James D. Frost, Jr., M.D.
Professor of Neurology and Neuroscience
Medical School
Baylor College of Medicine, Houston, TX
Internship
The Methodist Hospital, Houston, TX
Fellowship
Clinical Neurophysiology, Baylor College of Medicine, Houston, TX
Clinical Interests
Clinical neurophysiology. electroencephalography, epilepsy, infantile spasms, sleep disorders
Research Interests
Etiology, pathophysiology and treatment of infantile spasms; development of automated electrophysiological and video techniques for the detection and characterization of epileptic seizures; sleep disorders
Publications
- Mitra J, Glover JR, Ktonas PY, Thitai Kumar A, Mukherjee A, Karayiannis NB, Frost JD, Jr., Hrachovy RA, Mizrahi EM. A multistage system for the automated detection of epileptic seizures in neonatal electroencephalography. J Clin Neurophysiol. 2009;26:218-26.
- Price MG, Yoo JW, Burgess DL, Deng F, Hrachovy RA, Frost JD, Jr., Noebels JL. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with Interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J Neurosci. 2009;29:8752-63.
- Guggenheim MA, Frost JD, Jr., Hrachovy RA. Time interval from a brain insult to the onset of infantile spasms. Pediatr Neurol. 2008;38:34-7.
- Lee CL, Frost JD, Jr., Swann JW, Hrachovy RA. A new animal model of infantile spasms with unprovoked persistent seizures. Epilepsia. 2008;49:298-307.
- Hrachovy RA, Frost JD, Jr. The EEG in selected generalized seizures. J Clin Neurophysiol. 2006;23:312-32.
- Karayiannis NB, Mukherjee A, Glover JR, Ktonas PY, Frost JD, Jr., Hrachovy RA, Mizrahi EM. Detection of pseudosinusoidal epileptic seizure segments in the neonatal EEG by cascading a rule-based algorithm with a neural network. IEEE Trans Biomed Eng. 2006;53:633-41.
- Karayiannis NB, Tao G, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures based on motion segmentation methods. Clin Neurophysiol. 2006;117:1585-94.
- Karayiannis NB, Xiong Y, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures based on motion tracking methods. J Clin Neurophysiol. 2006;23:521-31.
- Karayiannis NB, Xiong Y, Tao G, Frost JD, Jr., Wise MS, Hrachovy RA, Mizrahi EM. Automated detection of videotaped neonatal seizures of epileptic origin. Epilepsia. 2006;47:966-80.
- Frost JD, Jr., Hrachovy RA. Pathogenesis of infantile spasms: a model based on developmental desynchronization. J Clin Neurophysiol. 2005;22:25-36.
- Karayiannis NB, Sami A, Frost JD, Jr., Wise MS, Mizrahi EM. Automated extraction of temporal motor activity signals from video recordings of neonatal seizures based on adaptive block matching. IEEE Trans Biomed Eng. 2005;52:676-86.
- Karayiannis NB, Tao G, Xiong Y, Sami A, Varughese B, Frost JD, Jr., Wise MS, Mizrahi EM. Computerized motion analysis of videotaped neonatal seizures of epileptic origin. Epilepsia. 2005;46:901-17.
- Karayiannis NB, Varughese B, Tao G, Frost JD, Jr., Wise MS, Mizrahi EM. Quantifying motion in video recordings of neonatal seizures by regularized optical flow methods. IEEE Trans Image Process. 2005;14:890-903.
- Karayiannis NB, Xiong Y, Frost JD, Jr., Wise MS, Mizrahi EM. Improving the accuracy and reliability of motion tracking methods used for extracting temporal motor activity signals from video recordings of neonatal seizures. IEEE Trans Biomed Eng. 2005;52:747-9.
- Karayiannis NB, Xiong Y, Frost JD, Jr., Wise MS, Mizrahi EM. Quantifying motion in video recordings of neonatal seizures by robust motion trackers based on block motion models. IEEE Trans Biomed Eng. 2005;52:1065-77.
- Mitra J, Glover J, Ktonas P, Frost J, Hrachovy R, Mizrahi E. Rule-enhanced Clustering in the Detection of Neonatal Seizures. Conf Proc IEEE Eng Med Biol Soc. 2005;1:948-51.
- Karayiannis NB, Mukherjee A, Glover JR, Ktonas PY, Frost JD, Jr., Hrachovy RA, Mizrahi EM. Quantifying and visualizing uncertainty in EEG data of neonatal seizures. Conf Proc IEEE Eng Med Biol Soc. 2004;1:423-6.
- Karayiannis NB, Sami A, Frost JD, Jr., Wise MS, Mizrahi EM. Quantifying motion in video recordings of neonatal seizures by feature trackers based on predictive block matching. Conf Proc IEEE Eng Med Biol Soc. 2004;2:1447-50.
- Karayiannis NB, Tao G, Varughese B, Frost JD, Jr., Wise MS, Mizrahi EM. Discrete optical flow estimation methods and their application in the extraction of motion strength signals from video recordings of neonatal seizures. Conf Proc IEEE Eng Med Biol Soc. 2004;3:1718-21.
- Mitra J, Glover JR, Frost JD, Ktonas PA, Hrachovy RA, Mizrahi EM. Enhanced spatio-temporal clustering in the detection of neonatal seizures using context-based rules. Conf Proc IEEE Eng Med Biol Soc. 2004;7:4717-20.
- Hrachovy RA, Frost JD, Jr. Infantile epileptic encephalopathy with hypsarrhythmia (infantile spasms/West syndrome). J Clin Neurophysiol. 2003;20:408-25.
- Karayiannis NB, Srinivasan S, Bhattacharya R, Wise MS, Frost JD, Jr., Mizrahi EM. Extraction of motion strength and motor activity signals from video recordings of neonatal seizures. IEEE Trans Med Imaging. 2001;20:965-80.
- Ramabhadran B, Frost JD, Jr., Glover JR, Ktonas PY. An automated system for epileptogenic focus localization in the electroencephalogram. J Clin Neurophysiol. 1999;16:59-68.
- Glaze DG, Schultz RJ, Frost JD. Rett syndrome: characterization of seizures versus non-seizures. Electroencephalogr Clin Neurophysiol. 1998;106:79-83.
- Chatrian GE, Bergamasco B, Bricolo A, Frost JD, Jr., Prior PF. IFCN recommended standards for electrophysiologic monitoring in comatose and other unresponsive states. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol. 1996;99:103-22.
- Frost JD, Jr., Hrachovy RA, Glaze DG, Rettig GM. Alpha rhythm slowing during initiation of carbamazepine therapy: implications for future cognitive performance. J Clin Neurophysiol. 1995;12:57-63.
- Lee CL, Hrachovy RA, Smith KL, Frost JD, Jr., Swann JW. Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood. Brain Res. 1995;677:97-109.
- Hrachovy RA, Frost JD, Jr., Glaze DG. Coupling of focal electrical seizure discharges with infantile spasms: incidence during long-term monitoring in newly diagnosed patients. J Clin Neurophysiol. 1994;11:461-4.
- Hrachovy RA, Frost JD, Jr., Glaze DG. High-dose, long-duration versus low-dose, short-duration corticotropin therapy for infantile spasms. J Pediatr. 1994;124:803-6.
- Percy AK, Glaze DG, Schultz RJ, Zoghbi HY, Williamson D, Frost JD, Jr., Jankovic JJ, del Junco D, Skender M, Waring S, et al. Rett syndrome: controlled study of an oral opiate antagonist, naltrexone. Ann Neurol. 1994;35:464-70.
- Butte NF, Jensen CL, Moon JK, Glaze DG, Frost JD, Jr. Sleep organization and energy expenditure of breast-fed and formula-fed infants. Pediatr Res. 1992;32:514-9.
- Frost JD, Jr., Hrachovy RA, Glaze DG. Spike morphology in childhood focal epilepsy: relationship to syndromic classification. Epilepsia. 1992;33:531-6.
- Frost JD, Jr., Hrachovy RA, Glaze DG, McCully MI. Sleep modulation of interictal spike configuration in untreated children with partial seizures. Epilepsia. 1991;32:341-6.
- Hrachovy RA, Frost JD, Jr., Glaze DG, Kellaway P. Surgical treatment for infantile spasms? Ann Neurol. 1991;29:110-2.
- Hrachovy RA, Glaze DG, Frost JD, Jr. A retrospective study of spontaneous remission and long-term outcome in patients with infantile spasms. Epilepsia. 1991;32:212-4.
- Glover JR, Jr., Raghavan N, Ktonas PY, Frost JD, Jr. Context-based automated detection of epileptogenic sharp transients in the EEG: elimination of false positives. IEEE Trans Biomed Eng. 1989;36:519-27.
- Hrachovy RA, Frost JD, Jr. Infantile spasms. Cleve Clin J Med. 1989;56 Suppl Pt 1:S10-6; dicussion S40-2.
- Hrachovy RA, Frost JD, Jr. Infantile spasms. Pediatr Clin North Am. 1989;36:311-29.
- Hrachovy RA, Frost JD, Jr., Glaze DG, Rose D. Treatment of infantile spasms with methysergide and alpha-methylparatyrosine. Epilepsia. 1989;30:607-10.
- Frost JD, Jr., Glaze DG, Rosen CL. Munchausen's syndrome by proxy and video surveillance. Am J Dis Child. 1988;142:917-8.
- Glaze DG, Hrachovy RA, Frost JD, Jr., Kellaway P, Zion TE. Prospective study of outcome of infants with infantile spasms treated during controlled studies of ACTH and prednisone. J Pediatr. 1988;112:389-96.
- Hrachovy RA, Frost JD, Jr., Glaze DG. Treatment of infantile spasms with tetrabenazine. Epilepsia. 1988;29:561-3.
- Hrachovy RA, Frost JD, Jr., Pollack MS, Glaze DG. Serologic HLA typing in infantile spasms. Epilepsia. 1988;29:817-9.
- Veregge S, Frost JD, Jr. Relationship between single-unit activity and the electroencephalogram in a neocortical, cobalt-induced epileptogenic focus. Electroencephalogr Clin Neurophysiol. 1988;69:34-44.
- Frost JD, Jr. Data reduction methods for intensive neurodiagnostic monitoring: future directions for development. Adv Neurol. 1987;46:271-9.
- Glaze DG, Frost JD, Jr., Zoghbi HY, Percy AK. Rett's syndrome. Correlation of electroencephalographic characteristics with clinical staging. Arch Neurol. 1987;44:1053-6.
- Glaze DG, Frost JD, Jr., Zoghbi HY, Percy AK. Rett's syndrome: characterization of respiratory patterns and sleep. Ann Neurol. 1987;21:377-82.
- Hrachovy RA, Frost JD, Jr., Gospe SM, Jr., Glaze DG. Infantile spasms following near-drowning: a report of two cases. Epilepsia. 1987;28:45-8.
- Jerger J, Chmiel R, Glaze D, Frost JD, Jr. Rate and filter dependence of the middle-latency response in infants. Audiology. 1987;26:269-83.
- Frost JD, Jr., Kellaway P, Hrachovy RA, Glaze DG, Mizrahi EM. Changes in epileptic spike configuration associated with attainment of seizure control. Ann Neurol. 1986;20:723-6.
- Glaze DG, Hrachovy RA, Frost JD, Jr., Zion TE, Bryan RN. Computed tomography in infantile spasms: effects of hormonal therapy. Pediatr Neurol. 1986;2:23-7.
- Jerger J, Chmiel R, Frost JD, Jr., Coker N. Effect of sleep on the auditory steady state evoked potential. Ear Hear. 1986;7:240-5.
- McGuire DA, Frost JD, Floerchinger SL. Local anesthesia and arthroscopic surgery of the knee. Alaska Med. 1986;28:20-4.
- Rosen CL, Frost JD, Jr., Glaze DG. Child abuse and recurrent infant apnea. J Pediatr. 1986;109:1065-7.
- Rosen CL, Glaze DG, Frost JD, Jr. Home monitor follow-up of persistent apnea and bradycardia in preterm infants. Am J Dis Child. 1986;140:547-50.
- Frost JD, Jr. Automatic recognition and characterization of epileptiform discharges in the human EEG. J Clin Neurophysiol. 1985;2:231-49.
- Kellaway P, Frost JD, Jr. Monitoring at the Baylor College of Medicine, Houston. Electroencephalogr Clin Neurophysiol Suppl. 1985;37:403-14.
- Veregge S, Frost JD, Jr. A simple inexpensive, hydraulic microdrive for recording neocortical unit activity in the unanesthetized rat. Electroencephalogr Clin Neurophysiol. 1985;61:94-7.
- Hrachovy RA, Frost JD, Jr., Glaze DG. What have we learned about sudden infant death? N Engl J Med. 1984;310:787-8.
- Hrachovy RA, Frost JD, Jr., Kellaway P. Hypsarrhythmia: variations on the theme. Epilepsia. 1984;25:317-25.
- Jankovic J, Glaze DG, Frost JD, Jr. Effect of tetrabenazine on tics and sleep of Gilles de la Tourette's syndrome. Neurology. 1984;34:688-92.
- Rosen CL, Glaze DG, Frost JD, Jr. Hypoxemia associated with feeding in the preterm infant and full-term neonate. Am J Dis Child. 1984;138:623-8.
- Glaze DG, Frost JD, Jr., Jankovic J. Sleep in Gilles de la Tourette's syndrome: disorder of arousal. Neurology. 1983;33:586-92.
- Hrachovy RA, Frost JD, Jr., Kellaway P, Zion TE. Double-blind study of ACTH vs prednisone therapy in infantile spasms. J Pediatr. 1983;103:641-5.
- Mizrahi EM, Maulsby RL, Frost JD, Jr. Improved wave V resolution by dual-channel brain stem auditory evoked potential recording. Electroencephalogr Clin Neurophysiol. 1983;55:105-7.
- Rosen CL, Frost JD, Jr., Bricker T, Tarnow JD, Gillette PC, Dunlavy S. Two siblings with recurrent cardiorespiratory arrest: Munchausen syndrome by proxy or child abuse? Pediatrics. 1983;71:715-20.
- Rosen CL, Frost JD, Jr., Harrison GM. Infant apnea: polygraphic studies and follow-up monitoring. Pediatrics. 1983;71:731-6.
- McGuire DA, Brudenell R, Frost JD, Newman MH. Arthroscopy: a perspective. Alaska Med. 1982;24:46-50.
- Hrachovy RA, Frost JD, Jr., Kellaway P. Sleep characteristics in infantile spasms. Neurology. 1981;31:688-93.
- Jankovic J, Frost JD, Jr. Quantitative assessment of parkinsonian and essential tremor: clinical application of triaxial accelerometry. Neurology. 1981;31:1235-40.
- Saltzberg B, Kellaway P, Burton WD, Jr., Frost JD, Jr. Epilepsy: a heuristic model for relating nocturnal sleep EEG spike distributions to the risk of seizure. Int J Biomed Comput. 1981;12:9-16.
- Frost JD, Jr., Hillman CE, Jr., Kellaway P. Automatic interpretation of EEG: analysis of background activity. Comput Biomed Res. 1980;13:242-57.
- Hrachovy RA, Frost JD, Jr., Kellaway P, Zion T. A controlled study of ACTH therapy in infantile spasms. Epilepsia. 1980;21:631-6.
- Kellaway P, Frost JD, Jr., Crawley JW. Time modulation of spike-and-wave activity in generalized epilepsy. Ann Neurol. 1980;8:491-500.
- Frost JD, Jr. Microprocessor-based EEG spike detection and quantification. Int J Biomed Comput. 1979;10:357-73.
- Frost JD, Jr., DeLucchi MR. Insomnia in the elderly: treatment with flurazepam hydrochloride. J Am Geriatr Soc. 1979;27:541-6.
- Hrachovy RA, Frost JD, Jr., Kellaway P, Zion T. A controlled study of prednisone therapy in infantile spasms. Epilepsia. 1979;20:403-7.
- Kellaway P, Frost JD, Jr., Crawley JW. Time modulation of ictal and interictal spike-and-wave activity in generalized epilepsy. Trans Am Neurol Assoc. 1979;104:92-3.
- Kellaway P, Hrachovy RA, Frost JD, Jr., Zion T. Precise characterization and quantification of infantile spasms. Ann Neurol. 1979;6:214-8.
- Frost JD, Jr. Triaxial vector accelerometry: a method for quantifying tremor and ataxia. IEEE Trans Biomed Eng. 1978;25:17-27.
- Frost JD, Jr., Hrachovy RA, Kellaway P, Zion T. Quantitative analysis and characterization of infantile spasms. Epilepsia. 1978;19:273-82.
- Carrie JR, Frost JD, Jr. Clinical evaluation of a method of quantification of generalized spike-wave EEG patterns by computer during prolonged recordings. Comput Biomed Res. 1977;10:449-57.
- Fann WE, Stafford JR, Malone RL, Frost JD, Jr., Richman BW. Clinical research techniques in tardive dyskinesia. Am J Psychiatry. 1977;134:759-62.
- Frost JD, Jr., Shumate WH, Salamy JG, Booher CR. Sleep monitoring: the second manned Skylab mission. Aviat Space Environ Med. 1976;47:372-82.
- Frost JD, Jr., Shumate WH, Booher CR, DeLucchi MR. The Skylab sleep monitoring experiment: methodology and initial results. Acta Astronaut. 1975;2:319-36.
- Frost JD, Jr., Shumate WH, Salamy JG, Booher CR. Skylab sleep monitoring experiment (M133). . 1974;1:.
- Frost JD, Jr., Carrie JR, Borda RP, Kellaway P. The effects of dalmane (flurazepam hydrochloride) on human EEG characteristics. Electroencephalogr Clin Neurophysiol. 1973;34:171-5.
- Hutton JT, Frost JD, Jr., Foster J. The influence of the cerebellum in cat penicillin epilepsy. Epilepsia. 1972;13:401-8.
- Carrier JR, Frost JD, Jr. A small computer system for EEG wavelength-amplitude profile analysis. Int J Biomed Comput. 1971;2:251-63.
- Frost JD, Jr. An automatic sleep analyzer. Electroencephalogr Clin Neurophysiol. 1970;29:88-92.
- Frost JD. Wave length analysis of the EEG--the alpha profile. Electroencephalogr Clin Neurophysiol. 1969;27:702-3.
- Frost JD, Jr. Statistical analysis of EEG-single neuron relationships. Electroencephalogr Clin Neurophysiol. 1969;27:550-1.
- Borda RP, Frost JD, Jr. Error reduction in small sample averaging through the use of the median rather than the mean. Electroencephalogr Clin Neurophysiol. 1968;25:391-2.
- Frost JD, Jr. EEG-intracellular potential relationships in isolated cerebral cortex. Electroencephalogr Clin Neurophysiol. 1968;24:434-43.
- Frost JD, Jr., Elazar Z. Three-dimensional selective amplitude histograms: a statistical approach to EEG-single neuron relationships. Electroencephalogr Clin Neurophysiol. 1968;25:499-503.
- Low MD, Frost JD, Jr., Maulsby RL, McSherry W. Electroencephalographic correlates of preparation set. Electroencephalogr Clin Neurophysiol. 1968;24:286.
- Frost JD, Jr. Comparison of intracellular potentials and ECoG activity in isolated cerebral cortex. Electroencephalogr Clin Neurophysiol. 1967;23:89-90.
- Frost JD, Jr. An averaging technique for detection of EEG-intracellular potential relationships. Electroencephalogr Clin Neurophysiol. 1967;23:179-81.
- Frost JD, Jr., Low MD. An electronic method for determining time-locked changes in neuronal firing rate. Electroencephalogr Clin Neurophysiol. 1967;23:176-8.
- Proler ML, Frost JD, Jr., Maulsby RL, Crawley JW. Electroencephalography. Prog Neurol Psychiatry. 1967;22:260-94.
- Frost JD, Jr., Gol A. Computer determination of relationships between EEG activity and single unit discharges in isolated cerebral cortex. Exp Neurol. 1966;14:506-19.
- Frost JD, Jr., Kellaway P, Gol A. Single-unit discharges in isolated cerebral cortex. Exp Neurol. 1966;14:305-16.
- Maulsby RL, Frost JD, Jr., Graham MH. A simple electronic method for graphing EEG sleep patterns. Electroencephalogr Clin Neurophysiol. 1966;21:501-3.
- Proler ML, Frost JD, Jr., Maulsby RL, Crawley JW. Electroencephalography. Prog Neurol Psychiatry. 1966;21:330-57.
- Proler ML, Frost JD, Jr., Maulsby RL, Crawley JW. Electroencephalography. Prog Neurol Psychiatry. 1965;20:439-54.
- Winter DL, Frost JD, Jr. Recovery Cycles in the Lemniscal System. Electroencephalogr Clin Neurophysiol. 1964;16:459-69.
Books and Volumes
- Frost JD, Jr., Hrachovy RA. Infantile spasms: diagnosis, management, and prognosis. Boston: Kluwer Academic Publishers; 2003.
Book Chapters
- Hrachovy RA, Frost JD, Jr. Severe encephalopathic epilepsy in infants: infantile spasms (West syndrome). In: Pellock JM, Bourgeois BFD, Dodson WE, editors. Pediatric epilepsy: diagnosis and therapy. 3rd ed. New York: Demos; 2008. p. 249-268.
- Hrachovy RA, Frost JD, Jr. Adrenocorticotropic hormone and steroids. In: Engel J, Jr., Pedley TA, editors. Epilepsy — a comprehensive textbook. 2nd ed. Philadelphia: Wolters Kluwer | Lippincott Williams & Wilkins; 2008. p. 1519-1529.
- Frost JD, Jr. EEG in aviation, space exploration, and diving. In: Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: basic principles, clinical applications and related fields. 5th ed. Baltimore: Williams and Wilkins; 2005. p. 683-688.
- Frost JD, Jr., Wise MS. Sleep disorders. In: Rolak LA, editor. Neurology secrets. 4th ed. Philadelphia: Hanley & Belfus, Inc.; 2005. p. 159-192.
- Frost JD, Jr. Sleep disorders. In: Rolak LA, editor. Neurology secrets. 3rd ed. Philadelphia: Hanley and Belfus; 2001. p. 301-308.
- Hrachovy RA, Frost JD, Jr. Severe encephalopathic epilepsy in infants: West syndrome. In: Pellock JM, Dodson WE, Bourgeois BFD, editors. Pediatric epilepsy: diagnosis and therapy. 2nd ed. New York: Demos; 2001. p. 177-191.
- Frost JD, Jr. EEG in aviation, space exploration, and diving. In: Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: basic principles, clinical applications and related fields. 4th ed. Baltimore: Williams and Wilkins; 1999. p. 656-659.
- Frost JD, Jr. Sleep disorders. In: Rolak LA, editor. Neurology secrets. 2nd ed. Philadelphia: Hanley and Belfus; 1998. p. 287-243.
- Frost JD, Jr. EEG in aviation, space exploration, and diving. In: Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: basic principles, clinical applications and related fields. 3rd ed. Baltimore: William and Wilkins; 1993. p. 615-618.
- Frost JD, Jr. Sleep disorders. In: Rolak LA, editor. Neurology secrets. Philadelphia: Hanley and Belfus; 1993. p. 289-296.
- Hrachovy RA, Frost JD, Jr. Severe encephalopathic epilepsy in infants: infantile spasms. In: Dodson WE, Pellock JM, editors. Pediatric epilepsy: diagnosis and therapy. New York: Demos; 1993. p. 135-145.
- Hrachovy RA, Frost JD, Jr. Infantile spasms. In: Dam M, Gram L, editors. Comprehensive epileptology. New York: Raven Press; 1990. p. 113-121.
- Kellaway P, Frost JD, Jr., Crawley JW. The relationship between sleep spindles and spike-and-wave bursts in human epilepsy. In: Avoli M, Gloor P, Kostopoulos G, Naquet R, editors. Generalized epilepsy: neurobiological approaches. Boston: Birkhauser Boston Inc.; 1990. p. 36-48.
- Hrachovy RA, Frost JD, Jr. Infantile spasms: a disorder of the developing nervous system. In: Kellaway P, Noebels JL, editors. Problems and concepts in developmental neurophysiology. Baltimore: Johns Hopkins University Press; 1989. p. 131-147.
- Hrachovy RA, Frost JD, Jr. Infantile spasms. In: Pellock JM, editor. The pediatric clinics of North America. Philadelphia: WB Saunders; 1989. p. 311-329.
- Frost JD, Jr. Mimetic techniques. In: Gevins AS, Rémond A, editors. Methods of analysis of brain electrical and magnetic signals. EEG handbook. Vol. 1. Amsterdam: Elsevier Science Publishers BV; 1987. p. 195-209.
- Frost JD, Jr. EEG in aviation, space exploration, and diving. In: Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: basic principles, clinical applications and related fields. 2nd ed. Baltimore: Urban and Schwarzenberg; 1987. p. 549-552.
- Frost JD, Jr. Data reduction methods for intensive neurodiagnostic monitoring: future directions for development. In: Gumnit RJ, editor. Advances in neurology. Intensive neurodiagnostic monitoring. Vol. 46. New York: Raven Press; 1986. p. 271-279.
- Hrachovy RA, Frost JD, Jr. Intensive monitoring of infantile spasms. In: Schmidt D, Morselli PL, editors. Intractable epilepsy: experimental and clinical aspects. New York: Raven Press; 1986. p. 87-97.
- Kellaway P, Frost JD, Jr. Monitoring at the Baylor College of Medicine, Houston (EEG Suppl. No. 37). In: Gotman J, Ives JR, Gloor P, editors. Long-term monitoring in epilepsy. Amsterdam: Elsevier Science Publishers BV; 1985. p. 403-414.
- Mathew NT, Glaze DG, Frost JD, Jr. Sleep apnea and other sleep abnormalities in primary headache disorders. In: Rose FC, editor. Migraine: clinical and research advances. Proceedings of the 5th International Migraine Symposium. London: Karger, Basel; 1984. p. 40-49.
- Kellaway P, Frost JD, Jr. Biorhythmic modulation of epileptic events. In: Pedley TA, Meldrum BS, editors. Recent advances in epilepsy. Edinburgh: Churchill Livingstone; 1983. p. 139-154.
- Kellaway P, Frost JD, Jr., Hrachovy RA. Infantile spasms. In: Morselli PL, Pippenger CE, Penry JK, editors. Antiepileptic drug therapy in pediatrics. New York: Raven Press; 1983. p. 115-136.
- Frost JD, Jr. EEG in aviation, space exploration, and diving. In: Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: basic principles, clinical applications and related fields. Baltimore: Urban and Schwarzenberg; 1982. p. 461-464.
- Kellaway P, Frost JD, Jr., Hrachovy RA. Infantile spasms. In: Gellis S, Kagan B, editors. Current pediatric therapy. Vol. 10. Philadelphia: WB Saunders; 1982. p. 71-72.
- Hrachovy RA, Frost JD, Jr., Kellaway P, Zion T. A controlled study of prednisone therapy in infantile spasms. In: Wada JA, Penry JK, editors. Advances in epileptology: the Xth Epilepsy International Symposium. New York: Raven Press; 1980. p. 335-339.
- Frost JD, Jr., Shumate WH, Salamy JG, Booher CR. Experiment M133. Sleep monitoring on Skylab. In: Johnston RS, Dietlein LF, editors. Biomedical results from Skylab. Washington, DC: NASA SP-377. Scientific and Technical Information Office, National Aeronautics and Space Administration; 1977. p. 113-126.
- Frost JD, Jr. Physiological basis of normal EEG rhythms. In: Chatrian GE, Lairy GC, editors. Handbook of electroencephalography and clinical neurophysiology. The EEG of the waking adult. Vol. 6, Part A. Amsterdam: Elsevier Scientific; 1976. p. 150-160.
- Frost JD, Jr., Barlow JS, Harper RM. Graphic and magnetic-tape recording of bioelectrical phenomena. In: Rémond A, editor. Techniques and methods of data acquisition of EEG and EMG, Part B. Vol. 3. Amsterdam: Elsevier Scientific; 1976. p. 3-63.
- Frost JD, Jr., Shumate WH, Booher CR, DeLucchi MR. The Skylab sleep monitoring experiment: methodology and initial results. In: Graybiel A, editor. Proceedings of Fifth International Symposium on Basic Environmental Problems of Man in Space. New York: Pergamon Press; 1976. (Reprinted from Acta Astronautica, 1975, 2: 319-336).
- Maulsby RL, Frost JD, Jr., Blanc CJ. Special environments and selection problems. In: Chatrian GE, Lairy GC, editors. Handbook of electroencephalography and clinical neurophysiology. The EEG of the waking adult. Vol. 6, Part A. Amsterdam: Elsevier Scientific; 1976. p. 257-274.
- Frost JD, Jr., DeLucchi MR. Electrophysiological home-recorded sleep study in insomnia. In: Burch N, Altshuler HL, editors. Behavior and brain electrical activity. New York: Plenum Press; 1975. p. 113-125.
- Frost JD, Jr., Shumate WH, Salamy JG, Booher CR. Sleep characteristics during the 28- and 59-day Skylab missions. In: Burch N, Altshuler HL, editors. Behavior and brain electrical activity. New York: Plenum Press; 1975. p. 31-53.
- Frost JD, Jr., Shumate WH. A disposable electrode system for EEG monitoring during long-term space flight. In: Miller HA, Harrison DC, editors. Biomedical electrode technology—Theory and practice. New York: Academic Press; 1974. p. 377-385.
- Carrie JRG, Frost JD, Jr. Wavelength-amplitude profile analysis in clinical EEG. In: Kellaway P, Petérsen I, editors. Automation of clinical electroencephalography. New York: Raven Press; 1973. p. 65-74.
- Frost JD, Jr. A sleep-analysis system as a model of automation of clinical electroencephalography. In: Kellaway P, Petérsen I, editors. Automation of clinical electroencephalography. New York: Raven Press; 1973. p. 31-43.
- Frost JD, Jr., Salamy JG. Sleep-monitoring—Experiment M133. In: Inc. B, editor. Skylab Medical Experiments Altitude Test (SMEAT). NASA TMX-58115; 1973. p. 12.1-12.21.
- Cooper R, Frost JD, Jr., Walter DO. Digital processing of bioelectrical phenomena. In: Walter DO, editor. Handbook of electroencephalography and clinical neurophysiology. Vol. 4, Part B. Amsterdam: Elsevier Publishing Co.; 1972.
- Low MD, Baker M, Ferguson R, Frost JD, Jr. Acquisition of electroencephalographic data in a large regional hospital: bringing the brain waves to the computer. In: Lew A, editor. Computers in biomedicine. A supplement to the Proceedings of the Fifth International Conference on System Sciences. North Hollywood (CA): Western Periodicals Co.; 1972. p. 9-11.
- Frost JD, Jr., Kellaway P, DeLucchi MR. Automatic EEG acquisition and data analysis system. In: Pauli DC, Cole HA, editors. Project Tektite I ONR Report DR 153. Washington, DC: Office of Naval Research; 1970. p. A54-A69.
Poster Presentations
- Mizrahi EM, Frost JD, Jr., Friedman DE, Hrachovy RA, Slater JD. Assessment of Acute Mild Traumatic Brain Injury by Quantitative EEG Analysis — Mission Connect: Mild Traumatic Brain Injury Translational Research Consortium — The Integrated Clinical Protocol: Neurophysiology Core. US Department of Defense, Military Health Research Forum 2009 in Kansas City, Missouri (Aug. 31 - Sept. 3, 2009).
Contact Information
James D. Frost, Jr., M.D.
Department of Neurology
Baylor College of Medicine
One Baylor Plaza, MS NB302
Houston, Texas 77030
Tel: 713-798-0980
Fax: 713-798-0984
Email: