Introduction to Molecular Carcinogenesis
Fundamental concepts and experiments in tumor biology, cancer virology and oncogenes, and growth control are explored in this course. The material presented provides a broad-based introduction to modern cancer research. (Every Year, Term 4).
Lecture |
Topic |
Lecturer |
1 |
Introduction / Pathogenesis / Epidemiology | Medina |
2 |
Growth Factors I: Stimulatory (EGF / TGFa / IGF) | Yeoman |
3 |
Growth Factors II: Inhibitory (TGFb) | Yeoman |
4 |
Cell Cycle and Cancer | Harper |
5 |
Retroviruses | Donehower |
6 |
Oncogenes I: Tyrosine kinases; receptors | Donehower |
7 |
Oncogenes II: Nuclear factors | Donehower |
8 |
Oncogenes III: Cancer and signalling | Donehower |
9 |
Tumor Suppressor Genes I | Slagle |
10 |
Tumor Suppressor Genes II | Slagle |
11 |
Hepadnaviruses | Slagle |
12 |
Papovaviruses / Adenoviruses | Butel |
13 |
Chemical Carcinogenesis | Medina |
14 |
Tumor Progression and Metastasis | Medina |
15 |
Reversion and Inhibition of Carcinogenesis | Medina |
16 |
DNA Repair in Cancer | Donehower |
17 |
Final Exam | -- |