Viral Pathogenesis

This course covers the molecular aspects of pathogenesis of eukaryotic virus infections, with emphasis on animal viruses. The first portion of the course features an in-depth discussion of the general mechanisms involved at the various stages of pathogenesis. The second portion of the course is given over to a comprehensive review of selected viruses which were chosen to illustrate different mechanisms of pathogenesis in various organ systems. (Even years, Term 4)

Meeting	Topics	Lecturer
General Concepts
1	Host Range and Tissue Tropism	Conner
2	Discussion / Student presentation - lecture 1	Conner
3	Mechanisms of Disease Production	Conner
4	Discussion / Student presentation - lecture 3	Conner
5	Host Response to Viral Infection:	Blutt
6	Discussion / Student presentation - lecture 5	Blutt
7	Viral Persistence and Latency	Mitchell
8	Viral Persistence and Latency	Mitchell
9	Discussion / Student presentation - lectures 7 & 8	Mitchell
10	Viral Modulation of the Immune Response	Wyde
11	Discussion / Student presentation - lecture 10	Wyde
12	Control and Treatment of Viral Diseases Midterm Exam (Take home) Handed Out	Conner
13	Discussion / Student presentation - lecture 12	Conner
Viral Pathogenesis in Specific Examples
14	Enteric Virus Infections	Conner
15	Respiratory virus infections (Influenza, RSV) Midterm Exam Collected at Start of Class Period	Wyde
16	Virus infections of the CNS (Sindbis)	Mitchell
17	Discussion - lectures 14 - 16	Conner Wyde Mitchell
18	Systemic virus infections (Pox Viruses)	Javier
19	Hematopoetic virus infections (HIV, HTLV)	Sutton
20	Chronic virus hepatitis (Hepatitis B Virus, Hepatitis C Virus)	Slagle
21 & 22	Outside speaker - Combined 2 hour lecture and discussion Arbovirus infections and vector biology (VEE) Discussion / Student presentation - lecture 22	Weaver
23	Discussion / Student presentation - lectures - 18 to 20	Javier Sutton Slagle
24	Final Exam	--