O, editors. The little black book of neurology. 4th ed. St Louis: Mosby Inc. (Elsevier Science); 2002. p. 127-144.