George J. Hutton, M.D.

Associate Professor of Neurology

Clinical Service Area

Neurology

Specialty

Demyelinating Diseases
General Neurology
Optic Neuritis
Multiple Sclerosis

Board Certification

American Board of Psychiatry and Neurology, Neurology

Clinic Appointments

713-798-8170

Consult

713-798-8170

Medical School

M.D., Vanderbilt University School of Medicine, Nashville, TN

Internship

Internal Medicine, Baylor College of Medicine, Houston, TX

Residency

Neurology, Baylor College of Medicine, Houston, TX

Fellowship

Multiple Sclerosis, Baylor College of Medicine, Houston, TX

Clinical Interests

Multiple sclerosis and other demyelinating diseases of the central nervous system (adult and pediatric), Neurologic complications of pregnancy, Neurologic complications after bone marrow transplantation

Clinic Location

Maxine Mesinger MS Comprehensive Care Center
Neurosensory Building
6501 Fannin, NB100
Houston, Texas 77030

Journal Publications
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Cohen JA, Imrey PB, Calabresi PA, Edwards KR, Eickenhorst T, Felton WL, 3rd, Fisher E, Fox RJ, Goodman AD, Hara-Cleaver C, Hutton GJ, Mandell BF, Scott TF, Zhang H, Apperson-Hansen C, Beck GJ, Houghtaling PL, Karafa MT, Stadtler M. Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS. Neurology. 2009;72:535-541.

Hutton GJ, Avila M, Suarez GA. Pneumocephalus after an epidural steroid injection. Clin Neurol Neurosurg. 2009;111:309-10.

Brodsky M, Orengo-Nania S, Hutton GJ, Slight B, Buckley EG, Massey EW, Anderson MM, Duncan LB, Bhatti MT, Greer M, Burke R, Preston R, Goodwin J, Cross A, Garcia-Ovando Y, Wall M, Musser C, Carney B, Longmuir R, Randhawa S, et al. Visual function 15 years after optic neuritis: a final follow-up report from the Optic Neuritis Treatment Trial. Ophthalmology. 2008;115:1079-1082 e5.

Cohen JA, Calabresi PA, Chakraborty S, Edwards KR, Eickenhorst T, Felton WL, 3rd, Fisher E, Fox RJ, Goodman AD, Hara-Cleaver C, Hutton GJ, Imrey PB, Ivancic DM, Mandell BF, Perryman JE, Scott TF, Skaramagas TT, Zhang H. Avonex Combination Trial in relapsing--remitting MS: rationale, design and baseline data. Mult Scler. 2008;14:370-82.

Coles AJ, Compston DA, Selmaj KW, Lake SL, Moran S, Margolin DH, Norris K, Tandon PK. Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N Engl J Med. 2008;359:1786-801.

Lotze TE, Northrop JL, Hutton GJ, Ross B, Schiffman JS, Hunter JV. Spectrum of pediatric neuromyelitis optica. Pediatrics. 2008;122:e1039-47.

Nash RA, Stuve O, Bowen JD, Frohman EM, Griffith LM, Hutton GJ, Kraft GH, Popat U, Racke MK, Muraro PA. Autologous HSCT for advanced MS: is the glass half-empty or really half-full? Brain. 2008;131:e89; author reply e90.

Suarez Zambrano GA, Hutton GJ. Heart-shaped lesion secondary to neurosarcoidosis. Arch Neurol. 2008;65:1388-9.

Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R. Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007;39:705-9.

Zhang J, Hutton G. Role of magnetic resonance imaging and immunotherapy in treating multiple sclerosis. Annu Rev Med. 2005;56:273-302.

Bakshi R, Hutton GJ, Miller JR, Radue EW. The use of magnetic resonance imaging in the diagnosis and long-term management of multiple sclerosis. Neurology. 2004;63:S3-11.

Hong J, Zang YC, Hutton G, Rivera VM, Zhang JZ. Gene expression profiling of relevant biomarkers for treatment evaluation in multiple sclerosis. J Neuroimmunol. 2004;152:126-39.

Rivera-Olmos VM, Hutton GJ, Breitbach WT. Discrepancia entre clínica e imagen: esclerosis múltiple en fase intermedia. Presentación de un caso y revisión del tema [Discrepancy between clinics and image techniques: intermediate phase of multiple sclerosis. A case report and review of the literature]. Rev Mex Neuroci. 2004;5:158-62.

Sun W, Popat U, Hutton G, Zang YC, Krance R, Carrum G, Land GA, Heslop H, Brenner M, Zhang JZ. Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis. Brain. 2004;127:996-1008.

Zang YC, Skinner SM, Robinson RR, Li S, Rivera VM, Hutton GJ, Zhang JZ. Regulation of differentiation and functional properties of monocytes and monocyte-derived dendritic cells by interferon beta in multiple sclerosis. Mult Scler. 2004;10:499-506.

Zhang J, Hutton G, Zang Y. A comparison of the mechanisms of action of interferon beta and glatiramer acetate in the treatment of multiple sclerosis. Clin Ther. 2002;24:1998-2021.

Book Chapters and Other Publications
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Zhang J, Hutton G. Therapeutic targets for the treatment of multiple sclerosis. In: Columbus F, editor. Treatment and management of multiple sclerosis. New York: Nova Biomedical Books; 2005. p. 107-153.

Hutton G, Oyama Y, Burt RK, Popat U. Hematopoietic stem cell transplantation in the treatment of chronic inflammatory demyelinating polyradiculoneuropathy. In: Burt RK, Marmont AM, editors. Stem cell therapy for autoimmune diseases. Georgetown (TX): Landes Bioscience; 2004. p. 419-428.

Hutton GJ. Demyelinating and inflammatory diseases of the central nervous system. In: Poolos N, editor. Handbook of differential diagnosis in neurology. Boston: Butterworth-Heinemann; 2001. p. 63-79.

Poster and Platform Presentations
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Avila M, Prieto PG, Robles L, Hutton GJ, Rivera VM. Clinical and radiographic improvement of an acutely aggressive case of multiple sclerosis treated with cyclophosphamide. Int J MS Care. 2009;11 Suppl 2:52-3.

Avila M, Robles L, Prieto P, Bernitsas E, Stosic M, Hutton GJ, Rivera VM. Prevalence of sleep disorders in multiple sclerosis. Int J MS Care. 2009;11 Suppl 2:83.

Bernitsas E, Hutton GJ, Rivera VM. Deep brain stimulation in multiple sclerosis-related Holmes' tremor. Ann Neurol. 2009;66 Suppl 13:S40.

Bernitsas E, Hutton GJ, Rivera VM. Spasmodic dysphonia in MS: A rare symptom or a possible association? Int J MS Care. 2009;11 Suppl 2:31-2.

Bernitsas E, Stosic M, Hutton GH, Rivera VM. Seizures in MS patients: A retrospective study. Int J MS Care. 2009;11 Suppl 2:32.

Helekar SA, Shin JC, Mattson BJ, Bartley K, Stosic M, Saldana-King T, Montague PR, Hutton GJ. Functional correlation of brain loci during cognitive tasks in multiple sclerosis. Program No. 244.25. 2009 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2009. Online.

Hutton GJ, Bowen J, Forman S, Frohman E, Griffith L, Kraft G, Muraro P, Openshaw H, Popat U, Racke M, Sayre P, Stuve O, Wundes A, Nash R. HALT-MS--Intense immunosuppression and stem cell transplantation for RRMS. Int J MS Care. 2009;11 Suppl 2:4.

Robles L, Prieto P, DeAlvare L, Hutton GJ, Rivera VM. Difusse white matter abnormalities and neurologic manifestations in a patient with anti-ro positive antibodies. Case Report.. Int J MS Care. 2009;11 Suppl 2:43.

Robles L, Prieto P, Rivera VM, Hutton GJ. Occurrence of herpes zoster in multiple sclerosis patients treated with natalizumab. Int J MS Care. 2009;11 Suppl 2:43.

Wundes A, Bowen J, Kraft G, Hutton G, Openshaw H, Forman S, Frohman E, Griffith L, Muraro P, Racke M, Sayre P, Stuve O, Popat U, Nash R. HALT MS – Phase II clinical trial of high dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation for active relapsing- remitting multiple sclerosis. Neurology. 2009;72(11 Suppl 3):A356.

Avila M, Suarez GA, Brandt D, Ramirez J, Hutton GJ, Rivera VM. Menstrual cycle and menopause in patients with multiple sclerosis. How do these affect the symptoms of disease? Mult Scler. 2008;14 Suppl 1:S155.

Bernitsas E, Hutton GJ, Rivera VM. Marburg's disease and neuromyelitis optica in brother/sister. National Multiple Sclerosis Society (NMSS), Tykeson Fellows Conference in Chicago, Illinois (Nov. 4-7, 2008).

Chaliman RT, Perez FI, Suarez GA, Rivera VM, Hutton GJ. Longitudinal individualized analysis of computer-based cognitive rehabilitation in multiple sclerosis. Mult Scler. 2008;14 Suppl 1:S152.

Cohen J, Imrey P, Calabresi P, Chakraborty S, Edwards K, Eickenhorst T, Felton W, Fisher E, Fox R, Goodman A, Hara-Cleaver C, Hutton G, Mandell B, Scott T, Zhang H for the ACT. Site performance in an investigator-run multiple sclerosis clinical trial. Neurology. 2008;70(11 Suppl 1):A84.

Kraft GH, Bowen JD, Openshaw H, Forman SJ, Frohman EM, Griffith LM, Hutton GJ, Muraro PA, Popat U, Racke MK, Sayre P, Stuve O, Wundes A, Nash RA. Phase II clinical trial (HALT-MS: Immune tolerance network) of high dose immunosuppressive therapy (HDIT) and autologus hematopoetic stem cell transplantation (AHSCT) for active relapsing-remitting (RR) multiple sclerosis (MS): Early results. Neurology. 2008;70(11 Suppl 1):A95.

Suarez GA, Avila M, Brandt D, Rivera VM, Hutton GJ. Magnetic resonance imaging findings in patients with clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2008;14 Suppl 1:S223.

Suarez-Zambrano GA, Pena JA, Avila M, Hutton GJ, Rivera VM. Frequency and severity of restless legs syndrome in multiple sclerosis: A population study from southeast Texas. Neurology. 2008;70(11 Suppl 1):A334.

Suarez-Zambrano GA, Ramirez J, Avila M, Brandt D, Escobar BH, Hutton GJ, Rivera VM. Silent MRI white matter lesions in patients with CIS suggestive of multiple sclerosis. Int J MS Care. 2008;10 Suppl 1:52.

Avila M, Ramirez J, Suarez-Zambrano GA, Hutton GJ, Rivera VM. Multiple sclerosis and antiphospholipid syndrome: Case report. Mexican Academy of Neurology, 31st Annual Meeting in Monterrey, Mexico (Oct. 31 - Nov. 5, 2007).

Avila M, Suarez-Zambrano GA, Ramirez J, Hutton GJ, Rivera VM. Encefalomielitis diseminada recurrente y multifásica reporte de 2 casos. Mexican Academy of Neurology, 31st Annual Meeting in Monterrey, Mexico (Oct. 31 - Nov. 5, 2007). [Recurrent Disseminated Encephalomyelitis: Report of 2 Cases]

Cohen J, Calabresi P, Eickenhorst T, Edwards K, Felton W, Fisher E, Fox R, Goodman A, Hara-Cleaver C, Hutton G, Imrey P, Mandell B, Scott T, Zhang H. Results of the Avonex Combination Trial (ACT). Neurology. 2007;68(12 Suppl 1):A100.

Hutton GJ, Avila M, Suarez-Zambrano GA, Ramirez J, Rivera VM. Recurrent disseminated encephalomyelitis: Report of 2 cases. European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), 23rd Congress in Prague, Czech Republic (Oct. 11-14, 2007).

Hutton GJ, Suarez-Zambrano GA, Jafree I, Landero S, Avila M, Rivera VM. Is restless legs syndrome more frequent and severe in the multiple sclerosis population? Study in multiple sclerosis patients from southeast Texas. European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), 23rd Congress in Prague, Czech Republic (Oct. 11-14, 2007).

Jafree I, Hashmi K, Landero S, Suarez G, Hutton GJ, Rivera VM. Multiple sclerosis and other autoimmune diseases. Int J MS Care. 2007;9(2):65.

Landero S, Rivera VM, Hutton GJ, Suarez-Zambrano GA, Ramirez J. Behavior of multiple sclerosis during pregnancy and after delivery. Int J MS Care. 2007;9(2):67.

Nash R, Openshaw H, Bowen JD, Forman SJ, Stuve O, Hutton GJ, Popat U, Wundes A, Kraft G. A phase II study of high-dose immunosuppressive therapy (HDIT) using carmustine, etoposide, cytarabine, and melphalan (beam) + thymoglobulin, and autologous CD34+ hematopoietic stem cell transplant (HCT) for the treatment of poor prognosis multiple sclerosis. HALT-MS. Int J MS Care. 2007;9(2):90.

Suarez-Zambrano GA, Avila M, Landero S, Jafree I, Escobar BH, Ramirez J, Brandt D, Hutton GJ, Rivera VM. Experiencia con natalizumab en 40 pacientes con esclerosis multiple exacerbacion remision. Colombian Academy of Neurology, VIII Meeting in Cali, Colombia (Aug. 16-19, 2007).

Suarez-Zambrano GA, Escobar BH, Avila M, Ramirez J, Hutton GJ, Rivera VM. Experience with natalizumab in a group of ms patients from southeast Texas. Mexican Academy of Neurology, 31st Annual Meeting in Monterrey, Mexico (Oct. 31 - Nov. 5, 2007).

Suarez-Zambrano GA, Landero S, Jafree I, Hutton GJ, Rivera VM. Frequency and severity of restless legs syndrome in ms patients from southeast Texas. Int J MS Care. 2007;9(2):77.

Suarez-Zambrano GA, Landero S, Jafree I, Hutton GJ, Rivera VM. Multiple sclerosis in African Americans: A cohort from southeast Texas. Int J MS Care. 2007;9(2):77-8.

Suarez-Zambrano GA, Perez F, Avila M, Hutton GJ, Rivera VM. Computer-assisted cognitive rehabilitation in patients with multiple sclerosis. Int J MS Care. 2007;9(2):93.

Cohen J, Calabresi P, Edwards K, Eickenhorst T, Felton W, Fisher E, Fox R, Goodman A, Hara-Cleaver C, Hutton G, Imrey P, Mandell B, Scott T, Zhang H. Rationale, design, and baseline data for the Avonex Combination Trial (ACT). Neurology. 2006;66(5 Suppl 2):A32-3.

Suarez-Zambrano GA, Perez F, Avila M, Hutton GJ, Rivera VM. Rehabilitación cognitiva asistida por computadora en pacientes con esclerosis múltiple. Rev Mex Neuroci. 2006;7(5):504.

Contact Information

George J. Hutton, M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Tel: 713-798-8170
Fax: 713-798-0115
Email: