Gary D. Clark, M.D.

Professor of Pediatrics
Section Chief, Pediatric Neurology and Developmental Neuroscience

Clinical Service Area

Pediatrics

Specialty

Neurology

Board Certification

American Board of Pediatrics
American Board of Pediatrics, Developmental-Behavioral Pediatrics

Clinic Appointments

832-822-5046

Consult

832-822-1750

Medical School

Louisiana State University Medical School, New Orleans, LA

Residency

Pediatrics, Harvard Medical School/Children's Hospital, Boston, MA

Fellowship

Neurology, Washington University School of Medicine, St. Louis, MO
Child Neurology, Washington University School of Medicine, St. Louis, MO

Clinical Interests

Developmental disorders, seizure disorders, learning disorders

Clinic Location

Blue Bird Circle Clinic for Pediatric Neurology
TCH Clinical Care Center
6701 Fannin St., 9th Floor
Houston, TX 77030

Research Interests

Genetic and biochemical mechansisms underlying disorders of neuronal migration and brain development; Lissencephaly associated genes Lis1 (Pafah1b1), Reelin (Reln), and Doublecortin (DCX)

Publications
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Berg JS, Brunetti-Pierri N, Peters SU, Kang SH, Fong CT, Salamone J, Freedenberg D, Hannig VL, Prock LA, Miller DT, Raffalli P, Harris DJ, Erickson RP, Cunniff C, Clark GD, Blazo MA, Peiffer DA, Gunderson KL, Sahoo T, Patel A, et al.. Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region. Genet Med 2007;9:427-41.
Clark GD. The classification of cortical dysplasias through molecular genetics. Brain Dev 2004;26:351-62.
Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nat Genet 2003;35:270-6.
Sutton VR, O'Brien WE, Clark GD, Kim J, Wanders RJ. 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency. J Inherit Metab Dis 2003;26:69-71.
Yan W, Assadi AH, Wynshaw-Boris A, Eichele G, Matzuk MM, Clark GD. Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis. Proc Natl Acad Sci U S A 2003;100:7189-94.
Poolos NP, Das S, Clark GD, Lardizabal D, Noebels JL, Wyllie E, Dobyns WB. Males with epilepsy, complete subcortical band heterotopia, and somatic mosaicism for DCX. Neurology 2002;58:1559-62.
Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY. NudC associates with Lis1 and the dynein motor at the leading pole of neurons. J Neurosci 2001;21:RC187.
Clark GD. Cerebral gyral dysplasias: molecular genetics and cell biology. Curr Opin Neurol 2001;14:157-62.
Bix GJ, Clark GD. Elvax as a slow-release delivery agent for a platelet-activating factor receptor agonist and antagonist. J Neurosci Methods 1997;77:67-74.
Clark GD, Mizuguchi M, Antalffy B, Barnes J, Armstrong D. Predominant localization of the LIS family of gene products to Cajal-Retzius cells and ventricular neuroepithelium in the developing human cortex. J Neuropathol Exp Neurol 1997;56:1044-52.
Clark GD, McNeil RS, Bix GJ, Swann JW. Platelet-activating factor produces neuronal growth cone collapse. Neuroreport 1995;6:2569-75.
Clark GD, McNeil RS, Bix GJ, Swann JW. Lipids as axon guidance molecules?. Neuroreport 1995;6:2446.

Contact Information

Gary D. Clark, M.D.
Department of Pediatrics
Baylor College of Medicine
One Baylor Plaza, MS BCM320
Houston, Texas 77030

Tel: 832-822-1750
Fax: 832-825-1717
Email: