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Patrick Spicer

Bioengineering (Rice University)

Undergraduate Institution: Rice University

Year: Fourth-Year Graduate Student

Mentor: Antonios G. Mikos, Ph.D.

Thesis Title: Bone Tissue Engineering for Traumatic Defects

Publications:

Spicer PP, Kretlow JD, Henslee AM, Shi M, Young S, Demian N, Jansen JA, Wong ME, Mikos AG, Kasper FK. In situ formation of porous space maintainers in a composite tissue defect. Journal of biomedical materials research Part A. 2012.
Henslee AM, Spicer PP, Yoon DM, Nair MB, Meretoja VV, Witherel KE, Jansen JA, Mikos AG, Kasper FK. Biodegradable composite scaffolds incorporating an intramedullary rod and delivering bone morphogenetic protein-2 for stabilization and bone regeneration in segmental long bone defects. Acta biomaterialia. 2011;7(10):3627-37.
Mountziaris PM, Spicer PP, Kasper FK, Mikos AG. Harnessing and modulating inflammation in strategies for bone regeneration. Tissue engineering Part B, Reviews. 2011;17(6):393-402.
Shi M, Kretlow JD, Spicer PP, Tabata Y, Demian N, Wong ME, Kasper FK, Mikos AG. Antibiotic-releasing porous polymethylmethacrylate/gelatin/antibiotic constructs for craniofacial tissue engineering. Journal of controlled release: official journal of the Controlled Release Society. 2011;152(1):196-205.
Chew SA, Kretlow JD, Spicer PP, Edwards AW, Baggett LS, Tabata Y, Kasper FK, Mikos AG. Delivery of plasmid DNA encoding bone morphogenetic protein-2 with a biodegradable branched polycationic polymer in a critical-size rat cranial defect model. Tissue engineering Part A. 2011;17(5-6):751-63.
Kretlow JD, Spicer PP, Jansen JA, Vacanti CA, Kasper FK, Mikos AG. Uncultured marrow mononuclear cells delivered within fibrin glue hydrogels to porous scaffolds enhance bone regeneration within critical-sized rat cranial defects. Tissue engineering Part A. 2010;16(12):3555-68.
Spicer PP, Mikos AG. Fibrin glue as a drug delivery system. Journal of controlled release: official journal of the Controlled Release Society. 2010;148(1):49-55.
Kretlow JD, Shi M, Young S, Spicer PP, Demian N, Jansen JA, Wong ME, Kasper FK, Mikos AG. Evaluation of soft tissue coverage over porous polymethylmethacrylate space maintainers within nonhealing alveolar bone defects. Tissue engineering Part C, Methods. 2010;16(6):1427-38.
Shi X, Sitharaman B, Pham QP, Spicer PP, Hudson JL, Wilson LJ, Tour JM, Raphael RM, Mikos AG. In vitro cytotoxicity of single-walled carbon nanotube/biodegradable polymer nanocomposites. J Biomed Mater Res A. 2008. 86(3):813-23.