Hui-Chen Lu, Ph.D.
Assistant Professor of Pediatrics-Neurology
Graduate School
Ph.D., Baylor College of Medicine, Houston, TX
Research Interests
Molecular mechanisms of cortical map development. Exploration of the activity-dependent processes affecting cortical map development and plasticity using the mouse barrel map as a model system. The study of mouse mutants with barrel map deficits, including barrelless mice (the null mutant mice of calcium-activated adenylyl cyclase I, AC1), the loss-of-function mutant mice of mGluR5 (metabotropic glutamate receptor) and PKARIIß (protein kinase A regulatory subunit II ß subunit). The role of cAMP in activity-dependent processes regulating precise whisker-to-barrel connections. The role of cAMP/PKA signaling cascades in cortical map development. Employment of electrophysiological, pharmacological, anatomical, and biochemical techniques in elucidating cortical map development and plasticity.
Contact Information
Hui-Chen Lu, Ph.D.
Feigin Center, Suite 955
1102 Bates Street
Houston, Texas 77030
Tel: 832-824-3966
Fax: 832-825-4217
Email: