Gary D. Clark, M.D.
Assistant Professor of Pediatrics
Medical Director of Clinic for Attention Problems, TCH
Clinical Service Area
Pediatrics
Specialty
Neurology
Board Certification
Am Bd Pediatrics; Am Bd Psych & Neuro: Neuro with Special Qualification in Child Neurology
Clinic Appointments
832-822-5046
Consult
832-822-1750
Medical School
Louisiana State University Medical School, New Orleans, LA
Residency
Pediatrics, Harvard Medical School/Children's Hospital, Boston, MA
Fellowship
Neurology, Washington University School of Medicine, St. Louis, MO
Child Neurology, Washington University School of Medicine, St. Louis, MO
Clinical Interests
Developmental disorders, seizure disorders, learning disorders
Clinic Location
- Pediatric Neurology Clinic
Clinical Care Center
6701 Fannin, 9th Fl, MC CC 950.04
Houston, TX 77030
Research Interests
Genetic and biochemical mechansisms underlying disorders of neuronal migration and brain development; Lissencephaly associated genes Lis1 (Pafah1b1), Reelin (Reln), and Doublecortin (DCX)
Publications
- Berg JS, Brunetti-Pierri N, Peters SU, Kang SH, Fong CT, Salamone J, Freedenberg D, Hannig VL, Prock LA, Miller DT, Raffalli P, Harris DJ, Erickson RP, Cunniff C, Clark GD, Blazo MA, Peiffer DA, Gunderson KL, Sahoo T, Patel A, et al.. Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region. Genet Med 2007;9:427-41.
- Clark GD. The classification of cortical dysplasias through molecular genetics. Brain Dev 2004;26:351-62.
- Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nat Genet 2003;35:270-6.
- Sutton VR, O'Brien WE, Clark GD, Kim J, Wanders RJ. 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency. J Inherit Metab Dis 2003;26:69-71.
- Yan W, Assadi AH, Wynshaw-Boris A, Eichele G, Matzuk MM, Clark GD. Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis. Proc Natl Acad Sci U S A 2003;100:7189-94.
- Poolos NP, Das S, Clark GD, Lardizabal D, Noebels JL, Wyllie E, Dobyns WB. Males with epilepsy, complete subcortical band heterotopia, and somatic mosaicism for DCX. Neurology 2002;58:1559-62.
- Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY. NudC associates with Lis1 and the dynein motor at the leading pole of neurons. J Neurosci 2001;21:RC187.
- Clark GD. Cerebral gyral dysplasias: molecular genetics and cell biology. Curr Opin Neurol 2001;14:157-62.
- Bix GJ, Clark GD. Elvax as a slow-release delivery agent for a platelet-activating factor receptor agonist and antagonist. J Neurosci Methods 1997;77:67-74.
- Clark GD, Mizuguchi M, Antalffy B, Barnes J, Armstrong D. Predominant localization of the LIS family of gene products to Cajal-Retzius cells and ventricular neuroepithelium in the developing human cortex. J Neuropathol Exp Neurol 1997;56:1044-52.
- Clark GD, McNeil RS, Bix GJ, Swann JW. Platelet-activating factor produces neuronal growth cone collapse. Neuroreport 1995;6:2569-75.
- Clark GD, McNeil RS, Bix GJ, Swann JW. Lipids as axon guidance molecules?. Neuroreport 1995;6:2446.
Contact Information
Gary D. Clark, M.D.
Department of Pediatrics
Baylor College of Medicine
One Baylor Plaza, MS BCM320
Houston, Texas 77030
Tel: 832-822-1750
Fax: 832-825-1717
Email: