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James Orengo, Ph.D.

Molecular and Cellular Biology

Undergraduate Institution: Texas A& M University

Year: Advanced Medical Student

Mentor: Tom Cooper, M.D.

Thesis Title : Investigating the pathogenic mechanisms leading to skeletal muscle wasting in Myotonic Dystrophy.

Publications:

Orengo JP, Chambon P, Metzger D, Mosier DR, Snipes GJ, Cooper TA. Expanded CTG repeats within the DMBP 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci USA. 2008; 105(7):2646-51.

Orengo JP, Cooper TA. Alternative splicing in disease. Adv Exp Med Biol. 2007; 623:212-23. Review.

Orengo JP, Bundman D, Cooper TA. A bichormatic fluorescent reporter for cell-based screens of alternative splicing. Nucleic Acids Res. 2006; 34(22):e148.