Richard A. Hrachovy, M.D.

Professor of Neurology

Clinical Service Area

Neurology

Specialty

Epilepsy
Clinical Neurophysiology

Board Certification

American Board of Psychiatry and Neurology, Neurology
American Board of Psychiatry and Neurology, Clinical Neurophysiology

Clinic Appointments

713-798-0980

Consult

713-798-0980

Medical School

University of Texas Medical Branch, Galveston, TX

Residency

Neurology, University of Texas Medical Branch, Galveston, TX

Fellowship

Neurophysiology, Baylor College of Medicine, Houston, TX

Clinical Interests

Clinical neurophysiology, electroencephalography, epilepsy, neonatal seizures, infantile spasms

Clinic Location

Baylor Neurophysiology

6565 Fannin, MS 587
Houston, TX 77030

Publications

Guggenheim MA, Frost JD, Jr., Hrachovy RA. Time interval from a brain insult to the onset of infantile spasms. Pediatr Neurol 2008;38:34-7.
Lee CL, Frost JD, Jr., Swann JW, Hrachovy RA. A new animal model of infantile spasms with unprovoked persistent seizures. Epilepsia 2008;49:298-307.
Guerra MP, Hrachovy RA, Lugli L, Mizrahi EM, Ferrari F. A new lethal case of joint contractures, facial abnormalities, pachygyria plus early-onset encephalopathy with a suppression-burst EEG pattern. Eur J Paediatr Neurol 2007;11:318-321.
Kawai M, Hrachovy RA, Franklin PJ, Foreman PJ. Video-EEG monitoring in a geriatric veteran population. J Clin Neurophysiol 2007;24:429-32.
Lee CL, Frost JD, Jr., Swann JW, Hrachovy RA. A new animal model of infantile spasms with unprovoked persistent seizures. Epilepsia 2007;:.
Hrachovy RA, Frost JD, Jr.. The EEG in selected generalized seizures. J Clin Neurophysiol 2006;23:312-32.
Karayiannis NB, Mukherjee A, Glover JR, Ktonas PY, Frost JD, Jr., Hrachovy RA, Mizrahi EM. Detection of pseudosinusoidal epileptic seizure segments in the neonatal EEG by cascading a rule-based algorithm with a neural network. IEEE Trans Biomed Eng 2006;53:633-41.
Karayiannis NB, Tao G, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures based on motion segmentation methods. Clin Neurophysiol 2006;117:1585-94.
Karayiannis NB, Xiong Y, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures based on motion tracking methods. J Clin Neurophysiol 2006;23:521-31.
Karayiannis NB, Xiong Y, Tao G, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures of epileptic origin. Epilepsia 2006;47:966-80.
Frost JD, Jr., Hrachovy RA. Pathogenesis of infantile spasms: a model based on developmental desynchronization. J Clin Neurophysiol 2005;22:25-36.
Mitra J, Glover J, Ktonas P, Frost J, Hrachovy R, Mizrahi E. Rule-enhanced Clustering in the Detection of Neonatal Seizures. Conf Proc IEEE Eng Med Biol Soc 2005;1:948-51.
Karayiannis NB, Mukherjee A, Glover JR, Ktonas PY, Frost JD, Jr., Hrachovy RA, Mizrahi EM. Quantifying and visualizing uncertainty in EEG data of neonatal seizures. Conf Proc IEEE Eng Med Biol Soc 2004;1:423-6.
Mitra J, Glover JR, Frost JD, Ktonas PA, Hrachovy RA, Mizrahi EM. Enhanced spatio-temporal clustering in the detection of neonatal seizures using context-based rules. Conf Proc IEEE Eng Med Biol Soc 2004;7:4717-20.
Hrachovy RA, Frost JD, Jr.. Infantile epileptic encephalopathy with hypsarrhythmia (infantile spasms/West syndrome). J Clin Neurophysiol 2003;20:408-25.
Hrachovy RA. West's syndrome (infantile spasms). Clinical description and diagnosis. Adv Exp Med Biol 2002;497:33-50.
Lee CL, Hannay J, Hrachovy R, Rashid S, Antalffy B, Swann JW. Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy. Neuroscience 2001;107:71-84.
Galvan CD, Hrachovy RA, Smith KL, Swann JW. Blockade of neuronal activity during hippocampal development produces a chronic focal epilepsy in the rat. J Neurosci 2000;20:2904-16.
Swann JW, Lee CL, Smith KL, Hrachovy RA. Developmental neuroplasticity and epilepsy. Epilepsia 2000;41:1078-9.
Anderson AE, Hrachovy RA, Antalffy BA, Armstrong DL, Swann JW. A chronic focal epilepsy with mossy fiber sprouting follows recurrent seizures induced by intrahippocampal tetanus toxin injection in infant rats. Neuroscience 1999;92:73-82.
Hrachovy RA, O'Donnell DM. The significance of excessive rhythmic alpha and/or theta frequency activity in the EEG of the neonate. Clin Neurophysiol 1999;110:438-44.
Rashid S, Lee I, Anderson AE, Hrachovy RA, Swann JW. Insights into the tetanus toxin model of early-onset epilepsy from long-term video monitoring during anticonvulsant therapy. Brain Res Dev Brain Res 1999;118:221-5.
Anderson AE, Hrachovy RA, Swann JW. Increased susceptibility to tetanus toxin-induced seizures in immature rats. Epilepsy Res 1997;26:433-42.
Frost JD, Jr., Hrachovy RA, Glaze DG, Rettig GM. Alpha rhythm slowing during initiation of carbamazepine therapy: implications for future cognitive performance. J Clin Neurophysiol 1995;12:57-63.
Lee CL, Hrachovy RA, Smith KL, Frost JD, Jr., Swann JW. Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood. Brain Res 1995;677:97-109.
Hrachovy RA, Frost JD, Jr., Glaze DG. Coupling of focal electrical seizure discharges with infantile spasms: incidence during long-term monitoring in newly diagnosed patients. J Clin Neurophysiol 1994;11:461-4.
Hrachovy RA, Frost JD, Jr., Glaze DG. High-dose, long-duration versus low-dose, short-duration corticotropin therapy for infantile spasms. J Pediatr 1994;124:803-6.
Frost JD, Jr., Hrachovy RA, Glaze DG. Spike morphology in childhood focal epilepsy: relationship to syndromic classification. Epilepsia 1992;33:531-6.
Smith Doody R, Hrachovy RA, Feher EP. Recurrent fluent aphasia associated with a seizure focus. Brain Lang 1992;42:419-30.
Frost JD, Jr., Hrachovy RA, Glaze DG, McCully MI. Sleep modulation of interictal spike configuration in untreated children with partial seizures. Epilepsia 1991;32:341-6.
Hrachovy RA, Frost JD, Jr., Glaze DG, Kellaway P. Surgical treatment for infantile spasms?. Ann Neurol 1991;29:110-2.
Hrachovy RA, Glaze DG, Frost JD, Jr.. A retrospective study of spontaneous remission and long-term outcome in patients with infantile spasms. Epilepsia 1991;32:212-4.
Hrachovy RA, Frost JD, Jr.. Infantile spasms. Cleve Clin J Med 1989;:S10-6; dicussion S40-2.
Hrachovy RA, Frost JD, Jr.. Infantile spasms. Pediatr Clin North Am 1989;36:311-29.
Hrachovy RA, Frost JD, Jr., Glaze DG, Rose D. Treatment of infantile spasms with methysergide and alpha-methylparatyrosine. Epilepsia 1989;30:607-10.
Glaze DG, Hrachovy RA, Frost JD, Jr., Kellaway P, Zion TE. Prospective study of outcome of infants with infantile spasms treated during controlled studies of ACTH and prednisone. J Pediatr 1988;112:389-96.
Hrachovy RA, Frost JD, Jr., Glaze DG. Treatment of infantile spasms with tetrabenazine. Epilepsia 1988;29:561-3.
Hrachovy RA, Frost JD, Jr., Pollack MS, Glaze DG. Serologic HLA typing in infantile spasms. Epilepsia 1988;29:817-9.
Hrachovy RA, Frost JD, Jr., Gospe SM, Jr., Glaze DG. Infantile spasms following near-drowning: a report of two cases. Epilepsia 1987;28:45-8.
Frost JD, Jr., Kellaway P, Hrachovy RA, Glaze DG, Mizrahi EM. Changes in epileptic spike configuration associated with attainment of seizure control. Ann Neurol 1986;20:723-6.
Glaze DG, Hrachovy RA, Frost JD, Jr., Zion TE, Bryan RN. Computed tomography in infantile spasms: effects of hormonal therapy. Pediatr Neurol 1986;2:23-7.
Hrachovy RA, Frost JD, Jr., Glaze DG. What have we learned about sudden infant death?. N Engl J Med 1984;310:787-8.
Hrachovy RA, Frost JD, Jr., Kellaway P. Hypsarrhythmia: variations on the theme. Epilepsia 1984;25:317-25.
Strickbine-Van Reet P, Glaze DG, Hrachovy RA. A preliminary prospective neurophysiological study of coma in children. Am J Dis Child 1984;138:492-5.
Hrachovy RA, Frost JD, Jr., Kellaway P, Zion TE. Double-blind study of ACTH vs prednisone therapy in infantile spasms. J Pediatr 1983;103:641-5.
Kellaway P, Hrachovy RA. Status epilepticus in newborns: a perspective on neonatal seizures. Adv Neurol 1983;34:93-9.
Hrachovy RA. Drug-induced alpha coma. Neurology 1982;32:1319.
Hrachovy RA, Frost JD, Jr., Kellaway P. Sleep characteristics in infantile spasms. Neurology 1981;31:688-93.
Hrachovy RA, Frost JD, Jr., Kellaway P, Zion T. A controlled study of ACTH therapy in infantile spasms. Epilepsia 1980;21:631-6.
Hrachovy RA, Frost JD, Jr., Kellaway P, Zion T. A controlled study of prednisone therapy in infantile spasms. Epilepsia 1979;20:403-7.
Kellaway P, Hrachovy RA, Frost JD, Jr., Zion T. Precise characterization and quantification of infantile spasms. Ann Neurol 1979;6:214-8.
Frost JD, Jr., Hrachovy RA, Kellaway P, Zion T. Quantitative analysis and characterization of infantile spasms. Epilepsia 1978;19:273-82.
Bruhn JG, Hrachovy RA. Black college students' attitudes toward opportunities in the health professions. J Med Educ 1977;52:847-9.

Contact Information

Richard A. Hrachovy, M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Tel: 713-798-0980
Fax: 713-798-0984
Email: