Rice Herrmann Laboratory
Regulation of HIV Gene Expression
Welcome to the Rice-Herrmann Laboratory homepage. Our laboratory studies how gene expression in regulated in HIV - the virus that causes AIDS. The major focus of our research is on the HIV Tat protein, which is essential for HIV transcription, and on two cellular factors, cyclin T1 and Cdk9, which are necessary for Tat function. We are investigating how cyclin T1 and Cdk9 are regulated in the two cell types that HIV infects - CD4+ T cells and macrophages.
On this website, you will find short summaries of several research projects that are ongoing in the laboratory, information about members of the lab, and some of our laboratory protocols.
The cyclin T1 subunit of the HIV Tat cofactor TAK/P-TEFb is transiently induced during macrophage differentiation.
(Images by C. Herrmann)