Yadollah Harati, M.D.

Professor of Neurology

Clinical Service Area

Neurology

Specialty

Neuromuscular Diseases

Board Certification

American Board of Psychiatry and Neurology, Neurology

Clinic Appointments

713-798-7411

Consult

713-798-7411

Medical School

University of Tehran, Tehran, Iran

Internship

St. Vincent Charity Hospital, Cleveland, OH

Residency

Neurology, University of Nebraska College Medical, Omaha, NE
Neurology, Baylor College of Medicine, Houston, TX

Fellowship

Neuromuscular Diseases, Baylor College of Medicine, Houston, TX

Clinical Interests

Neuromuscular disorders, nerve and muscle pathology, peripheral neuropathies (diabetes, immune-mediated, toxic), amyotrophic lateral sclerosis, inflammatory myopathies and myasthenia gravis, disorders of autonomic nervous system, muscular dystrophies

Clinic Location

Baylor Neurology
Smith Tower
6550 Fannin, Suite 1801
Houston, TX 77030

Research Interests

Neuromuscular therapy, peripheral neuropathies, ALS, neuromuscular pathology, myasthenia gravis

Publications

Harati Y. Diabetic neuropathies: unanswered questions. Neurol Clin 2007;25:303-17.
Murtagh B, Wadia Y, Messner G, Allison P, Harati Y, Delgado R. West Nile virus infection after cardiac transplantation. J Heart Lung Transplant 2005;24:774-6.
Andersen PM, Sims KB, Xin WW, Kiely R, O'Neill G, Ravits J, Pioro E, Harati Y, Brower RD, Levine JS, Heinicke HU, Seltzer W, Boss M, Brown RH, Jr.. Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes. Amyotroph Lateral Scler Other Motor Neuron Disord 2003;4:62-73.
Filosto M, Mancuso M, Nishigaki Y, Pancrudo J, Harati Y, Gooch C, Mankodi A, Bayne L, Bonilla E, Shanske S, Hirano M, DiMauro S. Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Arch Neurol 2003;60:1279-84.
Horner RD, Kamins KG, Feussner JR, Grambow SC, Hoff-Lindquist J, Harati Y, Mitsumoto H, Pascuzzi R, Spencer PS, Tim R, Howard D, Smith TC, Ryan MA, Coffman CJ, Kasarskis EJ. Occurrence of amyotrophic lateral sclerosis among Gulf War veterans. Neurology 2003;61:742-9.
Bradley WG, Anderson F, Bromberg M, Gutmann L, Harati Y, Ross M, Miller RG. Current management of ALS: comparison of the ALS CARE Database and the AAN Practice Parameter. The American Academy of Neurology. Neurology 2001;57:500-4.
Mendell JR, Barohn RJ, Freimer ML, Kissel JT, King W, Nagaraja HN, Rice R, Campbell WW, Donofrio PD, Jackson CE, Lewis RA, Shy M, Simpson DM, Parry GJ, Rivner MH, Thornton CA, Bromberg MB, Tandan R, Harati Y, Giuliani MJ. Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. Neurology 2001;56:445-9.
Gooch CL, Harati Y. Motor unit number estimation, ALS and clinical trials. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:71-82.
Harati Y, Gooch C, Swenson M, Edelman SV, Greene D, Raskin P, Donofrio P, Cornblath D, Olson WH, Kamin M. Maintenance of the long-term effectiveness of tramadol in treatment of the pain of diabetic neuropathy. J Diabetes Complications 2000;14:65-70.
Nagamitsu S, Matsuura T, Khajavi M, Armstrong R, Gooch C, Harati Y, Ashizawa T. A ""dystrophic"" variant of autosomal recessive myotonia congenita caused by novel mutations in the CLCN1 gene. Neurology 2000;55:1697-703.
Bidichandani SI, Purandare SM, Taylor EE, Gumin G, Machkhas H, Harati Y, Gibbs RA, Ashizawa T, Patel PI. Somatic sequence variation at the Friedreich ataxia locus includes complete contraction of the expanded GAA triplet repeat, significant length variation in serially passaged lymphoblasts and enhanced mutagenesis in the flanking sequence. Hum Mol Genet 1999;8:2425-36.
Harati Y, Gooch C, Swenson M, Edelman S, Greene D, Raskin P, Donofrio P, Cornblath D, Sachdeo R, Siu CO, Kamin M. Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy. Neurology 1998;50:1842-6.
Machkhas H, Bidichandani SI, Patel PI, Harati Y. A mild case of Friedreich ataxia: lymphocyte and sural nerve analysis for GAA repeat length reveals somatic mosaicism. Muscle Nerve 1998;21:390-3.
Machkhas H, Harati Y. Side effects of immunosuppressant therapies used in neurology. Neurol Clin 1998;16:171-88.
Gooch CL, Harati Y. Longitudinal tracking of the same single motor unit in amyotrophic lateral sclerosis. Muscle Nerve 1997;20:511-3.
Shaibani A, Gooch C, Harati Y. Moving toes and myoclonus associated with hereditary neuropathy with liability to pressure palsy (HNPP). Muscle Nerve 1997;20:881-3.
Collard CD, Baker BW, 3rd, Johnson D, Bressler R, Harati Y. Cumulative reduction in serum cholinesterase following repeated therapeutic plasma exchange. J Clin Anesth 1996;8:44-8.
Dunne PW, Ma L, Casey DL, Harati Y, Epstein HF. Localization of myotonic dystrophy protein kinase in skeletal muscle and its alteration with disease. Cell Motil Cytoskeleton 1996;33:52-63.
Harati Y. Diabetes and the nervous system. Endocrinol Metab Clin North Am 1996;25:325-59.
Miller RG, Bouchard JP, Duquette P, Eisen A, Gelinas D, Harati Y, Munsat TL, Powe L, Rothstein J, Salzman P, Sufit RL. Clinical trials of riluzole in patients with ALS. ALS/Riluzole Study Group-II. Neurology 1996;47:S86-90; discussion S90-2.
Siklos L, Engelhardt J, Harati Y, Smith RG, Joo F, Appel SH. Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis. Ann Neurol 1996;39:203-16.
Harati Y, Shaibani AI. Aseptic meningitis and intravenous immunoglobulin therapy. Ann Intern Med 1995;122:316.
Smith RG, Kimura F, Harati Y, McKinley K, Stefani E, Appel SH. Altered muscle calcium channel binding kinetics in autoimmune motoneuron disease. Muscle Nerve 1995;18:620-7.
Di Monte DA, Harati Y, Jankovic J, Sandy MS, Jewell SA, Langston JW. Muscle mitochondrial ATP production in progressive supranuclear palsy. J Neurochem 1994;62:1631-4.
Ashizawa T, Dubel JR, Harati Y. Somatic instability of CTG repeat in myotonic dystrophy. Neurology 1993;43:2674-8.
McKinley KL, Harati Y, Schneider LW. Chronic immune activation in the eosinophilia-myalgia syndrome. Muscle Nerve 1993;16:947-51.
Berti-Mattera LN, Harati Y, Eichberg J. Decreased polyphosphoinositide metabolism accompanies myelinated fiber loss in human peripheral neuropathies. Mol Chem Neuropathol 1992;17:201-8.
Harati Y. Frequently asked questions about diabetic peripheral neuropathies. Neurol Clin 1992;10:783-807.
Rolak LA, Rutecki P, Ashizawa T, Harati Y. Clinical features of Todd's post-epileptic paralysis. J Neurol Neurosurg Psychiatry 1992;55:63-4.
Silver RM, McKinley K, Smith EA, Quearry B, Harati Y, Sternberg EM, Heyes MP. Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. Arthritis Rheum 1992;35:1097-105.
Ballantyne CM, Podet EJ, Patsch WP, Harati Y, Appel V, Gotto AM, Jr., Young JB. Effects of cyclosporine therapy on plasma lipoprotein levels. Jama 1989;262:53-6.
Danon MJ, Carpenter S, Harati Y. Muscle pain associated with tubular aggregates and structures resembling cylindrical spirals. Muscle Nerve 1989;12:265-72.
Appel SH, Stewart SS, Appel V, Harati Y, Mietlowski W, Weiss W, Belendiuk GW. A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis. Arch Neurol 1988;45:381-6.
Niakan E, Harati Y. Sympathetic skin response in diabetic peripheral neuropathy. Muscle Nerve 1988;11:261-4.
Harati Y. Diabetic peripheral neuropathies. Ann Intern Med 1987;107:546-59.
Harati Y, Niakan E, Bloom K, Casar G. Adult onset of nemaline myopathy presenting as diaphragmatic paralysis. J Neurol Neurosurg Psychiatry 1987;50:108-10.
Rosenbaum F, Harati Y, Rolak L, Freedman M. Visual hallucinations in sane people: Charles Bonnet syndrome. J Am Geriatr Soc 1987;35:66-8.
Harati Y, Niakan E. Hydrazine toxicity, pyridoxine therapy, and peripheral neuropathy. Ann Intern Med 1986;104:728-9.
Harati Y, Niakan E. Diabetic thoracoabdominal neuropathy. A cause for chest and abdominal pain. Arch Intern Med 1986;146:1493-4.
Harati Y, Niakan E. Clinical significance of selective nerve fascicular degeneration on sural nerve biopsy specimen. Arch Pathol Lab Med 1986;110:195-7.
Harati Y, Niakan E. The clinical spectrum of inflammatory-angiopathic neuropathy. J Neurol Neurosurg Psychiatry 1986;49:1313-6.
Harati Y, Niakan E, Bergman EW. Childhood dermatomyositis in monozygotic twins. Neurology 1986;36:721-3.
Kalanie H, Niakan E, Harati Y, Rolak LA. Phenytoin-induced benign intracranial hypertension. Neurology 1986;36:443.
Niakan E, Harati Y, Comstock JP. Diabetic autonomic neuropathy. Metabolism 1986;35:224-34.
Niakan E, Harati Y, Rolak LA. Immunosuppressive drug therapy in myasthenia gravis. Arch Neurol 1986;43:155-6.
Niakan E, Harati Y, Rolak LA, Comstock JP, Rokey R. Silent myocardial infarction and diabetic cardiovascular autonomic neuropathy. Arch Intern Med 1986;146:2229-30.
Harati Y, Butler IJ. Congenital hypomyelinating neuropathy. J Neurol Neurosurg Psychiatry 1985;48:1269-76.
Niakan E, Harati Y, Danon MJ. Tubular aggregates: their association with myalgia. J Neurol Neurosurg Psychiatry 1985;48:882-6.
Harati Y, Jackson JA, Benjamin E. Adult onset idiopathic familial brain calcifications. Arch Intern Med 1984;144:2425-7.
Harati Y, Niakan E. Thymectomy for autoimmune disease other than rheumatoid arthritis. Lancet 1984;1:792.
Kundu SK, Harati Y, Misra LK. Sialosylglobotetraosylceramide: a marker for amyotropic lateral sclerosis. Biochem Biophys Res Commun 1984;118:82-9.
Rokey R, Rolak LA, Harati Y, Kutka N, Verani MS. Coronary artery disease in patients with cerebrovascular disease: a prospective study. Ann Neurol 1984;16:50-3.
Ashizawa T, Butler IJ, Harati Y, Roongta SM. A dominantly inherited syndrome with continuous motor neuron discharges. Ann Neurol 1983;13:285-90.
Evans RW, Harati Y. What's new: review of clinical presentations, pathophysiology, and treatment of diabetic neuropathies. Tex Med 1983;79:50-4.
Misra LK, Kasturi SR, Kundu SK, Harati Y, Hazlewood CF, Luthra MG, Yamanashi WS, Munjaal RP, Amtey SR. Evaluation of muscle degeneration in inherited muscular dystrophy by nuclear magnetic resonance techniques. Magn Reson Imaging 1982;1:75-9.
Hoffman TG, Harati Y, Whitaker SH. Transient paraplegia caused by aortic occlusion. Arch Neurol 1981;38:668-9.
Meyer JS, Hayman LA, Amano T, Nakajima S, Shaw T, Lauzon P, Derman S, Karacan I, Harati Y. Mapping local blood flow of human brain by CT scanning during stable xenon inhalation. Stroke 1981;12:426-36.
Frank JP, Harati Y, Butler IJ, Nelson TE, Scott CI. Central core disease and malignant hyperthermia syndrome. Ann Neurol 1980;7:07-Nov.
Harati Y, Matta K. Gomori's trichrome stain. Arch Neurol 1979;36:454-5.
Harati Y, Patten BM. Prednisone use in concurrent autoimmune diseases. Arch Neurol 1979;36:103-6.
Patten BM, Wood JM, Harati Y, Hefferan P, Howell RR. Familial recurrent rhabdomyolysis due to carnitine palmityl transferase deficiency. Am J Med 1979;67:167-71.
Patten BM, Zito G, Harati Y. Histologic findings in motor neuron disease. Relation to clinically determined activity, duration, and severity of disease. Arch Neurol 1979;36:560-4.
Harati Y, Mitchell C. Jakob-Creutzfeldt disease: brief review and precautionary measures. Tex Med 1978;74:52-4.
Patten BM, Harati Y, Acosta L, Jung SS, Felmus MT. Free amino acid levels in amyotrophic lateral sclerosis. Ann Neurol 1978;3:305-9.

Poster Presentations

York MK, Macias A, Schulz PE, Harati Y, Katz J, Woolley-Levine S. Preliminary Validation of the ALS Cognitive Behavioral Screen (ALS-CBS)T. 2nd International Frontotemporal Dementia in ALS Research Conference, London, Ontario Canada (June 10-13, 2007).

Contact Information

Yadollah Harati, M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030

Tel: 713-798-7411
Fax: 713-798-5030
Email: