William G. Ondo, M.D.

Professor of Neurology

Clinical Service Area

Neurology

Specialty

Parkinson's Disease
Tremors
Movement Disorders

Board Certification

American Board of Psychiatry and Neurology, Neurology

Clinic Appointments

713-798-7438

Consult

713-798-7438

Medical School

Medical College of Virginia Hospitals, Richmond, VA

Internship

Internal Medicine, University of North Carolina, Chapel Hill, NC

Residency

Neurology, Duke University Medical Center, Durham, NC

Fellowship

Movement Disorders, Baylor College of Medicine, Houston, TX

Clinical Interests

Restless Legs Syndrome, Tremor, Dystonia treatment with botulinum toxin, Parkinsons Disease and related parkinsonian conditions, Tourettes Syndrome, Huntingtons Disease, other disorders of movement and neurodegenerative disease

Clinic Location

Baylor Neurology
Smith Tower
6550 Fannin, Suite 1801
Houston, Texas 77030

Research Interests

Restless legs syndrome, Parkinson's disease, tremor, and the use of botulinum toxins

Publications
Collapse All | Expand All

Ferrara JM, Adam OR, Ondo WG. Treatment of fragile-X-associated tremor/ataxia syndrome with deep brain stimulation. Mov Disord. 2009;24:149-51.
Hauser RA, Lew MF, Hurtig HI, Ondo WG, Wojcieszek J, Fitzer-Attas CJ. Long-term outcome of early versus delayed rasagiline treatment in early Parkinson's disease. Mov Disord. 2009;24:564-73.
LeWitt PA, Ondo WG, Van Lunen B, Bottini PB. Open-label study assessment of safety and adverse effects of subcutaneous apomorphine injections in treating "off" episodes in advanced Parkinson disease. Clin Neuropharmacol. 2009;32:89-93.
Ondo WG. Restless legs syndrome. Neurol Clin. 2009;27:779-99, vii.
Sitburana O, Ondo WG. Brain magnetic resonance imaging (MRI) in parkinsonian disorders. Parkinsonism Relat Disord. 2009;15:165-74.
Walters AS, Ondo WG, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin Enacarbil in Restless Legs Syndrome: A Phase 2b, 2-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Clin Neuropharmacol. 2009;:.
Walters AS, Ondo WG, Zhu W, Le W. Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study. J Neurol Sci. 2009;279:62-5.
Frank S, Ondo W, Fahn S, Hunter C, Oakes D, Plumb S, Marshall F, Shoulson I, Eberly S, Walker F, Factor S, Hunt V, Shinaman A, Jankovic J. A study of chorea after tetrabenazine withdrawal in patients with Huntington disease. Clin Neuropharmacol. 2008;31:127-33.
Moore ST, Macdougall HG, Gracies JM, Ondo WG. Locomotor response to levodopa in fluctuating Parkinson's disease. Exp Brain Res. 2008;184:469-78.
Moore ST, Macdougall HG, Ondo WG. Ambulatory monitoring of freezing of gait in Parkinson's disease. J Neurosci Methods. 2008;167:340-8.
Ondo WG, Jong D, Davis A. Comparison of weight gain in treatments for Tourette syndrome: tetrabenazine versus neuroleptic drugs. J Child Neurol. 2008;23:435-7.
Ondo WG, Lai D. Predictors of impulsivity and reward seeking behavior with dopamine agonists. Parkinsonism Relat Disord. 2008;14:28-32.
Ondo WG, Perkins T, Swick T, Hull KL, Jr., Jimenez JE, Garris TS, Pardi D. Sodium oxybate for excessive daytime sleepiness in Parkinson disease: an open-label polysomnographic study. Arch Neurol. 2008;65:1337-40.
Satija P, Ondo WG. Restless legs syndrome: pathophysiology, diagnosis and treatment. CNS Drugs. 2008;22:497-518.
Sitburana O, Ondo WG. Task-specific focal hand dystonia in a professional pistol-shooter. Clin Neurol Neurosurg. 2008;110:423-4.
Sitburana O, Rountree S, Ondo WG. Weight change in Parkinson and Alzheimer patients taking atypical antipsychotic drugs. J Neurol Sci. 2008;272:77-82.
Truong D, Comella C, Fernandez HH, Ondo WG. Efficacy and safety of purified botulinum toxin type A (Dysport) for the treatment of benign essential blepharospasm: a randomized, placebo-controlled, phase II trial. Parkinsonism Relat Disord. 2008;14:407-14.
Chaudhuri KR, Martinez-Martin P, Brown RG, Sethi K, Stocchi F, Odin P, Ondo W, Abe K, Macphee G, Macmahon D, Barone P, Rabey M, Forbes A, Breen K, Tluk S, Naidu Y, Olanow W, Williams AJ, Thomas S, Rye D, et al. The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study. Mov Disord. 2007;22:1901-11.
Kenney C, Simpson R, Hunter C, Ondo W, Almaguer M, Davidson A, Jankovic J. Short-term and long-term safety of deep brain stimulation in the treatment of movement disorders. J Neurosurg. 2007;106:621-5.
Martinez-Martin P, Schapira AH, Stocchi F, Sethi K, Odin P, MacPhee G, Brown RG, Naidu Y, Clayton L, Abe K, Tsuboi Y, MacMahon D, Barone P, Rabey M, Bonuccelli U, Forbes A, Breen K, Tluk S, Olanow CW, Thomas S, et al. Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients. Mov Disord. 2007;22:1623-9.
May S, Gilman S, Sowell BB, Thomas RG, Stern MB, Colcher A, Tanner CM, Huang N, Novak P, Reich SG, Jankovic J, Ondo WG, Low PA, Sandroni P, Lipp A, Marshall FJ, Wooten F, Shults CW. Potential outcome measures and trial design issues for multiple system atrophy. Mov Disord. 2007;22:2371-7.
Moore ST, MacDougall HG, Gracies JM, Cohen HS, Ondo WG. Long-term monitoring of gait in Parkinson's disease. Gait Posture. 2007;26:200-7.
Ondo WG. Zonisamide for essential tremor. Clin Neuropharmacol. 2007;30:345-9.
Ondo WG. Placebo response in Parkinson trials using patient diaries: sites do matter. Clin Neuropharmacol. 2007;30:301-4.
Ondo WG, Meilak C, Vuong KD. Predictors of battery life for the Activa Soletra 7426 Neurostimulator. Parkinsonism Relat Disord. 2007;13:240-2.
Ondo WG, Mejia NI, Hunter CB. A pilot study of the clinical efficacy and safety of memantine for Huntington's disease. Parkinsonism Relat Disord. 2007;13:453-4.
Ondo WG, Satija P. Withdrawal of visual feedback improves micrographia in Parkinson's disease. Mov Disord. 2007;22:2130-1.
Ondo WG, Sethi KD, Kricorian G. Selegiline orally disintegrating tablets in patients with Parkinson disease and 'wearing off' symptoms. Clin Neuropharmacol. 2007;30:295-300.
Ondo WG, Zhao HR, Le WD. Animal models of restless legs syndrome. Sleep Med. 2007;8:344-8.
Ozelius LJ, Foroud T, May S, Senthil G, Sandroni P, Low PA, Reich S, Colcher A, Stern MB, Ondo WG, Jankovic J, Huang N, Tanner CM, Novak P, Gilman S, Marshall FJ, Wooten GF, Chelimsky TC, Shults CW. G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy. Mov Disord. 2007;22:546-9.
Qu S, Le W, Zhang X, Xie W, Zhang A, Ondo WG. Locomotion is increased in a11-lesioned mice with iron deprivation: a possible animal model for restless legs syndrome. J Neuropathol Exp Neurol. 2007;66:383-8.
Stacy MA, Elble RJ, Ondo WG, Wu SC, Hulihan J. Assessment of interrater and intrarater reliability of the Fahn-Tolosa-Marin Tremor Rating Scale in essential tremor. Mov Disord. 2007;22:833-8.
Zhao H, Zhu W, Pan T, Xie W, Zhang A, Ondo WG, Le W. Spinal cord dopamine receptor expression and function in mice with 6-OHDA lesion of the A11 nucleus and dietary iron deprivation. J Neurosci Res. 2007;85:1065-76.
Chaudhuri KR, Martinez-Martin P, Schapira AH, Stocchi F, Sethi K, Odin P, Brown RG, Koller W, Barone P, MacPhee G, Kelly L, Rabey M, MacMahon D, Thomas S, Ondo W, Rye D, Forbes A, Tluk S, Dhawan V, Bowron A, et al. International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study. Mov Disord. 2006;21:916-23.
Deng H, Le WD, Hunter CB, Ondo WG, Guo Y, Xie WJ, Jankovic J. Heterogeneous phenotype in a family with compound heterozygous parkin gene mutations. Arch Neurol. 2006;63:273-7.
Friedman JH, Berman RM, Goetz CG, Factor SA, Ondo WG, Wojcieszek J, Carson WH, Marcus RN. Open-label flexible-dose pilot study to evaluate the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease. Mov Disord. 2006;21:2078-81.
Lang AE, Houeto JL, Krack P, Kubu C, Lyons KE, Moro E, Ondo W, Pahwa R, Poewe W, Troster AI, Uitti R, Voon V. Deep brain stimulation: preoperative issues. Mov Disord. 2006;21 Suppl 14:S171-96.
Ondo W. VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor. Parkinsonism Relat Disord. 2006;12:113-4.
Ondo WG. Essential tremor: treatment options. Curr Treat Options Neurol. 2006;8:256-67.
Ondo WG, Almaguer M, Cohen H. Computerized posturography balance assessment of patients with bilateral ventralis intermedius nuclei deep brain stimulation. Mov Disord. 2006;21:2243-7.
Ondo WG, Jankovic J, Connor GS, Pahwa R, Elble R, Stacy MA, Koller WC, Schwarzman L, Wu SC, Hulihan JF. Topiramate in essential tremor: a double-blind, placebo-controlled trial. Neurology. 2006;66:672-7.
Ondo WG, Lai D. Association between restless legs syndrome and essential tremor. Mov Disord. 2006;21:515-8.
Ondo WG, Silay Y, Almaguer M, Jankovic J. Subthalamic deep brain stimulation in patients with a previous pallidotomy. Mov Disord. 2006;21:1252-4.
Ondo WG, Silay YS. Intravenous flumazenil for Parkinson's disease: a single dose, double blind, placebo controlled, cross-over trial. Mov Disord. 2006;21:1614-7.
Pahwa R, Factor SA, Lyons KE, Ondo WG, Gronseth G, Bronte-Stewart H, Hallett M, Miyasaki J, Stevens J, Weiner WJ. Practice Parameter: treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006;66:983-95.
Pahwa R, Lyons KE, Wilkinson SB, Simpson RK, Jr., Ondo WG, Tarsy D, Norregaard T, Hubble JP, Smith DA, Hauser RA, Jankovic J. Long-term evaluation of deep brain stimulation of the thalamus. J Neurosurg. 2006;104:506-12.
Qu S, Ondo WG, Zhang X, Xie WJ, Pan TH, Le WD. Projections of diencephalic dopamine neurons into the spinal cord in mice. Exp Brain Res. 2006;168:152-6.
Sitburana O, Ondo WG. Tetrabenazine for hyperglycemic-induced hemichorea-hemiballismus. Mov Disord. 2006;21:2023-5.
Ondo WG. Restless legs syndrome. Neurol Clin. 2005;23:1165-85, viii.
Ondo WG. Methadone for refractory restless legs syndrome. Mov Disord. 2005;20:345-8.
Ondo WG, Bronte-Stewart H. The North American survey of placement and adjustment strategies for deep brain stimulation. Stereotact Funct Neurosurg. 2005;83:142-7.
Ondo WG, Fayle R, Atassi F, Jankovic J. Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial. J Neurol Neurosurg Psychiatry. 2005;76:1636-9.
Ondo WG, Gollomp S, Galvez-Jimenez N. A pilot study of botulinum toxin A for headache in cervical dystonia. Headache. 2005;45:1073-7.
Ondo WG, Lai D. Olfaction testing in patients with tremor-dominant Parkinson's disease: is this a distinct condition? Mov Disord. 2005;20:471-5.
Ondo WG, Tintner R, Voung KD, Lai D, Ringholz G. Double-blind, placebo-controlled, unforced titration parallel trial of quetiapine for dopaminergic-induced hallucinations in Parkinson's disease. Mov Disord. 2005;20:958-63.
Ondo WG, Wang A, Thomas M, Vuong KD. Evaluating factors that can influence spirography ratings in patients with essential tremor. Parkinsonism Relat Disord. 2005;11:45-8.
Zesiewicz TA, Elble R, Louis ED, Hauser RA, Sullivan KL, Dewey RB, Jr., Ondo WG, Gronseth GS, Weiner WJ. Practice parameter: therapies for essential tremor: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2005;64:2008-20.
Chen S, Ondo WG, Rao S, Li L, Chen Q, Wang Q. Genomewide linkage scan identifies a novel susceptibility locus for restless legs syndrome on chromosome 9p. Am J Hum Genet. 2004;74:876-85.
Ondo W, Romanyshyn J, Vuong KD, Lai D. Long-term treatment of restless legs syndrome with dopamine agonists. Arch Neurol. 2004;61:1393-7.
Ondo WG, Hunter C, Moore W. A double-blind placebo-controlled trial of botulinum toxin B for sialorrhea in Parkinson's disease. Neurology. 2004;62:37-40.
Ondo WG, Jimenez JE, Vuong KD, Jankovic J. An open-label pilot study of levetiracetam for essential tremor. Clin Neuropharmacol. 2004;27:274-7.
Ondo WG, Vuong KD, Derman HS. Botulinum toxin A for chronic daily headache: a randomized, placebo-controlled, parallel design study. Cephalalgia. 2004;24:60-5.
Sanghera MK, Grossman RG, Kalhorn CG, Hamilton WJ, Ondo WG, Jankovic J. Basal ganglia neuronal discharge in primary and secondary dystonia. Adv Neurol. 2004;94:29-36.
Walters AS, Ondo WG, Dreykluft T, Grunstein R, Lee D, Sethi K. Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study. Mov Disord. 2004;19:1414-23.
Connor JR, Boyer PJ, Menzies SL, Dellinger B, Allen RP, Ondo WG, Earley CJ. Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome. Neurology. 2003;61:304-9.
Handforth A, Ondo WG, Tatter S, Mathern GW, Simpson RK, Jr., Walker F, Sutton JP, Hubble JP, Jankovic J. Vagus nerve stimulation for essential tremor: a pilot efficacy and safety trial. Neurology. 2003;61:1401-5.
Lyons KE, Pahwa R, Comella CL, Eisa MS, Elble RJ, Fahn S, Jankovic J, Juncos JL, Koller WC, Ondo WG, Sethi KD, Stern MB, Tanner CM, Tintner R, Watts RL. Benefits and risks of pharmacological treatments for essential tremor. Drug Saf. 2003;26:461-81.
Oliveira SA, Scott WK, Martin ER, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Ondo WG, Allen FH, Jr., Scott BL, Goetz CG, Small GW, Mastaglia F, Stajich JM, Zhang F, Booze MW, Winn MP, et al. Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. Ann Neurol. 2003;53:624-9.
Oliveira SA, Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons KE, Pahwa R, Stern MB, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Scott BL, Goetz CG, Small GW, Mastaglia FL, Stajich JM, Zhang F, Booze MW, et al. Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. Arch Neurol. 2003;60:975-80.
Ondo W. Gait and balance disorders. Med Clin North Am. 2003;87:793-801, viii.
Ondo WG, Hunter C. Flumazenil, a GABA antagonist, may improve features of Parkinson's disease. Mov Disord. 2003;18:683-5.
Ondo WG, Sutton L, Dat Vuong K, Lai D, Jankovic J. Hearing impairment in essential tremor. Neurology. 2003;61:1093-7.
Sanghera MK, Grossman RG, Kalhorn CG, Hamilton WJ, Ondo WG, Jankovic J. Basal ganglia neuronal discharge in primary and secondary dystonia in patients undergoing pallidotomy. Neurosurgery. 2003;52:1358-70; discussion 1370-3.
van der Walt JM, Martin ER, Scott WK, Zhang F, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Goetz CG, Small GW, Mastaglia F, et al. Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. Neurology. 2003;60:1189-91.
van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Goetz CG, Small GW, Mastaglia F, et al. Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet. 2003;72:804-11.
Ondo W. Epidemiology of restless legs syndrome. Sleep Med. 2002;3 Suppl:S13-5.
Ondo WG, Chan LL, Levy JK. Vascular parkinsonism: clinical correlates predicting motor improvement after lumbar puncture. Mov Disord. 2002;17:91-7.
Ondo WG, Levy JK, Vuong KD, Hunter C, Jankovic J. Olanzapine treatment for dopaminergic-induced hallucinations. Mov Disord. 2002;17:1031-5.
Ondo WG, Tintner R, Thomas M, Jankovic J. Tetrabenazine treatment for Huntington's disease-associated chorea. Clin Neuropharmacol. 2002;25:300-2.
Ondo WG, Verma A. Physiological assessment of paroxysmal dystonia secondary to subacute sclerosing panencephalitis. Mov Disord. 2002;17:154-7.
Ondo WG, Vuong KD, Jankovic J. Exploring the relationship between Parkinson disease and restless legs syndrome. Arch Neurol. 2002;59:421-4.
Hanna PA, Ratkos L, Ondo WG, Jankovic J. Switching from pergolide to pramipexole in patients with Parkinson's disease. J Neural Transm. 2001;108:63-70.
Hou JG, Ondo W, Jankovic J. Intrathecal baclofen for dystonia. Mov Disord. 2001;16:1201-2.
Jankovic J, Lai EC, Ondo WG, Roberts-Warrior D, Olson SL, Krauss JK, Grossman RG. Effects of pallidotomy on gait and balance. Adv Neurol. 2001;87:271-81.
Krauss JK, Simpson RK, Jr., Ondo WG, Pohle T, Burgunder JM, Jankovic J. Concepts and methods in chronic thalamic stimulation for treatment of tremor: technique and application. Neurosurgery. 2001;48:535-41; discussion 541-3.
Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Goetz CG, Small GW, Masterman D, Mastaglia F, Laing NG, Stajich JM, et al. Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. Jama. 2001;286:2245-50.
Ondo W, Almaguer M, Jankovic J, Simpson RK. Thalamic deep brain stimulation: comparison between unilateral and bilateral placement. Arch Neurol. 2001;58:218-22.
Ondo W, Dat Vuong K, Almaguer M, Jankovic J, Simpson RK. Thalamic deep brain stimulation: effects on the nontarget limbs. Mov Disord. 2001;16:1137-42.
Ondo WG, Dat Vuong K, Khan H, Atassi F, Kwak C, Jankovic J. Daytime sleepiness and other sleep disorders in Parkinson's disease. Neurology. 2001;57:1392-6.
Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Goetz CG, Small GW, Masterman D, Mastaglia F, Laing NG, Stajich JM, Slotterbeck B, et al. Complete genomic screen in Parkinson disease: evidence for multiple genes. Jama. 2001;286:2239-44.
Tan EK, Nagamitsu S, Matsuura T, Khajavi M, Jankovic J, Ondo W, Ashizawa T. Alcohol dehydrogenase polymorphism and Parkinson's disease. Neurosci Lett. 2001;305:70-2.
Tan EK, Ondo WG. Motor restlessness. Int J Clin Pract. 2001;55:320-2.
Yoshor D, Hamilton WJ, Ondo W, Jankovic J, Grossman RG. Comparison of thalamotomy and pallidotomy for the treatment of dystonia. Neurosurgery. 2001;48:818-24; discussion 824-6.
Lai EC, Jankovic J, Krauss JK, Ondo WG, Grossman RG. Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease. Neurology. 2000;55:1218-22.
Ondo W, Hunter C, Vuong KD, Schwartz K, Jankovic J. Gabapentin for essential tremor: a multiple-dose, double-blind, placebo-controlled trial. Mov Disord. 2000;15:678-82.
Ondo W, Tan EK, Mansoor J. Rheumatologic serologies in secondary restless legs syndrome. Mov Disord. 2000;15:321-3.
Ondo W, Warrior D, Overby A, Calmes J, Hendersen N, Olson S, Jankovic J. Computerized posturography analysis of progressive supranuclear palsy: a case-control comparison with Parkinson's disease and healthy controls. Arch Neurol. 2000;57:1464-9.
Ondo WG, Ben-Aire L, Jankovic J, Lai E, Contant C, Grossman R. Weight gain following unilateral pallidotomy in Parkinson's disease. Acta Neurol Scand. 2000;101:79-84.
Ondo WG, He Y, Rajasekaran S, Le WD. Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats: a possible model for restless legs syndrome. Mov Disord. 2000;15:154-8.
Ondo WG, Hunter C, Vuong KD, Jankovic J. The pharmacokinetic and clinical effects of tolcapone on a single dose of sublingual apomorphine in Parkinson's disease. Parkinsonism Relat Disord. 2000;6:237-240.
Ondo WG, Vuong KD, Wang Q. Restless legs syndrome in monozygotic twins: clinical correlates. Neurology. 2000;55:1404-6.
Tan EK, Jankovic J, Ondo W. Bruxism in Huntington's disease. Mov Disord. 2000;15:171-3.
Tan EK, Ondo W. Clinical characteristics of pramipexole-induced peripheral edema. Arch Neurol. 2000;57:729-32.
Tan EK, Ondo W. Restless legs syndrome: clinical features and treatment. Am J Med Sci. 2000;319:397-403.
Jankovic J, Schwartz KS, Ondo W. Re-emergent tremor of Parkinson's disease. J Neurol Neurosurg Psychiatry. 1999;67:646-50.
Ondo W. Ropinirole for restless legs syndrome. Mov Disord. 1999;14:138-40.
Ondo W, Hunter C, Almaguer M, Gancher S, Jankovic J. Efficacy and tolerability of a novel sublingual apomorphine preparation in patients with fluctuating Parkinson's disease. Clin Neuropharmacol. 1999;22:1-4.
Ondo W, Hunter C, Almaguer M, Jankovic J. A novel sublingual apomorphine treatment for patients with fluctuating Parkinson's disease. Mov Disord. 1999;14:664-8.
Ondo WG, Hanna PA, Jankovic J. Tetrabenazine treatment for tardive dyskinesia: assessment by randomized videotape protocol. Am J Psychiatry. 1999;156:1279-81.
Scott WK, Yamaoka LH, Stajich JM, Scott BL, Vance JM, Roses AD, Pericak-Vance MA, Watts RL, Nance M, Hubble J, Koller W, Stern MB, Colcher A, Allen FH, Jr., Hiner BC, Jankovic J, Ondo W, Laing NG, Mastaglia F, Goetz C, et al. The alpha-synuclein gene is not a major risk factor in familial Parkinson disease. Neurogenetics. 1999;2:191-2.
Becker PM, Ondo W, Sharon D. Encouraging initial response of restless legs syndrome to pramipexole. Neurology. 1998;51:1221-3.
Ondo W, Jankovic J, Schwartz K, Almaguer M, Simpson RK. Unilateral thalamic deep brain stimulation for refractory essential tremor and Parkinson's disease tremor. Neurology. 1998;51:1063-9.
Ondo WG, Desaloms JM, Jankovic J, Grossman RG. Pallidotomy for generalized dystonia. Mov Disord. 1998;13:693-8.
Ondo WG, Harris C. Toward optimal health: the experts respond to Parkinson's disease. Interview by Jodi Godfrey Meisler. J Womens Health. 1998;7:957-62.
Ondo WG, Jankovic J, Lai EC, Sankhla C, Khan M, Ben-Arie L, Schwartz K, Grossman RG, Krauss JK. Assessment of motor function after stereotactic pallidotomy. Neurology. 1998;50:266-70.
Ondo W. Lingual dystonia following electrical injury. Mov Disord. 1997;12:253.
Ondo W, Jankovic J. Restless legs syndrome: clinicoetiologic correlates. Neurology. 1996;47:1435-41.
Ondo WG, Delong GR. Dandy-Walker syndrome presenting as opisthotonus: proposed pathophysiology. Pediatr Neurol. 1996;14:165-8.
Perkins AT, Ondo W. When to worry about headache. Head pain as a clue to intracranial disease. Postgrad Med. 1995;98:197-201, 204-8.
Ondo WG, Hurwitz BJ. Tardive dyskinesia and pseudo-parkinsonism. In a nursing home patient who itched. N C Med J. 1993;54:605-7.

Books and Volumes
Collapse All | Expand All

Ondo WG, Chaudhuri R, editors. Handbook of movement disorders. Oxford: Oxford Press; 2008. (in preparation).
Ondo WG. Restless legs syndrome: Diagnosis and treatment. Neurological disease and therapy ; v. 86. New York: Informa healthcare; 2007.
Ondo WG, editor. Restless legs syndrome. New York: Informa Healthcare; 2006.

Book Chapters
Collapse All | Expand All

Ondo WG. Secondary RLS. In: Chaudhuri R, editor. Restless legs syndrome handbook. Oxford: Oxford University Press; 2008. (in press).
Ondo WG. Pathophysiology, associations, and consequences of sleep related movement disorders. In: Kushida CA, editor. Hanbook of sleep disorders. 2nd ed. New York: Informa Health Care; 2008.
Ondo WG. Restless legs syndrome in Parkinson's disease. In: Chaudhuri R, Tolosa E, Schapira A, Poewe W, editors. Non-motor symptom complex of Parkinson's disease. Oxford: Oxford University Press; 2008. (in press).
Ondo WG, Zhao HR, Le WD. Animal models of restless legs syndrome. In: Chokroverty S, McCarley R, editors. Clinical neuroscience research: advances in sleep medicine. 2008. (in press).
Rodriguez R, Eisenschenk S, Fernandez H, Ondo W, Okun M. Epilepsia partialis continua presenting to a movement disorders clinic. In: Reich S, editor. Movement disorder case studies. 2007.
Satija P, Ondo WG. Cranial dystonia. In: Stacy M, editor. Handbook of dystonia. New York: Informa Healthcare; 2007.
Lalani I, Ondo WG. Other RLS associations. In: Ondo WG, editor. Restless legs syndrome. New York: Informa Healthcare; 2006.
Ondo WG. Future directions. In: Ondo WG, editor. Restless legs syndrome. New York: Informa Healthcare; 2006.
Ondo WG. Systemic iron deficiency. In: Ondo WG, editor. Restless legs syndrome. New York: Informa Healthcare; 2006.
Ondo WG. Treatment overview. In: Ondo WG, editor. Restless legs syndrome. New York: Informa Healthcare; 2006.
Ondo WG. Restless legs syndrome. In: Jankovic J, Tolosa E, editors. Parkinson's disease and movement disorders. 5th ed. Baltimore: William & Wilkins; 2006. p. 356-375.
Ondo WG. Investigational pharmacological treatments for Parkinson's disease. In: Pahwa R, editor. Handbook of Parkinson's disease. 4th ed. New York: Informa Healthcare; 2006.
Ondo WG. Essential tremor: treatment options. In: Weiner W, editor. Current treatment options in neurology. Vol. 8(3). Philadelphia: Heidelberg; 2006. p. 256-267.
Ondo WG. Restless legs syndrome and periodic limb movements of sleep. In: Fayle R, editor. Neurologic clinics: sleep medicine. Philadelphia: Elsevier; 2005. p. 1165-1186.
Ondo WG. Restless legs syndrome. In: Sethi K, editor. Current neurology and neuroscience reports. Vol. 5(4). Philadelphia: Heidelberg; 2005. p. 266-274.
Ondo WG, Polydefkis M. Restless legs syndrome in neurological disorders. In: Earley CJ, editor. Restless legs syndrome. 1st ed. Philadelphia: Elsevier; 2005.
Ondo WG. Secondary RLS. In: Chaudhuri R, Odin P, Olanow CW, editors. Restless legs syndrome. London: Taylor & Francis; 2004. p. 57-84.
Ondo WG, Krauss J. The surgical management of dystonia. In: Brin MF, Comella C, Jankovic J, editors. Dystonia: etiology, clinical features, and treatment. Philadelphia: Lippincott Williams & Wilkins; 2004. p. 125-150.
Ondo WG. Gait and balance disorders. In: Evans R, editor. The medical clinics of North America. Philadelphia: WB Saunders; 2003. p. 793-801.
Ondo WG. Transient Global amnesia and other amnesia disorders. In: Evans R, editor. Saunders manual of neurologic practice. Philadelphia: WB Saunders; 2003. p. 200-205.
Ondo WG. Treatment of restless legs syndrome. In: Chokroverty S, Hening W, Walters A, editors. Sleep and movement disorders. Philadelphia: Butterworth Heinemann; 2003. p. 348-361.
Ondo WG. Investigational pharmacological treatments for Parkinson's disease. In: Pahwa R, editor. Handbook of Parkinson's disease. 3rd ed. New York: Marcel Dekker; 2003. p. 453-461.
Ondo WG. Gait, balance and falls. In: Evans R, editor. Saunders manual of neurologic practice. Philadelphia: WB Saunders; 2003. p. 39-44.
Sanghera M, Grossman R, Kalhorn C, Hamilton W, Ondo W, Jankovic J. Basal ganglia neuronal discharges in primary and secondary dystonia. In: Fahn S, Hallett M, Delong M, editors. Advances in neurology: dystonia. Philadelphia: Lippincott, Williams & Wilkins; 2003. p. 29-36.
Jankovic J, Lai EC, Ondo WG, Roberts-Warrior D, Olson S, Krauss JK, Grossman R. Effects of pallidotomy on gait and balance. In: Ruzicka E, Hallett M, Jankovic J, editors. Gait disorders: advances in neurology. Philadelphia: Williams & Wilkins; 2001. p. 271-281.
Ondo WG, Desaloms JM. Pallidotomy and thalamotomy for treatment of dystonia. In: Krauss JK, Jankovic J, Grossman RG, editors. Surgery for Parkinson's disease and movement disorders. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 299-306.
Simpson R, Krauss J, Ondo WG. Thalamic stimulation for treatment of Parkinson's disease and tremor. In: Krauss J, Jankovic J, Grossman R, editors. Surgery for Parkinson's disease and movement disorders. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 154-160.
Yosher D, Hamilton W, Desaloms JM, Ondo WG, Jankovic J, Grossman R. Stereotactic neurosurgery for dystonia. In: Lozano A, editor. Movement disorder surgery: progress in neurological surgery. Basel: Karger; 2000. p. 279-295.
Ondo WG, Jankovic J. Pallidotomy and thalamotomy for treatment of dystonia. In: Krauss J, Jankovic J, Grossman R, editors. Parkinson's disease. New York: Lippincott-Raven; 1998. p. 67-100.
Ondo WG, Jankovic J. Restless legs syndrome. In: Appel S, editor. Current neurology. Chicago: Year Book Publishing; 1997. p. 207-236.

Poster Presentations
View Details | Collapse All | Expand All

Chaudhuri KR, Martinez-Martin P, Sherman R, Naidu Y, Odin P, Sethi K, Ondo W, Stocchi F, Schapira A, PD Non Motor Group. The non motor staging of Parkinson's disease: Results from an international study. Neurology. 2009;72(11 Suppl 3):A322.
Ferrara JM, Adam OR, Ondo WG. Levodopa-induced dyskinesias in spinocerebellar ataxia type 2. Neurology. 2009;72(11 Suppl 3):A346.
Moore ST, Shinawi L, Ondo WG. Gait analysis is more sensitive than finger tapping or UPDRS motor scores in assessment of the motor response to levodopa in Parkinson's disease. Mov Disord. 2009;24 Suppl 1:S269-70.
Ondo WG. Intravenous iron dextran for severe refractory restless legs syndrome. Mov Disord. 2009;24 Suppl 1:S444-5.
Ondo WG, Satija P, Ummat M. Task specific writing tremor: Series and outcomes. Mov Disord. 2009;24 Suppl 1:S511.
Aguilar Tabora LG, Davidson A, Jankovic J, Ondo WG. Characteristics of archimedean spiral drawing in patients with psychogenic tremor. Neurology. 2008;70(11 Suppl 1):A390-1.
Aguilar Tabora LG, Ondo WG. Exploring the relationship between drug-induced parkinsonism and tardive dyskinesias. Mov Disord. 2008;23 Suppl 1:S275.
Elble R, Comella C, Fahn S, Hallett M, Jankovic J, Juncos J, Louis E, Lyons K, Ondo WG, Pahwa R, Sethi K, Stern M, Tanner C, Tarsy D, Tintner R, Watts R, Tremor Research Group. The essential tremor rating assessment scale (TETRAS). Mov Disord. 2008;23 Suppl 1:S357.
Ferrara J, Ondo WG. Factors predicting adverse effects to subcutaneous apomorphine. Mov Disord. 2008;23 Suppl 1:S308-9.
Hening WA, Allen R, Becker PM, Bogan RK, Fry JM, Keffel J, Kudrow DB, Lesh KW, Ondo WG, Schollmayer E, Vrooman P, Walters A, Winkelman JW. Rotigotine 24h transdermal patch is effective in the treatment of idiopathic RLS: Results of a 6-month, multicenter, double-blind, placebo-controlled US trial. Mov Disord. 2008;23 Suppl 1:S366.
Lou FF, Zhu W, Xie W, Ondo W, Le W. Short-term and long-term improvement by pramipexole in restless leg syndrome animal model. Ann Neurol. 2008;64 Suppl 12:S54.
Moore ST, MacDougall HG, Ondo WG. Ambulatory monitoring of motor fluctuations and freezing of gait: Objective assessment of the efficacy of pharmacological treatments in Parkinson's disease. Mov Disord. 2008;23 Suppl 1:S216.
Ondo WG, Hunter CB, Davidson A, Isaacson SH, Silver DE, Stewart RM, Tetrud JW. Tolerability and efficacy of switching from swallowed selegiline to zydis selegiline (Zelapar®) in patients with Parkinson's disease. Mov Disord. 2008;23 Suppl 1:S222.
Ondo WG, Shinawi L, Davidson A. Memantine (Namenda®) for non-motor features of Parkinson's disease: A double blind placebo controlled trial. Mov Disord. 2008;23 Suppl 1:S254.
Ondo WG, Shinawi LM, Moore S. A single dose, placebo controlled, cross-over trial comparing the latency to onset of orally disintegrating (OD) levodopa (Parcopa) versus oral (PO) levodopa. Neurology. 2008;70(11 Suppl 1):A389.
Sitburana O, Ondo WG. Botulinum toxin A in electrical injury-induced cervical myoclonus. Mov Disord. 2008;23 Suppl 1:S190.
Walters AS, Ondo W, Zhu W, Le WD. Thalamic endogenous opioids are decreased in restless legs syndrome: A post-mortem study. Ann Neurol. 2008;64 Suppl 12:S29-30.
Moore ST, MacDougall HG, Ondo WG. Ambulatory monitoring of freezing of gait in Parkinson's disease. Mov Disord. 2007:22 Suppl 16:S78-8.
Panisset M, Schwid S, Ondo W, Fitzer-Attas C, Chen JJ. Safety of concomitant therapy with rasagiline and antidepressants in Parkinson's disease. Mov Disord. 2007:22 Suppl 16:S104-5.
Sitburana O, Almaguer M, Ondo W. Microlesion effects and tremor outcomes in ventrointermediate deep brain stimulation. Mov Disord. 2007:22 Suppl 16:S66.
Sitburana O, Rountree S, Vuong KD, Ondo W. Weight change in parkinson and alzheimer patients taking atypical antipsychotic drugs. Mov Disord. 2007:22 Suppl 16:S190.
Tanner C, Kukrull W, Shults C, Comyns K, Bhudhikanok G, May S, Goldman S, Meng C, Gilman S, Chade A, Kasten M, Colcher A, Huang N, Jankovic J, Low P, Marshall F, Novak P, Ondo W, Racette B, Reich S, Sandroni P, Stern M, Wooten GF. Head injury with amnesia and risk of multiple system atrophy (MSA). Neurology. 2007;68(12 Suppl 1):A49-50.
Bertoni JM, Arlette JP, Fernandez HH, Frei K, Gordon MF, Hassan MN, Isaacson SH, Lew MF, Molho E, Ondo WG, Phillips TJ, Singer C, Sutton JP, Wolf Jr JE. Epidemiologic association of Parkinson's disease and melanoma. Mov Disord. 2006;21 Suppl 15:S610.
Chaudhuri KR, Martinez-Martin P, Schapira AHV, Sethi K, Ondo W, Stocchi F, Odin P, Brown R, the International PD Non Motor Group (PDNMG). International validation of the first unified Non Motor Symptoms Scale for Parkinson's disease. Results from the first pilot NMSS study. Neurology. 2006;66(5 Suppl 2):A124.
Clayton LM, Naidu Y, Odin P, Martinez P, Sethi K, Schapira A, Bonuccelli U, Stocchi F, Rabey M, MacMahon D, MacPhee G, Forbes A, Ondo W, Tsubio Y, Chaudhuri KR. Comparison of the prevalence and pattern of non-motor symptoms in Parkinson's disease in drug naive and treated patients using the NMSQuest. Mov Disord. 2006;21 Suppl 15:S648.
Kenney C, Simpson Jr RK, Hunter CB, Ondo WG, Almaguer M, Davidson A, Jankovic J. Short-term and long-term safety of deep brain stimulation in the treatment of movement disorders. Neurology. 2006;66(5 Suppl 2):A49-50.
Moore S, MacDougall H, Gracies J, Ondo W. Assessment of locomotor response to levodopa in fluctuating Parkinson's disease. Mov Disord. 2006;21 Suppl 15:S462-3.
Moore ST, MacDougall HG, Cohen HS, Ondo WG. Continuous assessment of gait via stride monitoring: a new approach to management of locomotor dysfunction in Parkinson's disease. Neurology. 2006;66(5 Suppl 2):A314.
Naidu Y, Schapira AH, Martinez-Martin P, Sethi K, Odin P, Stocchi F, Ondo W, Olanow CW, Barone P, MacMahon D, MacPhee G, Forbes A, Rabey M, Breen K, Bowron A, Tluk S, Thomas S, Abe K, Williams A, Rye D, Chaudhuri KR. International validation study of the first comprehensive unified nonmotor symptoms scale (NMSS) for Parkinson's disease (PD). Mov Disord. 2006;21 Suppl 15:S613.
Ondo WG, Jong D, Davidson A. Comparison of weight gain in treatments for Tourette's syndrome: Tetrabenazine versus neuroleptics. Mov Disord. 2006;21 Suppl 15:S695.
Ondo WG, Khan F. Zonisamide for essential tremor. Mov Disord. 2006;21 Suppl 15:S705.
Ondo WG, Lai D. Predictors of impulsivity and reward seeking behavior with dopamine agonists. Mov Disord. 2006;21 Suppl 15:S582-3.
Ondo WG, Perkins T, Swick T, Hull, Jr. KL, Jimenez JE, Pardi D. Sodium oxybate for excessive daytime sleepiness in Parkinson's disease: A polysomnographic study. Mov Disord. 2006;21 Suppl 15:S512.
Ondo WG, Satija P. Withdrawal of visual feedback improves micrographia in Parkinson's disease. Mov Disord. 2006;21 Suppl 15:S485.
Sitburana O, Ondo WG. Weight change in Parkinson's disease patients taking atypical antipsychotics. Ann Neurol. 2006;60 Suppl 10:S81.
Sitburana O, Ondo WG. Weight change in Parkinson's disease patients taking atypical antipsychotics. Neurology. 2006;66(5 Suppl 2):A49.
Sitburana O, Ondo WG. Tetrabenazine for hyperglcemic-induced hemichorea-hemiballismus. Mov Disord. 2006;21 Suppl 15:S353-4.
Zhao H, Zhu W, Pan T, Xie W, Ondo W, Le W. Spinal cord dopamine receptor expression and function in mice with 6-OHDA lesion of the A11 nucleus and dietary iron deprivation. Mov Disord. 2006;21 Suppl 15:S341.
Chaudhuri KR, Martinez-Martin P, Schapira AHV, Ondo W, Sethi K, Members of The PD NMS Scale Development Group. An international multicentre study validating the first screening questionnaire (NMS-quest) for comprehensive assessment of non motor symptoms of Parkinson's disease. Mov Disord. 2005:20 Suppl 10:S50.
Hauser R, Lew M, Hurtig H, Ondo W, Wojcieszek J. Early treatment with rasagiline is more beneficial than delayed treatment start in the long-term management of Parkinson's disease. Neurology. 2005;64(6 Suppl 1):A107.
Lew M, Hauser R, Hurtig H, Ondo W, Wojcieszek J. Long-term efficacy of rasagiline in Parkinson's disease. Neurology. 2005;64(6 Suppl 1):A396.
Mejia NI, Hunter C, Flores K, Ondo WG. A pilot study of the clinical efficacy and safety of memantine for Huntington's disease. Mov Disord. 2005:20 Suppl 10:S10-1.
Ondo WG, Haykal HA. Paraspinal muscle asymmetry in Parkinson's disease. Mov Disord. 2005:20 Suppl 10:S130.
Ondo WG, Lai D. The association between restless legs syndrome and essential tremor. Mov Disord. 2005:20 Suppl 10:S171.
Ondo WG, Meilak C, Vuong KD, Jankovic J. Predictors of battery life for the Activa® Soletra 7426 neurostimulator. Mov Disord. 2005:20 Suppl 10:S160-1.
Ondo WG, Silay Y, Almaguer M, Jankovic J. Subthalamic deep brain stimulation in patients with a previous pallidotomy. Mov Disord. 2005:20 Suppl 10:S163.
Chen S, Ondo WG, Rao S, Li L, Wang Q. Genome-wide model-based and model-free linkage analyses co-localize a novel genetic locus on chromosome 9p for familial restless legs syndrome. Neurology. 2004:62(7 Suppl S5):A4-5.
Jankovic J, Ondo WG, Stacy MA, Elble RJ, Pahwa R, Connor GS, Hulihan FJ, Schwarzman L, Wu SC. A multicenter, double-blind, placebo-controlled trial of topiramate in essential tremor. Mov Disord. 2004:19 Suppl 9:S448-9.
Ondo WG, Bronte-Stewart H for the DBS Study Group. The north American survey of placement and adjustment strategies for deep brain stimulation. Neurology. 2004:62(7 Suppl S5):A393.
Silay Y, Jankovic J, Vuong KD, Almageur M, Ondo WG, Tintner R, Simpson Jr RK. The safety of deep brain stimulation in patients with Parkinson's disease, essential tremor, and other movement disorders. Ann Neurol. 2004;56 Suppl 8:S54-5.
Kuniyoshi S, Tintner R, Ondo W, Simpson R, Jankovic J. Comparison of postoperative improvement of staged bilateral subthalamic stimulation in patients with advanced Parkinson's disease. Neurology. 2003;60(5 Suppl 1):A120.
Ondo WG, Hunter CB, Moore W. A double blind placebo controlled parallel trial of botulinum toxin B (Myobloc™) for the treatment of sialorrhea in parkinson disease. Neurology. 2003;60(5 Suppl 1):A47-8.
Ondo WG, Romanyshyn J, Vuong KD. Long term treatment of restless legs syndrome with dopamine agonists. Neurology. 2003;60(5 Suppl 1):A291.
Ondo WG, Cohen H, Almaguer M, Jankovic J. Computerized posturography balance assessment of patients with bilateral vim deep brain stimulation. Mov Disord. 2002:17 Suppl 5:S190-1.
Ondo WG, Vuong KD, Derman HS. Botulinum toxin A (Botox) for chronic daily headache: A randomized placebo-controlled, parallel design study. Headache. 2002;42(5):414.
Ondo WG, Wang A, Thomas M, Vuong KD. Evaluating factors that can influence spirography ratings in patients with essential tremor. Mov Disord. 2002:17 Suppl 5:S344.
Tintner R, Almaguer M, Sanghera M, Simpson R, Ondo WG, Jankovic J. Experience with bilateral subthalamic nucleus (STN) stimulation for Parkinson's disease (PD). Mov Disord. 2002:17 Suppl 5:S196.
Tintner R, Almaguer M, Vuong KD, Ondo WG, Jankovic J, Sanghera M. Predictors of response to bilateral subthalamic nucleus stimulation for Parkinson's disease. Mov Disord. 2002:17 Suppl 5:S208.
Atassi F, Vuong KD, Jankovic J, Ondo WG. The prevalence of restless legs syndrome in patients with Parkinson's disease. Neurology. 2001;56(8 Suppl 3):A21.
Ondo WG, Vuong KD, Jankovic J. Exploring the relationship between Parkinson's disease and restless legs syndrome. Neurology. 2001;56(8 Suppl 3).
Ondo WG, Hunter C, Vuong KD, Jankovic J. Olanzapine treatment for dopaminergic induced hallucinations. Movement Disorder Society (MDS), 6th International Congress of Parkinson's Disease and Movement Disorders in Barcelona, Spain (June 11-15, 2000).
Ondo WG, Vuong KD, Atassi F, Khan H, Kwak C, Jankovic J. Daytime sleepiness in patients with Parkinson's disease. Movement Disorder Society (MDS), 6th International Congress of Parkinson's Disease and Movement Disorders in Barcelona, Spain (June 11-15, 2000).
Vuong KD, Ondo WnG, Almaguer M, Simpson RK, Jankovic J. Unilateral thalamic deep brain stimulation for essential tremor and Parkinson's disease: Effects of stimulation on the non-target limb and rebound augmentation. Neurology. 2000;54(Suppl 3):A54.

Contact Information

William G. Ondo, M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Tel: 713-798-7438
Fax: 713-798-6808
Email: